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MeSH Review

Dysthymic Disorder

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Psychiatry related information on Dysthymic Disorder


High impact information on Dysthymic Disorder

  • OBJECTIVE: To determine if maintenance therapy with sertraline hydrochloride can effectively prevent recurrence of depression in the high-risk group of patients experiencing chronic major depression or major depression with antecedent dysthymic disorder ("double depression") [6].
  • We assessed the efficacy of lithium carbonate in the treatment of 457 male alcoholics in a double-blind, placebo-controlled Department of Veterans Affairs Cooperative Study. Alcoholics either without depression or with a history of major depression, current major depression, or dysthymic disorder were studied [7].
  • Risk of relapse into an affective episode was high in the months immediately after recovery from a major depressive disorder (MDD) in 141 subjects with nonbipolar depression, without a preexisting dysthymic disorder [8].
  • Six BDNF polymorphisms were genotyped in 258 trios having juvenile probands with childhood-onset DSM-IV major depressive or dysthymic disorder [9].
  • Low testosterone levels in elderly men with dysthymic disorder [10].

Chemical compound and disease context of Dysthymic Disorder


Gene context of Dysthymic Disorder


Analytical, diagnostic and therapeutic context of Dysthymic Disorder


  1. Depressive disorders in childhood. II. A longitudinal study of the risk for a subsequent major depression. Kovacs, M., Feinberg, T.L., Crouse-Novak, M., Paulauskas, S.L., Pollock, M., Finkelstein, R. Arch. Gen. Psychiatry (1984) [Pubmed]
  2. Childhood-onset dysthymic disorder. Clinical features and prospective naturalistic outcome. Kovacs, M., Akiskal, H.S., Gatsonis, C., Parrone, P.L. Arch. Gen. Psychiatry (1994) [Pubmed]
  3. The dexamethasone suppression test in adolescent psychiatric inpatients. Targum, S.D., Capodanno, A.E. The American journal of psychiatry. (1983) [Pubmed]
  4. Depression in epilepsy: prevalence, clinical semiology, pathogenic mechanisms, and treatment. Kanner, A.M. Biol. Psychiatry (2003) [Pubmed]
  5. Prevalence of depressive and anxiety disorders in an assisted reproductive technique clinic. Chen, T.H., Chang, S.P., Tsai, C.F., Juang, K.D. Hum. Reprod. (2004) [Pubmed]
  6. Maintenance phase efficacy of sertraline for chronic depression: a randomized controlled trial. Keller, M.B., Kocsis, J.H., Thase, M.E., Gelenberg, A.J., Rush, A.J., Koran, L., Schatzberg, A., Russell, J., Hirschfeld, R., Klein, D., McCullough, J.P., Fawcett, J.A., Kornstein, S., LaVange, L., Harrison, W. JAMA (1998) [Pubmed]
  7. Lithium treatment of depressed and nondepressed alcoholics. Dorus, W., Ostrow, D.G., Anton, R., Cushman, P., Collins, J.F., Schaefer, M., Charles, H.L., Desai, P., Hayashida, M., Malkerneker, U. JAMA (1989) [Pubmed]
  8. Predictors of relapse in major depressive disorder. Keller, M.B., Lavori, P.W., Lewis, C.E., Klerman, G.L. JAMA (1983) [Pubmed]
  9. Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample. Strauss, J., Barr, C.L., George, C.J., Devlin, B., Vetró, A., Kiss, E., Baji, I., King, N., Shaikh, S., Lanktree, M., Kovacs, M., Kennedy, J.L. Mol. Psychiatry (2005) [Pubmed]
  10. Low testosterone levels in elderly men with dysthymic disorder. Seidman, S.N., Araujo, A.B., Roose, S.P., Devanand, D.P., Xie, S., Cooper, T.B., McKinlay, J.B. The American journal of psychiatry. (2002) [Pubmed]
  11. Neuroendocrine and personality variables in dysthymic disorder. Roy, A., Sutton, M., Pickar, D. The American journal of psychiatry. (1985) [Pubmed]
  12. Relation between lymphocyte beta-adrenergic responsivity and the severity of depressive disorders. Mazzola-Pomietto, P., Azorin, J.M., Tramoni, V., Jeanningros, R. Biol. Psychiatry (1994) [Pubmed]
  13. Free tryptophan response to intravenous insulin in depressed patients. Menna-Perper, M., Swartzburg, M., Mueller, P.S., Rochford, J., Manowitz, P. Biol. Psychiatry (1983) [Pubmed]
  14. Fluoxetine treatment of dysthymia in the elderly. Nobler, M.S., Devanand, D.P., Kim, M.K., Fitzsimons, L.M., Singer, T.M., Turret, N., Sackeim, H.A., Roose, S.P. The Journal of clinical psychiatry. (1996) [Pubmed]
  15. Ritanserin, imipramine, and placebo in the treatment of dysthymic disorder. Bakish, D., Lapierre, Y.D., Weinstein, R., Klein, J., Wiens, A., Jones, B., Horn, E., Browne, M., Bourget, D., Blanchard, A. Journal of clinical psychopharmacology. (1993) [Pubmed]
  16. Bupropion sustained release in adolescents with comorbid attention-deficit/hyperactivity disorder and depression. Daviss, W.B., Bentivoglio, P., Racusin, R., Brown, K.M., Bostic, J.Q., Wiley, L. Journal of the American Academy of Child and Adolescent Psychiatry. (2001) [Pubmed]
  17. The differential ACTH responses to combined dexamethasone/CRH administration in major depressive and dysthymic disorders. Oshima, A., Yamashita, S., Owashi, T., Murata, T., Tadokoro, C., Miyaoka, H., Kamijima, K., Higuchi, T. Journal of psychiatric research. (2000) [Pubmed]
  18. 5-HT2 receptor antagonism in dysthymic disorder: a double-blind placebo-controlled study with ritanserin. Bersani, G., Pozzi, F., Marini, S., Grispini, A., Pasini, A., Ciani, N. Acta psychiatrica Scandinavica. (1991) [Pubmed]
  19. Psychiatric disorder among boys with Duchenne muscular dystrophy. Fitzpatrick, C., Barry, C., Garvey, C. Developmental medicine and child neurology. (1986) [Pubmed]
  20. Treatment outcome validation of DSM-III depressive subtypes. Clinical usefulness in outpatients with mild to moderate depression. Stewart, J.W., McGrath, P.J., Liebowitz, M.R., Harrison, W., Quitkin, F., Rabkin, J.G. Arch. Gen. Psychiatry (1985) [Pubmed]
  21. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. McLeod, M.N., Gaynes, B.N., Golden, R.N. The Journal of clinical psychiatry. (1999) [Pubmed]
  22. Xanthurenic acid flow in 24-hour urine following L-tryptophan loading in depressive patients. Maes, M., De Ruyter, M., Suy, E. Acta psychiatrica Belgica. (1986) [Pubmed]
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