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MeSH Review

Coronavirus, Bovine

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Disease relevance of Coronavirus, Bovine


High impact information on Coronavirus, Bovine


Chemical compound and disease context of Coronavirus, Bovine


Biological context of Coronavirus, Bovine


Gene context of Coronavirus, Bovine

  • A second 336 nt ORF, which might encode a leucine-rich protein similar to, but shorter than, the bovine coronavirus internal protein was found within the PEDV N gene [15].
  • The nucleocapsid protein gene of bovine coronavirus is bicistronic [16].
  • We conclude that the bovine coronavirus is comprised of four major structural proteins, gp190 (normally present as 120- and 100-kilodalton subunits), gp140, pp52, and gp26 [10].
  • Neutralizing antigenic domains on bovine coronavirus gp100/E2 were mapped to fragments of this protein by proteolytic cleavage and fragment analysis [17].
  • The sequence of the spike (also called peplomer or E2) protein gene of the Mebus strain of bovine coronavirus (BCV) was obtained from cDNA clones of genomic RNA [18].

Analytical, diagnostic and therapeutic context of Coronavirus, Bovine


  1. Construction of murine coronavirus mutants containing interspecies chimeric nucleocapsid proteins. Peng, D., Koetzner, C.A., McMahon, T., Zhu, Y., Masters, P.S. J. Virol. (1995) [Pubmed]
  2. Expression and secretion of the bovine coronavirus hemagglutinin-esterase glycoprotein by insect cells infected with recombinant baculoviruses. Parker, M.D., Yoo, D., Babiuk, L.A. J. Virol. (1990) [Pubmed]
  3. The hemagglutinin-esterase of mouse hepatitis virus strain S is a sialate-4-O-acetylesterase. Regl, G., Kaser, A., Iwersen, M., Schmid, H., Kohla, G., Strobl, B., Vilas, U., Schauer, R., Vlasak, R. J. Virol. (1999) [Pubmed]
  4. Bovine coronavirus structural proteins. King, B., Brian, D.A. J. Virol. (1982) [Pubmed]
  5. Recognition of N-acetyl-9-O-acetylneuraminic acid by bovine coronavirus and hemagglutinating encephalomyelitis virus. Schultze, B., Herrler, G. Adv. Exp. Med. Biol. (1993) [Pubmed]
  6. Detection of coronavirus RNA and antigen in multiple sclerosis brain. Murray, R.S., Brown, B., Brian, D., Cabirac, G.F. Ann. Neurol. (1992) [Pubmed]
  7. Characterization of the RNA components of a putative molecular switch in the 3' untranslated region of the murine coronavirus genome. Goebel, S.J., Hsue, B., Dombrowski, T.F., Masters, P.S. J. Virol. (2004) [Pubmed]
  8. Identification of a coronavirus hemagglutinin-esterase with a substrate specificity different from those of influenza C virus and bovine coronavirus. Klausegger, A., Strobl, B., Regl, G., Kaser, A., Luytjes, W., Vlasak, R. J. Virol. (1999) [Pubmed]
  9. Replication-defective bovine adenovirus type 3 as an expression vector. Reddy, P.S., Idamakanti, N., Chen, Y., Whale, T., Babiuk, L.A., Mehtali, M., Tikoo, S.K. J. Virol. (1999) [Pubmed]
  10. Antigenic relationships among proteins of bovine coronavirus, human respiratory coronavirus OC43, and mouse hepatitis coronavirus A59. Hogue, B.G., King, B., Brian, D.A. J. Virol. (1984) [Pubmed]
  11. The S protein of bovine coronavirus is a hemagglutinin recognizing 9-O-acetylated sialic acid as a receptor determinant. Schultze, B., Gross, H.J., Brossmer, R., Herrler, G. J. Virol. (1991) [Pubmed]
  12. Bovine coronavirus uses N-acetyl-9-O-acetylneuraminic acid as a receptor determinant to initiate the infection of cultured cells. Schultze, B., Herrler, G. J. Gen. Virol. (1992) [Pubmed]
  13. Application of immunohistochemistry and in situ hybridization for detection of bovine coronavirus in paraffin-embedded, formalin-fixed intestines. Zhang, Z., Andrews, G.A., Chard-Bergstrom, C., Minocha, H.C., Kapil, S. J. Clin. Microbiol. (1997) [Pubmed]
  14. Enteric infections with coronaviruses and toroviruses. Holmes, K.V. Novartis Found. Symp. (2001) [Pubmed]
  15. Sequence determination of the nucleocapsid protein gene of the porcine epidemic diarrhoea virus confirms that this virus is a coronavirus related to human coronavirus 229E and porcine transmissible gastroenteritis virus. Bridgen, A., Duarte, M., Tobler, K., Laude, H., Ackermann, M. J. Gen. Virol. (1993) [Pubmed]
  16. The nucleocapsid protein gene of bovine coronavirus is bicistronic. Senanayake, S.D., Hofmann, M.A., Maki, J.L., Brian, D.A. J. Virol. (1992) [Pubmed]
  17. Mapping of neutralizing epitopes to fragments of the bovine coronavirus E2 protein by proteolysis of antigen-antibody complexes. Deregt, D., Parker, M.D., Cox, G.C., Babiuk, L.A. J. Gen. Virol. (1989) [Pubmed]
  18. Deduced sequence of the bovine coronavirus spike protein and identification of the internal proteolytic cleavage site. Abraham, S., Kienzle, T.E., Lapps, W., Brian, D.A. Virology (1990) [Pubmed]
  19. Comparative sequence analysis of a polymorphic region of the spike glycoprotein S1 subunit of enteric bovine coronavirus isolates. Rekik, M.R., Dea, S. Arch. Virol. (1994) [Pubmed]
  20. Cross-protection studies between respiratory and calf diarrhea and winter dysentery coronavirus strains in calves and RT-PCR and nested PCR for their detection. Cho, K.O., Hasoksuz, M., Nielsen, P.R., Chang, K.O., Lathrop, S., Saif, L.J. Arch. Virol. (2001) [Pubmed]
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