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MeSH Review

Goiter, Endemic

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Disease relevance of Goiter, Endemic


High impact information on Goiter, Endemic


Chemical compound and disease context of Goiter, Endemic

  • Thyroid hormone and immunological studies in endemic goiter [10].
  • Evidence that cassava ingestion increases thiocyanate formation: a possible etiologic factor in endemic goiter [11].
  • In this area, endemic goiter associated with moderate iodine deficiency [59 +/- 3 (+/- SE) microgram iodine/g creatinine], as defined by WHO criteria, affects 65% of the population [12].
  • All Graves' IgG that stimulated [3H]thymidine incorporation in FRTL-5 cells also stimulated cAMP production in this culture system, whereas no adenylate cyclase stimulation was produced by IgG from patients with endemic goiter [9].
  • Lactate dehydrogenase activity, a marker of cytosolic enzyme, was not lower in endemic goiter tissues than in normal tissues, suggesting that both tissues possessed functioning cells capable of producing cytosolic enzyme [13].

Biological context of Goiter, Endemic


Gene context of Goiter, Endemic


Analytical, diagnostic and therapeutic context of Goiter, Endemic


  1. Endemic goiter in Vietnam. Hershman, J.M., Due, D.T., Sharp, B., My, L., Kent, J.R., Binh, L.N., Reed, A.W., Phuc, L.D., Van Herle, A.J., Thai, N.A., Troung, T.X., Van, N.V., Sugawara, M., Pekary, A.E. J. Clin. Endocrinol. Metab. (1983) [Pubmed]
  2. Iodide-induced thyrotoxicosis. Fradkin, J.E., Wolff, J. Medicine (Baltimore) (1983) [Pubmed]
  3. Clinical picture of endemic cretinism in central Apennines (Montefeltro). Donati, L., Antonelli, A., Bertoni, F., Moscogiuri, D., Andreani, M., Venturi, S., Filippi, T., Gasperini, L., Neri, S., Baschieri, L. Thyroid (1992) [Pubmed]
  4. Utilization of fine-needle aspiration in patients undergoing thyroidectomy at two academic centers across the Atlantic. Chen, H., Dudley, N.E., Westra, W.H., Sadler, G.P., Udelsman, R. World journal of surgery. (2003) [Pubmed]
  5. The effect of hepatic enzyme-inducing drugs on thyroid hormones and the thyroid gland. Curran, P.G., DeGroot, L.J. Endocr. Rev. (1991) [Pubmed]
  6. The effects of vitamin A deficiency and vitamin A supplementation on thyroid function in goitrous children. Zimmermann, M.B., Wegmüller, R., Zeder, C., Chaouki, N., Torresani, T. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  7. Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Côte d'Ivoire. Zimmermann, M., Adou, P., Torresani, T., Zeder, C., Hurrell, R. Am. J. Clin. Nutr. (2000) [Pubmed]
  8. Randomized, double blind, placebo-controlled trial of low dose iodide in endemic goiter. Kahaly, G., Dienes, H.P., Beyer, J., Hommel, G. J. Clin. Endocrinol. Metab. (1997) [Pubmed]
  9. Failure to detect thyroid growth-promoting activity in immunoglobulin G of patients with endemic goiter. Vitti, P., Chiovato, L., Tonacchera, M., Bendinelli, G., Mammoli, C., Capaccioli, A., Fiore, E., Pretell, E., Pinchera, A. J. Clin. Endocrinol. Metab. (1994) [Pubmed]
  10. Thyroid hormone and immunological studies in endemic goiter. Boukis, M.A., Koutras, D.A., Souvatzoglou, A., Evangelopoulou, A., Vrontakis, M., Moulopoulos, S.D. J. Clin. Endocrinol. Metab. (1983) [Pubmed]
  11. Evidence that cassava ingestion increases thiocyanate formation: a possible etiologic factor in endemic goiter. Bourdoux, P., Delange, F., Gerard, M., Mafuta, M., Hanson, A., Ermans, A.M. J. Clin. Endocrinol. Metab. (1978) [Pubmed]
  12. Goiter size and thyroid function in an endemic goiter area in northern Italy. Roti, E., Gardini, E., D'Amato, L., Salvi, M., Robuschi, G., Manfredi, A., Dallara, G., Pino, S., Guazzi, A.M., Gnudi, A. J. Clin. Endocrinol. Metab. (1986) [Pubmed]
  13. Deficiency of superoxide dismutase in endemic goiter tissue. Sugawara, M., Kita, T., Lee, E.D., Takamatsu, J., Hagen, G.A., Kuma, K., Medeiros-Neto, G.A. J. Clin. Endocrinol. Metab. (1988) [Pubmed]
  14. Thyroglobulin exon 10 gene point mutation in a patient with endemic goiter. Pérez-Centeno, C., González-Sarmiento, R., Mories, M.T., Corrales, J.J., Miralles-García, J.M. Thyroid (1996) [Pubmed]
  15. Hormonal and nutritional status: critical conditions for endemic goiter epidemiology? Ingenbleek, Y., De Visscher, M. Metab. Clin. Exp. (1979) [Pubmed]
  16. Circadian and circannual variations of thyroid function in children 11 +/- 1.5 years of age with and without endemic goiter. Nicolau, G.Y., Dumitriu, L., Plinga, L., Petrescu, E., Sackett-Lundeen, L., Lakatua, D.J., Haus, E. Prog. Clin. Biol. Res. (1987) [Pubmed]
  17. The relationship between autoimmune thyroid disease and iodine intake: a review. Foley, T.P. Endokrynologia Polska. (1992) [Pubmed]
  18. Thyroid peroxidase in endemic goiter tissue. Sugawara, M., Summer, C.N., Kobayashi, A., Murakami, S., Kuma, K., Medeiros-Neto, G.A. J. Endocrinol. Invest. (1990) [Pubmed]
  19. TSH secretion and regulation in endemic goiter and endemic cretinism. Medeiros-Neto, G. Prog. Clin. Biol. Res. (1983) [Pubmed]
  20. Parathormone and calcitonin secretion in endemic goiter. Gozariu, L., Dumitru, E., Florescu, O., Vlăduţiu, T., Duncea, I., Barabaş, E., Juncan, D. Endocrinologie. (1989) [Pubmed]
  21. Minimally invasive open parathyroidectomy in an endemic goiter area: a prospective study. Prager, G., Czerny, C., Kurtaran, A., Passler, C., Scheuba, C., Bieglmayer, C., Niederle, B. Archives of surgery (Chicago, Ill. : 1960) (2001) [Pubmed]
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