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MeSH Review

Conduct Disorder

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Disease relevance of Conduct Disorder

  • RESULTS: Fewer Black and South Asian male prisoners reported childhood traumas and conduct disorder, and fewer Black prisoners experienced stressful prison experiences, than White prisoners [1].
  • These results suggest that TS, ADHD, stuttering oppositional defiant and conduct disorder, and other behaviors associated with TS, are polygenic, due in part to these three dopaminergic genes, and that the genetics of other polygenic psychiatric disorders may be deciphered using this technique [2].
  • Further, comorbidity of ADHD with conduct disorder (CD) and tic disorder (Tic) is quite common but not yet fully understood [3].

Psychiatry related information on Conduct Disorder


High impact information on Conduct Disorder


Chemical compound and disease context of Conduct Disorder


Biological context of Conduct Disorder


Anatomical context of Conduct Disorder


Gene context of Conduct Disorder


Analytical, diagnostic and therapeutic context of Conduct Disorder


  1. Ethnic differences in prisoners. 2: risk factors and psychiatric service use. Coid, J., Petruckevitch, A., Bebbington, P., Brugha, T., Bhugra, D., Jenkins, R., Farrell, M., Lewis, G., Singleton, N. The British journal of psychiatry : the journal of mental science. (2002) [Pubmed]
  2. Polygenic inheritance of Tourette syndrome, stuttering, attention deficit hyperactivity, conduct, and oppositional defiant disorder: the additive and subtractive effect of the three dopaminergic genes--DRD2, D beta H, and DAT1. Comings, D.E., Wu, S., Chiu, C., Ring, R.H., Gade, R., Ahn, C., MacMurray, J.P., Dietz, G., Muhleman, D. Am. J. Med. Genet. (1996) [Pubmed]
  3. Comorbidity in ADHD-children: effects of coexisting conduct disorder or tic disorder on event-related brain potentials in an auditory selective-attention task. Rothenberger, A., Banaschewski, T., Heinrich, H., Moll, G.H., Schmidt, M.H., van't Klooster, B. European archives of psychiatry and clinical neuroscience. (2000) [Pubmed]
  4. Children with prepubertal-onset major depressive disorder and anxiety grown up. Weissman, M.M., Wolk, S., Wickramaratne, P., Goldstein, R.B., Adams, P., Greenwald, S., Ryan, N.D., Dahl, R.E., Steinberg, D. Arch. Gen. Psychiatry (1999) [Pubmed]
  5. Psychiatric comorbidity in adult attention deficit hyperactivity disorder: findings from multiplex families. McGough, J.J., Smalley, S.L., McCracken, J.T., Yang, M., Del'Homme, M., Lynn, D.E., Loo, S. The American journal of psychiatry. (2005) [Pubmed]
  6. Psychopathology risk transmission in children of parents with substance use disorders. Clark, D.B., Cornelius, J., Wood, D.S., Vanyukov, M. The American journal of psychiatry. (2004) [Pubmed]
  7. Comorbidity of substance abuse and other psychiatric disorders in adolescents. Bukstein, O.G., Brent, D.A., Kaminer, Y. The American journal of psychiatry. (1989) [Pubmed]
  8. Misdiagnosed bipolar disorder in adolescents in a special educational school and treatment program. Isaac, G. The Journal of clinical psychiatry. (1992) [Pubmed]
  9. Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder. Foley, D.L., Eaves, L.J., Wormley, B., Silberg, J.L., Maes, H.H., Kuhn, J., Riley, B. Arch. Gen. Psychiatry (2004) [Pubmed]
  10. Association between self-reported childhood sexual abuse and adverse psychosocial outcomes: results from a twin study. Nelson, E.C., Heath, A.C., Madden, P.A., Cooper, M.L., Dinwiddie, S.H., Bucholz, K.K., Glowinski, A., McLaughlin, T., Dunne, M.P., Statham, D.J., Martin, N.G. Arch. Gen. Psychiatry (2002) [Pubmed]
  11. Decreased cortisol levels in adolescent girls with conduct disorder. Pajer, K., Gardner, W., Rubin, R.T., Perel, J., Neal, S. Arch. Gen. Psychiatry (2001) [Pubmed]
  12. A double-blind placebo-controlled study of lithium in hospitalized aggressive children and adolescents with conduct disorder. Malone, R.P., Delaney, M.A., Luebbert, J.F., Cater, J., Campbell, M. Arch. Gen. Psychiatry (2000) [Pubmed]
  13. Clinical efficacy of methylphenidate in conduct disorder with and without attention deficit hyperactivity disorder. Klein, R.G., Abikoff, H., Klass, E., Ganeles, D., Seese, L.M., Pollack, S. Arch. Gen. Psychiatry (1997) [Pubmed]
  14. Behavioral efficacy of haloperidol and lithium carbonate. A comparison in hospitalized aggressive children with conduct disorder. Campbell, M., Small, A.M., Green, W.H., Jennings, S.J., Perry, R., Bennett, W.G., Anderson, L. Arch. Gen. Psychiatry (1984) [Pubmed]
  15. Biochemical differences in children with conduct disorder socialized and undersocialized. Rogeness, G.A., Hernandez, J.M., Macedo, C.A., Mitchell, E.L. The American journal of psychiatry. (1982) [Pubmed]
  16. Two dopamine genes related to reports of childhood retrospective inattention and conduct disorder symptoms. Rowe, D.C., Stever, C., Chase, D., Sherman, S., Abramowitz, A., Waldman, I.D. Mol. Psychiatry (2001) [Pubmed]
  17. Adrenal androgens and aggression in conduct disorder prepubertal boys and normal controls. van Goozen, S.H., Matthys, W., Cohen-Kettenis, P.T., Thijssen, J.H., van Engeland, H. Biol. Psychiatry (1998) [Pubmed]
  18. Serum cholesterol in aggressive conduct disorder: a preliminary study. Virkkunen, M., Penttinen, H. Biol. Psychiatry (1984) [Pubmed]
  19. Response to emotional stimuli in boys with conduct disorder. Herpertz, S.C., Mueller, B., Qunaibi, M., Lichterfeld, C., Konrad, K., Herpertz-Dahlmann, B. The American journal of psychiatry. (2005) [Pubmed]
  20. Genetic effects on the variation and covariation of attention deficit-hyperactivity disorder (ADHD) and oppositional-defiant disorder/conduct disorder (Odd/CD) symptomatologies across informant and occasion of measurement. Nadder, T.S., Rutter, M., Silberg, J.L., Maes, H.H., Eaves, L.J. Psychological medicine. (2002) [Pubmed]
  21. Differences in heart rate and blood pressure in children with conduct disorder, major depression, and separation anxiety. Rogeness, G.A., Cepeda, C., Macedo, C.A., Fischer, C., Harris, W.R. Psychiatry research. (1990) [Pubmed]
  22. P300 event-related potential amplitude and impulsivity in cocaine-dependent subjects. Moeller, F.G., Barratt, E.S., Fischer, C.J., Dougherty, D.M., Reilly, E.L., Mathias, C.W., Swann, A.C. Neuropsychobiology (2004) [Pubmed]
  23. Dehydroepiandrosterone sulphate and corticotropin levels are high in young male patients with conduct disorder: comparisons for growth factors, thyroid and gonadal hormones. Dmitrieva, T.N., Oades, R.D., Hauffa, B.P., Eggers, C. Neuropsychobiology (2001) [Pubmed]
  24. Measurement of cortisol and lymphocyte subpopulations in depressed and conduct-disordered adolescents. Targum, S.D., Clarkson, L.L., Magac-Harris, K., Marshall, L.E., Skwerer, R.G. Journal of affective disorders. (1990) [Pubmed]
  25. Gene-environment interaction in hyperkinetic conduct disorder (HD + CD) as indicated by season of birth variations in dopamine receptor (DRD4) gene polymorphism. Seeger, G., Schloss, P., Schmidt, M.H., Rüter-Jungfleisch, A., Henn, F.A. Neurosci. Lett. (2004) [Pubmed]
  26. Association of the androgen receptor gene (AR) with ADHD and conduct disorder. Comings, D.E., Chen, C., Wu, S., Muhleman, D. Neuroreport (1999) [Pubmed]
  27. Electroencephalogram and treatment of hospitalized aggressive children with haloperidol or lithium. Bennett, W.G., Korein, J., Kalmijn, M., Grega, D.M., Campbell, M. Biol. Psychiatry (1983) [Pubmed]
  28. Baseline predictors of response to divalproex in conduct disorder. Saxena, K., Silverman, M.A., Chang, K., Khanzode, L., Steiner, H. The Journal of clinical psychiatry. (2005) [Pubmed]
  29. Psychopathology and substance abuse in parents of young children with attention-deficit/hyperactivity disorder. Chronis, A.M., Lahey, B.B., Pelham, W.E., Kipp, H.L., Baumann, B.L., Lee, S.S. Journal of the American Academy of Child and Adolescent Psychiatry. (2003) [Pubmed]
  30. A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder. Connor, D.F., Fletcher, K.E., Swanson, J.M. Journal of the American Academy of Child and Adolescent Psychiatry. (1999) [Pubmed]
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