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MeSH Review:

Intraoperative Period

Schwender, D. et al., Casati, A. et al., Ratge, D. et al., Casati, V. et al., Zárate, E. et al., et al.

Kerssens, Klein, van der Woerd, Bonke, Casati, Bellotti, Gerli, Franco, Oppizzi, Cossolini, Calori, Benussi, Alfieri, Torri, Casati, Albertin, Fanelli, Deni, Berti, Danelli, Grifoni, Torri,

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Disease relevance of Intraoperative Period

Esmolol has also been shown to be effective and safe in attenuating the tachycardia and hypertension seen during the intraoperative period [1].
During intraoperative periods of stress, such as cardiopulmonary bypass and hypothermia, norepinephrine and epinephrine levels were 2-3 times higher in the neurolept patients, compared with the enflurane patients [2].

High impact information on Intraoperative Period

This study evaluated the effects of the treatment using tranexamic acid during the intraoperative period only and compared the results with the effects of the treatment continued into the postoperative period [3].
CONCLUSIONS: Adjunctive use of a variable-rate infusion of adenosine during desflurane-nitrous oxide anesthesia was associated with acceptable hemodynamic stability during the intraoperative period [4].
Supplementary analgesia during the intraoperative period was required by 45% of patients in the lidocaine group as compared with 9% in the mepivacaine group (P=0.02) [5].
No patient consciously recalled the intraoperative period, nor were presented words recognized reliably (Group E, 0.9 +/- 0.8 hits; Group C, 0.8 +/- 0.8 hits) (P = 0.7) [6].
We demonstrated that remifentanil is as effective as sufentanil during the intraoperative period, but that it provides shorter time to extubation and fewer effects on postoperative SpO(2) in the first 7 h after surgery [7].

Biological context of Intraoperative Period

Mean heart rate at induction and in the peroperative period was significantly higher in the group receiving atropine (P < or = 0.001) [8].

Associations of Intraoperative Period with chemical compounds

The aggregation ratios in the sevoflurane and propofol groups were significantly reduced at intraoperative periods compared with preoperative values [9].
These data indicate that MnSSER may be reliably monitored in the intraoperative period during steady-state isoflurane-nitrous oxide anaesthesia [10].
No other factors could be identified, including blood pH, serum creatinine, and drugs given during the peroperative period [11].
Antibiotics, including cefazolin and gentamicin, were administered only in the immediate preoperative and intraoperative periods [12].
This double-blind study found that the calcium-channel blocker, nicardipine, 1 mg intravenously 2 min before tracheal intubation maintained hemodynamic stability during the intraoperative period [13].

Gene context of Intraoperative Period

Before and during movements observed in the intraoperative period or during emergence from general anaesthesia, SEF increased from 12 to 18 Hz, the power in beta band increased and theta power decreased compared with the state of adequate anaesthesia [14].

Analytical, diagnostic and therapeutic context of Intraoperative Period

Donor-specific transfusion and cyclosporine prolong allograft survival when given in the peroperative period [15].

References

Esmolol: a titratable short-acting intravenous beta blocker for acute critical care settings. Turlapaty, P., Laddu, A., Murthy, V.S., Singh, B., Lee, R. Am. Heart J. (1987) [Pubmed]
Magnitude and kinetics of alterations in plasma catecholamines and leukocyte beta-adrenergic receptors in response to anaesthesia and surgery. Ratge, D., Wiedemann, A., Kohse, K.P., Klar, H., Hellberg, K., Wisser, H. J. Clin. Chem. Clin. Biochem. (1990) [Pubmed]
Tranexamic acid administration after cardiac surgery: a prospective, randomized, double-blind, placebo-controlled study. Casati, V., Bellotti, F., Gerli, C., Franco, A., Oppizzi, M., Cossolini, M., Calori, G., Benussi, S., Alfieri, O., Torri, G. Anesthesiology (2001) [Pubmed]
Comparison of adenosine and remifentanil infusions as adjuvants to desflurane anesthesia. Zárate, E., Sá Rêgo, M.M., White, P.F., Duffy, L., Shearer, V.E., Griffin, J.D., Whitten, C.W. Anesthesiology (1999) [Pubmed]
Comparison of mepivacaine and lidocaine for intravenous regional anaesthesia: pharmacokinetic study and clinical correlation. Prieto-Alvarez, P., Calas-Guerra, A., Fuentes-Bellido, J., Martínez-Verdera, E., Benet-Català, A., Lorenzo-Foz, J.P. British journal of anaesthesia. (2002) [Pubmed]
Auditory information processing during adequate propofol anesthesia monitored by electroencephalogram bispectral index. Kerssens, C., Klein, J., van der Woerd, A., Bonke, B. Anesth. Analg. (2001) [Pubmed]
A comparison of remifentanil and sufentanil as adjuvants during sevoflurane anesthesia with epidural analgesia for upper abdominal surgery: effects on postoperative recovery and respiratory function. Casati, A., Albertin, A., Fanelli, G., Deni, F., Berti, M., Danelli, G., Grifoni, F., Torri, G. Anesth. Analg. (2000) [Pubmed]
Comparison of the incidence of complications at induction and emergence in infants receiving oral atropine vs no premedication. Shaw, C.A., Kelleher, A.A., Gill, C.P., Murdoch, L.J., Stables, R.H., Black, A.E. British journal of anaesthesia. (2000) [Pubmed]
The in vitro effects of isoflurane, sevoflurane, and propofol on platelet aggregation. Doğan, I.V., Ovali, E., Eti, Z., Yayci, A., Göğüş, F.Y. Anesth. Analg. (1999) [Pubmed]
Surgical stimulation increases median nerve somatosensory evoked responses during isoflurane-nitrous oxide anaesthesia. Rundshagen, I., Kochs, E., Schulte am Esch, J. British journal of anaesthesia. (1995) [Pubmed]
Effect of body build on the clearance of atracurium: implication for drug dosing. Beemer, G.H., Bjorksten, A.R., Crankshaw, D.P. Anesth. Analg. (1993) [Pubmed]
Perioperative antibiotic prophylaxis for prevention of postoperative neurosurgical infections. A randomized clinical trial. Young, R.F., Lawner, P.M. J. Neurosurg. (1987) [Pubmed]
Optimal dose of nicardipine for maintenance of hemodynamic stability after tracheal intubation and skin incision. Song, D., Singh, H., White, P.F., Gadhiali, M., Griffin, J.D., Klein, K.W. Anesth. Analg. (1997) [Pubmed]
Spectral edge frequency of the electroencephalogram to monitor "depth" of anaesthesia with isoflurane or propofol. Schwender, D., Daunderer, M., Mulzer, S., Klasing, S., Finsterer, U., Peter, K. British journal of anaesthesia. (1996) [Pubmed]
Donor-specific transfusion and cyclosporine prolong allograft survival when given in the peroperative period. Cofer, B.R., Tchervenkov, J.I., Alexander, J.W., Barnwell, S.C. Transplant. Proc. (1991) [Pubmed]

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