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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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High impact information on Myography

  • Using wire myography, concentration response curves to angiotensin I (AI) and AII were constructed in the presence of 1) vehicle, 2) chymostatin [an inhibitor of chymase], 3) enalaprilat, and 4) the combination of chymostatin and enalaprilat [1].
  • We performed a double-blind, placebo-controlled, cross-over trial comparing insulin sensitivity (measured by the euglycemic hyperinsulinemic clamp) and vascular insulin action (measured by small vessel wire myography) in young healthy males allocated to placebo or 1 mg dexamethasone twice daily for 6 d, each in random order [2].
  • Microvascular function was studied by wire myography, by measuring the concentration response curve to norepinephrine (NE) before and after incubation with insulin (100 and 1,000 pM) [3].
  • The density of ET-1 receptor subtypes in the aorta and vascular structural changes in the mesenteric arterioles (100 to 200 microm ID) were also measured with autoradiography and myography, respectively [4].
  • Measurements of wall morphology and functional responses to serotonin and KCl were assessed with wire myography [5].

Biological context of Myography


Anatomical context of Myography


Associations of Myography with chemical compounds


Gene context of Myography

  • Therefore, UII-mediated contractile responses of aortic ring preparations in wire myography and rat UT (rUT) receptor internalization and intracellular trafficking in binding and imaging analyses were compared [14].
  • Acoustic myography may therefore be a useful non-invasive monitor of force during early fatiguing activity using the present protocol but the need to study AMG during fatigue of different muscles and force levels is stressed [15].
  • Here, we have studied the consequences of extracellular glucose level changes on these effects triggered by elastin peptides (10(-4)-10(-3) mg ml(-1)), on 6- and 30-month-old rats, using the tension myography and the patch-clamp techniques [16].

Analytical, diagnostic and therapeutic context of Myography


  1. Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease. Petrie, M.C., Padmanabhan, N., McDonald, J.E., Hillier, C., Connell, J.M., McMurray, J.J. J. Am. Coll. Cardiol. (2001) [Pubmed]
  2. Glucocorticoids and insulin sensitivity: dissociation of insulin's metabolic and vascular actions. Perry, C.G., Spiers, A., Cleland, S.J., Lowe, G.D., Petrie, J.R., Connell, J.M. J. Clin. Endocrinol. Metab. (2003) [Pubmed]
  3. Altered vascular function in young women with polycystic ovary syndrome. Kelly, C.J., Speirs, A., Gould, G.W., Petrie, J.R., Lyall, H., Connell, J.M. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  4. Blockade of angiotensin II type 1 receptor and not of endothelin receptor prevents hypertension and cardiovascular disease in transgenic (mREN2)27 rats via adrenocortical steroid-independent mechanisms. Rossi, G.P., Sacchetto, A., Rizzoni, D., Bova, S., Porteri, E., Mazzocchi, G., Belloni, A.S., Bahcelioglu, M., Nussdorfer, G.G., Pessina, A.C. Arterioscler. Thromb. Vasc. Biol. (2000) [Pubmed]
  5. Confocal microscopic characterization of a lesion in a cerebral vessel of the stroke-prone spontaneously hypertensive rat. Arribas, S.M., Gordon, J.F., Daly, C.J., Dominiczak, A.F., McGrath, J.C. Stroke (1996) [Pubmed]
  6. Non-esterified fatty acids impair endothelium-dependent vasodilation in rat mesenteric resistance vessels. Sainsbury, C.A., Sattar, N., Connell, J.M., Hillier, C., Petrie, J.R. Clin. Sci. (2004) [Pubmed]
  7. Further characterization of the time-dependent vascular effects of delta9-tetrahydrocannabinol. O'Sullivan, S.E., Kendall, D.A., Randall, M.D. J. Pharmacol. Exp. Ther. (2006) [Pubmed]
  8. Neomycin inhibits K+-induced force and Ca2+ channel current in rat arterial smooth muscle. Langton, P.D., Farley, R., Everitt, D.E. Pflugers Arch. (1996) [Pubmed]
  9. Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism. Griffin, S.A., Brown, W.C., MacPherson, F., McGrath, J.C., Wilson, V.G., Korsgaard, N., Mulvany, M.J., Lever, A.F. Hypertension (1991) [Pubmed]
  10. Glycine rectifies vascular dysfunction induced by dietary protein imbalance during pregnancy. Brawley, L., Torrens, C., Anthony, F.W., Itoh, S., Wheeler, T., Jackson, A.A., Clough, G.F., Poston, L., Hanson, M.A. J. Physiol. (Lond.) (2004) [Pubmed]
  11. Propionate-induced relaxation in rat mesenteric arteries: a role for endothelium-derived hyperpolarising factor. Knock, G., Psaroudakis, D., Abbot, S., Aaronson, P.I. J. Physiol. (Lond.) (2002) [Pubmed]
  12. Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism. Orie, N.N., Fry, C.H., Clapp, L.H. Cardiovasc. Res. (2006) [Pubmed]
  13. Hiv Tat protein causes endothelial dysfunction in porcine coronary arteries. Paladugu, R., Fu, W., Conklin, B.S., Lin, P.H., Lumsden, A.B., Yao, Q., Chen, C. J. Vasc. Surg. (2003) [Pubmed]
  14. Arrestin-independent internalization and recycling of the urotensin receptor contribute to long-lasting urotensin II-mediated vasoconstriction. Giebing, G., Tölle, M., Jürgensen, J., Eichhorst, J., Furkert, J., Beyermann, M., Neuschäfer-Rube, F., Rosenthal, W., Zidek, W., van der Giet, M., Oksche, A. Circ. Res. (2005) [Pubmed]
  15. Acoustic myography of the human quadriceps muscle during intermittent fatiguing activity. Dalton, P.A., Comerford, M.J., Stokes, M.J. J. Neurol. Sci. (1992) [Pubmed]
  16. The age-dependent vasodilatation and endothelial calcium influx induced by elastin peptides are modulated by extracellular glucose level. Faury, G., Robert, L., Verdetti, J. Biomed. Pharmacother. (2003) [Pubmed]
  17. Cyclosporine treatment preserves coronary resistance artery function in rat cardiac allografts. Moien-Afshari, F., Choy, J.C., McManus, B.M., Laher, I. J. Heart Lung Transplant. (2004) [Pubmed]
  18. Comparison of evoked electromyography and mechanical activity during vecuronium-induced neuromuscular blockade. Mortier, E., Moulaert, P., de Somer, A., Rolly, G. European journal of anaesthesiology. (1988) [Pubmed]
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