Gene Review:
MAC1 - Mac1p
Saccharomyces cerevisiae S288c
Synonyms:
CUA1, Metal-binding activator 1, YM9711.11C, YMR021C
- Mapping of the DNA binding domain of the copper-responsive transcription factor Mac1 from Saccharomyces cerevisiae. Jensen, L.T., Posewitz, M.C., Srinivasan, C., Winge, D.R. J. Biol. Chem. (1998)
- MAC1, a nuclear regulatory protein related to Cu-dependent transcription factors is involved in Cu/Fe utilization and stress resistance in yeast. Jungmann, J., Reins, H.A., Lee, J., Romeo, A., Hassett, R., Kosman, D., Jentsch, S. EMBO J. (1993)
- Metalloregulation of FRE1 and FRE2 homologs in Saccharomyces cerevisiae. Martins, L.J., Jensen, L.T., Simon, J.R., Keller, G.L., Winge, D.R., Simons, J.R. J. Biol. Chem. (1998)
- GRISEA, a copper-modulated transcription factor from Podospora anserina involved in senescence and morphogenesis, is an ortholog of MAC1 in Saccharomyces cerevisiae. Borghouts, C., Osiewacz, H.D. Mol. Gen. Genet. (1998)
- Structure-function analysis of the protein-binding domains of Mac1p, a copper-dependent transcriptional activator of copper uptake in Saccharomyces cerevisiae. Serpe, M., Joshi, A., Kosman, D.J. J. Biol. Chem. (1999)
- Immunotherapy of cancer: experimental approach with activated macrophages proliferating in culture. Bartholeyns, J., Lombard, Y., Dumont, S., Hartmann, D., Chokry, M., Giaimis, J., Kaufmann, S., Poindron, P. Cancer Detect. Prev. (1988)
- Copper-mediated repression of the activation domain in the yeast Mac1p transcription factor. Graden, J.A., Winge, D.R. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Identification of the copper chaperone, CUC-1, in Caenorhabditis elegans: tissue specific co-expression with the copper transporting ATPase, CUA-1. Wakabayashi, T., Nakamura, N., Sambongi, Y., Wada, Y., Oka, T., Futai, M. FEBS Lett. (1998)
- Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1. Yamaguchi-Iwai, Y., Serpe, M., Haile, D., Yang, W., Kosman, D.J., Klausner, R.D., Dancis, A. J. Biol. Chem. (1997)
- Functional independence of the two cysteine-rich activation domains in the yeast Mac1 transcription factor. Keller, G., Gross, C., Kelleher, M., Winge, D.R. J. Biol. Chem. (2000)
- Identification of proteins that interact with two regulators of appressorium development, adenylate cyclase and cAMP-dependent protein kinase A, in the rice blast fungus Magnaporthe grisea. Kulkarni, R.D., Dean, R.A. Mol. Genet. Genomics (2004)
- The yeast transcription factor Mac1 binds to DNA in a modular fashion. Jamison McDaniels, C.P., Jensen, L.T., Srinivasan, C., Winge, D.R., Tullius, T.D. J. Biol. Chem. (1999)
- The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator. Georgatsou, E., Mavrogiannis, L.A., Fragiadakis, G.S., Alexandraki, D. J. Biol. Chem. (1997)
- Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae. Peña, M.M., Koch, K.A., Thiele, D.J. Mol. Cell. Biol. (1998)
- Genetic analysis of iron uptake in the yeast Saccharomyces cerevisiae. Dancis, A. J. Pediatr. (1998)
- Mechanisms of copper loading on the Schizosaccharomyces pombe copper amine oxidase 1 expressed in Saccharomyces cerevisiae. Laliberté, J., Labbé, S. Microbiology (Reading, Engl.) (2006)
- Evidence for (Mac1p)2.DNA ternary complex formation in Mac1p-dependent transactivation at the CTR1 promoter. Joshi, A., Serpe, M., Kosman, D.J. J. Biol. Chem. (1999)
- Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays. Gross, C., Kelleher, M., Iyer, V.R., Brown, P.O., Winge, D.R. J. Biol. Chem. (2000)
- Independent metalloregulation of Ace1 and Mac1 in Saccharomyces cerevisiae. Keller, G., Bird, A., Winge, D.R. Eukaryotic Cell (2005)