Gene Review:
OCH1 - Och1p
Saccharomyces cerevisiae S288c
Synonyms:
Initiation-specific alpha-1,6-mannosyltransferase, LDB12, NGD29, Outer chain elongation protein 1, YGL038C
- Localization of a yeast early Golgi mannosyltransferase, Och1p, involves retrograde transport. Harris, S.L., Waters, M.G. J. Cell Biol. (1996)
- Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. Gaynor, E.C., te Heesen, S., Graham, T.R., Aebi, M., Emr, S.D. J. Cell Biol. (1994)
- OCH1 encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagine-linked oligosaccharides. Nakayama, K., Nagasu, T., Shimma, Y., Kuromitsu, J., Jigami, Y. EMBO J. (1992)
- Functional characterization of the Hansenula polymorpha HOC1, OCH1, and OCR1 genes as members of the yeast OCH1 mannosyltransferase family involved in protein glycosylation. Kim, M.W., Kim, E.J., Kim, J.Y., Park, J.S., Oh, D.B., Shimma, Y., Chiba, Y., Jigami, Y., Rhee, S.K., Kang, H.A. J. Biol. Chem. (2006)
- The eukaryotic two-component histidine kinase Sln1p regulates OCH1 via the transcription factor, Skn7p. Li, S., Dean, S., Li, Z., Horecka, J., Deschenes, R.J., Fassler, J.S. Mol. Biol. Cell (2002)
- Glycoprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation. Lehle, L., Eiden, A., Lehnert, K., Haselbeck, A., Kopetzki, E. FEBS Lett. (1995)
- Mutation of TRS130, which encodes a component of the TRAPP II complex, activates transcription of OCH1 in Saccharomyces cerevisiae. Yamamoto, K., Jigami, Y. Curr. Genet. (2002)
- Retrograde transport of the mannosyltransferase Och1p to the early Golgi requires a component of the COG transport complex. Bruinsma, P., Spelbrink, R.G., Nothwehr, S.F. J. Biol. Chem. (2004)
- Cdc4 is involved in the transcriptional control of OCH1, a gene encoding alpha-1,6-mannosyltransferase in Saccharomyces cerevisiae. Cui, Z., Horecka, J., Jigami, Y. Yeast (2002)
- Substrate specificity of alpha-1,6-mannosyltransferase that initiates N-linked mannose outer chain elongation in Saccharomyces cerevisiae. Nakayama, K., Nakanishi-Shindo, Y., Tanaka, A., Haga-Toda, Y., Jigami, Y. FEBS Lett. (1997)
- Functional analysis of the ALG3 gene encoding the Dol-P-Man: Man5GlcNAc2-PP-Dol mannosyltransferase enzyme of P. pastoris. Davidson, R.C., Nett, J.H., Renfer, E., Li, H., Stadheim, T.A., Miller, B.J., Miele, R.G., Hamilton, S.R., Choi, B.K., Mitchell, T.I., Wildt, S. Glycobiology (2004)
- SUR1 (CSG1/BCL21), a gene necessary for growth of Saccharomyces cerevisiae in the presence of high Ca2+ concentrations at 37 degrees C, is required for mannosylation of inositolphosphorylceramide. Beeler, T.J., Fu, D., Rivera, J., Monaghan, E., Gable, K., Dunn, T.M. Mol. Gen. Genet. (1997)
- Saccharomyces cerevisiae HOC1, a suppressor of pkc1, encodes a putative glycosyltransferase. Neiman, A.M., Mhaiskar, V., Manus, V., Galibert, F., Dean, N. Genetics (1997)
- Membrane protein retrieval from the Golgi apparatus to the endoplasmic reticulum (ER): characterization of the RER1 gene product as a component involved in ER localization of Sec12p. Sato, K., Nishikawa, S., Nakano, A. Mol. Biol. Cell (1995)