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Chemical Compound Review

Suprane     2-(difluoromethoxy)-1,1,1,2- tetrafluoro...

Synonyms: DESFLURANE, Desflurano, Desfluranum, Suprane (TN), AGN-PC-00HTYQ, ...
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  1. Anesthetic effects on the glycerol model of rhabdomyolysis-induced acute renal failure in rats. Lochhead, K.M., Kharasch, E.D., Zager, R.A. J. Am. Soc. Nephrol. (1998) [Pubmed]
  2. Treatment of refractory status epilepticus with inhalational anesthetic agents isoflurane and desflurane. Mirsattari, S.M., Sharpe, M.D., Young, G.B. Arch. Neurol. (2004) [Pubmed]
  3. Delayed onset of malignant hyperthermia induced by isoflurane and desflurane compared with halothane in susceptible swine. Wedel, D.J., Gammel, S.A., Milde, J.H., Iaizzo, P.A. Anesthesiology (1993) [Pubmed]
  4. The cerebral and systemic hemodynamic and metabolic effects of desflurane-induced hypotension in dogs. Milde, L.N., Milde, J.H. Anesthesiology (1991) [Pubmed]
  5. Sympathetic hyperactivity during desflurane anesthesia in healthy volunteers. A comparison with isoflurane. Ebert, T.J., Muzi, M. Anesthesiology (1993) [Pubmed]
  6. The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions. Zhang, B., Dong, Y., Zhang, G., Moir, R.D., Xia, W., Yue, Y., Tian, M., Culley, D.J., Crosby, G., Tanzi, R.E., Xie, Z. J. Biol. Chem. (2008) [Pubmed]
  7. The magnitude and time course of vecuronium potentiation by desflurane versus isoflurane. Wright, P.M., Hart, P., Lau, M., Brown, R., Sharma, M.L., Gruenke, L., Fisher, D.M. Anesthesiology (1995) [Pubmed]
  8. The midlatency auditory evoked potentials predict responsiveness to verbal commands in patients emerging from anesthesia with xenon, isoflurane, and sevoflurane but not with nitrous oxide. Goto, T., Nakata, Y., Saito, H., Ishiguro, Y., Niimi, Y., Morita, S. Anesthesiology (2001) [Pubmed]
  9. Psychomotor performance after desflurane anesthesia: a comparison with isoflurane. Fletcher, J.E., Sebel, P.S., Murphy, M.R., Smith, C.A., Mick, S.A., Flister, M.P. Anesth. Analg. (1991) [Pubmed]
  10. Desflurane analgesia for vaginal delivery. Abboud, T.K., Swart, F., Zhu, J., Donovan, M.M., Peres Da Silva, E., Yakal, K. Acta anaesthesiologica Scandinavica. (1995) [Pubmed]
  11. Midlatency auditory evoked potentials during anaesthesia with increasing endexpiratory concentrations of desflurane. Schwender, D., Klasing, S., Conzen, P., Finsterer, U., Pöppel, E., Peter, K. Acta anaesthesiologica Scandinavica. (1996) [Pubmed]
  12. Change in cerebral blood flow velocity with onset of EEG silence during inhalation anesthesia in humans: evidence of flow-metabolism coupling? Lam, A.M., Matta, B.F., Mayberg, T.S., Strebel, S. J. Cereb. Blood Flow Metab. (1995) [Pubmed]
  13. Fluorinated anesthetic exposure "activates" the renal cortical sphingomyelinase cascade. Lochhead, K.M., Zager, R.A. Kidney Int. (1998) [Pubmed]
  14. Sevoflurane. A review of its pharmacodynamic and pharmacokinetic properties and its clinical use in general anaesthesia. Patel, S.S., Goa, K.L. Drugs (1996) [Pubmed]
  15. Desflurane. A review of its pharmacodynamic and pharmacokinetic properties and its efficacy in general anaesthesia. Patel, S.S., Goa, K.L. Drugs (1995) [Pubmed]
  16. Preservation of hypoxic pulmonary vasoconstriction during sevoflurane and desflurane anesthesia compared to the conscious state in chronically instrumented dogs. Lesitsky, M.A., Davis, S., Murray, P.A. Anesthesiology (1998) [Pubmed]
  17. Desflurane confers neurologic protection for deep hypothermic circulatory arrest in newborn pigs. Kurth, C.D., Priestley, M., Watzman, H.M., McCann, J., Golden, J. Anesthesiology (2001) [Pubmed]
  18. Isoflurane and desflurane impair right ventricular-pulmonary arterial coupling in dogs. Kerbaul, F., Rondelet, B., Motte, S., Fesler, P., Hubloue, I., Ewalenko, P., Naeije, R., Brimioulle, S. Anesthesiology (2004) [Pubmed]
  19. The risk of myocardial ischemia in patients receiving desflurane versus sufentanil anesthesia for coronary artery bypass graft surgery. The S.P.I. Research Group. Helman, J.D., Leung, J.M., Bellows, W.H., Pineda, N., Roach, G.W., Reeves, J.D., Howse, J., McEnany, M.T., Mangano, D.T. Anesthesiology (1992) [Pubmed]
  20. Role of the beta1-adrenergic pathway in anesthetic and ischemic preconditioning against myocardial infarction in the rabbit heart in vivo. Lange, M., Smul, T.M., Blomeyer, C.A., Redel, A., Klotz, K.N., Roewer, N., Kehl, F. Anesthesiology (2006) [Pubmed]
  21. Desflurane clinical pharmacokinetics and pharmacodynamics. Caldwell, J.E. Clinical pharmacokinetics. (1994) [Pubmed]
  22. Induction and maintenance characteristics of anesthesia with desflurane and nitrous oxide in infants and children. Zwass, M.S., Fisher, D.M., Welborn, L.G., Coté, C.J., Davis, P.J., Dinner, M., Hannallah, R.S., Liu, L.M., Sarner, J., McGill, W.A. Anesthesiology (1992) [Pubmed]
  23. Desflurane and isoflurane increase lumbar cerebrospinal fluid pressure in normocapnic patients undergoing transsphenoidal hypophysectomy. Talke, P., Caldwell, J., Dodsont, B., Richardson, C.A. Anesthesiology (1996) [Pubmed]
  24. The effect of pyrogen administration on sweating and vasoconstriction thresholds during desflurane anesthesia. Lenhardt, R., Negishi, C., Sessler, D.I., Ozaki, M., Ettinger, K., Bastanmehr, H., Lobo, E. Anesthesiology (1999) [Pubmed]
  25. Influence of volatile anesthetics on left ventricular afterload in vivo. Differences between desflurane and sevoflurane. Lowe, D., Hettrick, D.A., Pagel, P.S., Warltier, D.C. Anesthesiology (1996) [Pubmed]
  26. Myocardial effects of desflurane in hamsters with hypertrophic cardiomyopathy. Vivien, B., Hanouz, J.L., Gueugniaud, P.Y., Lecarpentier, Y., Coriat, P., Riou, B. Anesthesiology (1998) [Pubmed]
  27. Sympathetic nervous system activation and hyperdynamic circulation associated with desflurane: not all isomers are created equal. Lowenstein, E. Anesthesiology (1993) [Pubmed]
  28. The effect of desflurane and isoflurane on cerebrospinal fluid pressure in humans with supratentorial mass lesions. Muzzi, D.A., Losasso, T.J., Dietz, N.M., Faust, R.J., Cucchiara, R.F., Milde, L.N. Anesthesiology (1992) [Pubmed]
  29. Effects of prophylactic nalmefene on the incidence of morphine-related side effects in patients receiving intravenous patient-controlled analgesia. Joshi, G.P., Duffy, L., Chehade, J., Wesevich, J., Gajraj, N., Johnson, E.R. Anesthesiology (1999) [Pubmed]
  30. Mass spectrometry provides warning of carbon monoxide exposure via trifluoromethane. Woehick, H.J., Dunning, M., Nithipatikom, K., Kulier, A.H., Henry, D.W. Anesthesiology (1996) [Pubmed]
  31. Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration. Rampil, I.J., Lockhart, S.H., Zwass, M.S., Peterson, N., Yasuda, N., Eger, E.I., Weiskopf, R.B., Damask, M.C. Anesthesiology (1991) [Pubmed]
  32. Desflurane differentially affects the release of proinflammatory cytokines in plasma and bronchoalveolar fluid of endotoxemic rats. Boost, K.A., Hofstetter, C., Flondor, M., Betz, C., Homann, M., Pfeilschifter, J., Muehl, H., Zwissler, B. Int. J. Mol. Med. (2006) [Pubmed]
  33. TOK1 is a volatile anesthetic stimulated K+ channel. Gray, A.T., Winegar, B.D., Leonoudakis, D.J., Forsayeth, J.R., Yost, C.S. Anesthesiology (1998) [Pubmed]
  34. The in vitro effect of desflurane preconditioning on endothelial adhesion molecules and mRNA expression. Biao, Z., Zhanggang, X., Hao, J., Changhong, M., Jing, C. Anesth. Analg. (2005) [Pubmed]
  35. The effect of three inhaled anesthetics in mice harboring mutations in the GluR6 (kainate) receptor gene. Sonner, J.M., Vissel, B., Royle, G., Maurer, A., Gong, D., Baron, N.V., Harrison, N., Fanselow, M., Eger, E.I. Anesth. Analg. (2005) [Pubmed]
  36. Does the use of electroencephalographic bispectral index or auditory evoked potential index monitoring facilitate recovery after desflurane anesthesia in the ambulatory setting? White, P.F., Ma, H., Tang, J., Wender, R.H., Sloninsky, A., Kariger, R. Anesthesiology (2004) [Pubmed]
  37. Use of desflurane for outpatient anesthesia. A comparison with propofol and nitrous oxide. Van Hemelrijck, J., Smith, I., White, P.F. Anesthesiology (1991) [Pubmed]
  38. Desflurane as a marker of limb-to-systemic leak during hyperthermic isolated limb perfusion. Stanley, G., Sundarakumaran, R., Crowley, R., Kavanah, M. Anesthesiology (2000) [Pubmed]
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