Gene Review:
PRK1 - Prk1p
Saccharomyces cerevisiae S288c
Synonyms:
Actin-regulating kinase PRK1, PAK1, YIL095W, p53-regulating kinase 1
- Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis. Sekiya-Kawasaki, M., Groen, A.C., Cope, M.J., Kaksonen, M., Watson, H.A., Zhang, C., Shokat, K.M., Wendland, B., McDonald, K.L., McCaffery, J.M., Drubin, D.G. J. Cell Biol. (2003)
- Regulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p. Zeng, G., Cai, M. J. Cell Biol. (1999)
- Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast. Cope, M.J., Yang, S., Shang, C., Drubin, D.G. J. Cell Biol. (1999)
- The actin-regulating kinase Prk1p negatively regulates Scd5p, a suppressor of clathrin deficiency, in actin organization and endocytosis. Henry, K.R., D'Hondt, K., Chang, J.S., Nix, D.A., Cope, M.J., Chan, C.S., Drubin, D.G., Lemmon, S.K. Curr. Biol. (2003)
- Identification of novel recognition motifs and regulatory targets for the yeast actin-regulating kinase Prk1p. Huang, B., Zeng, G., Ng, A.Y., Cai, M. Mol. Biol. Cell (2003)
- Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes. Polverino, A., Frost, J., Yang, P., Hutchison, M., Neiman, A.M., Cobb, M.H., Marcus, S. J. Biol. Chem. (1995)
- Dictyostelium PAKc is required for proper chemotaxis. Lee, S., Rivero, F., Park, K.C., Huang, E., Funamoto, S., Firtel, R.A. Mol. Biol. Cell (2004)
- Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth. Andrews, P.D., Stark, M.J. J. Cell. Sci. (2000)
- Prk1p. Zeng, G., Cai, M. Int. J. Biochem. Cell Biol. (2005)
- p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I. Brzeska, H., Knaus, U.G., Wang, Z.Y., Bokoch, G.M., Korn, E.D. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Negative Regulation of Yeast Eps15-like Arp2/3 Complex Activator, Pan1p, by the Hip1R-related Protein, Sla2p, during Endocytosis. Toshima, J., Toshima, J.Y., Duncan, M.C., Cope, M.J., Sun, Y., Martin, A.C., Anderson, S., Yates, J.R., Mizuno, K., Drubin, D.G. Mol. Biol. Cell (2007)
- Interaction with the SH3 domain protein Bem1 regulates signaling by the Saccharomyces cerevisiae p21-activated kinase Ste20. Winters, M.J., Pryciak, P.M. Mol. Cell. Biol. (2005)
- Actin cytoskeleton organization regulated by the PAK family of protein kinases. Eby, J.J., Holly, S.P., van Drogen, F., Grishin, A.V., Peter, M., Drubin, D.G., Blumer, K.J. Curr. Biol. (1998)
- Regulation of yeast actin cytoskeleton-regulatory complex Pan1p/Sla1p/End3p by serine/threonine kinase Prk1p. Zeng, G., Yu, X., Cai, M. Mol. Biol. Cell (2001)
- Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. Moskow, J.J., Gladfelter, A.S., Lamson, R.E., Pryciak, P.M., Lew, D.J. Mol. Cell. Biol. (2000)
- Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity. Lamson, R.E., Takahashi, S., Winters, M.J., Pryciak, P.M. Curr. Biol. (2006)