The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Hemispherectomy


Psychiatry related information on Hemispherectomy


High impact information on Hemispherectomy

  • Bipolar illness after right hemispherectomy. A response to lithium carbonate and carbamazepine [7].
  • In 3 children who had undergone cerebral hemispherectomy (hemidecortication) between the ages of 1 year 5 months and 4 years for the alleviation of intractable epilepsy, cerebral glucose utilization was studied serially with positron emission tomography [8].
  • Three to 7 months after hemispherectomy, glucose utilization in the caudate nuclei on the side of hemispherectomy had decreased to below preoperative values, presumably due to total deprivation of ipsilateral cortical input [8].
  • This study reports on the clinical course and outcomes of 33 children who underwent hemispherectomy at Great Ormond Street Hospital, London, between 1991 and 1997 [9].
  • The efficacy of PAI in our patient supports the autoimmune hypothesis of RE and suggests its application to avoid, or at least delay, functional hemispherectomy in selected cases [10].

Biological context of Hemispherectomy


Anatomical context of Hemispherectomy

  • The postoperative results of the Cartagena program were compared with those reported at the Second International Palm Desert Conference 1992, which revealed a similar rate of postoperative seizure control in temporal lobe epilepsy, slightly inferior results with hemispherectomy, and slightly better results with anterior callosotomy [12].
  • A detailed study was made of the pathology of specimens removed by hemispherectomy for the treatment of intractable epilepsy in children with unilateral middle cerebral artery stroke [13].
  • It is suggested that both of these measurements must be taken into account when assessing morphological effects upon the neocortex either in human pathology (i.e. hemispherectomy, intractable epilepsy) or in animal models [14].

Associations of Hemispherectomy with chemical compounds


Gene context of Hemispherectomy

  • Performance on the ITPA following cerebral commissurotomy and hemispherectomy [19].
  • The techniques of neuronal disconnection included multiple subpial resection (MST), corpus callosotomy. and functional hemispherectomy by disconnection [20].
  • Unilateral auditory language comprehension on the Token Test following cerebral commissurotomy and hemispherectomy [21].
  • To examine further the relationships between brain function and dreaming, we studied REM sleep dream recall and content in four patients having undergone right functional or anatomical hemispherectomy and eight matched control subjects [22].
  • Recently, we introduced the concept of peri-insular hemispherotomy, a functional hemispherectomy with minimal brain removal (9, 21) [23].

Analytical, diagnostic and therapeutic context of Hemispherectomy


  1. Functional hemispherectomy for treatment of epilepsy associated with hemiplegia: rationale, indications, results, and comparison with callosotomy. Tinuper, P., Andermann, F., Villemure, J.G., Rasmussen, T.B., Quesney, L.F. Ann. Neurol. (1988) [Pubmed]
  2. Chronic encephalitis, epilepsy, and cerebrovascular immune complex deposits. Andrews, J.M., Thompson, J.A., Pysher, T.J., Walker, M.L., Hammond, M.E. Ann. Neurol. (1990) [Pubmed]
  3. Residual sensorimotor functions in a patient after right-sided hemispherectomy. Müller, F., Kunesch, E., Binkofski, F., Freund, H.J. Neuropsychologia. (1991) [Pubmed]
  4. Hemispherectomy for seizures. Bare, M.A. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses. (1989) [Pubmed]
  5. Congenital choroid plexus papilloma: light and electron microscopic study of a case. Di Trapani, G., Di Rocco, C., Lazari, M., Velardi, F., La Cara, A. Italian journal of neurological sciences. (1983) [Pubmed]
  6. Expletives: neurolinguistic and neurobehavioral perspectives on swearing. Van Lancker, D., Cummings, J.L. Brain Res. Brain Res. Rev. (1999) [Pubmed]
  7. Bipolar illness after right hemispherectomy. A response to lithium carbonate and carbamazepine. Forrest, D.V. Arch. Gen. Psychiatry (1982) [Pubmed]
  8. Metabolic recovery in caudate nucleus of children following cerebral hemispherectomy. Chugani, H.T., Jacobs, B. Ann. Neurol. (1994) [Pubmed]
  9. Clinical outcomes of hemispherectomy for epilepsy in childhood and adolescence. Devlin, A.M., Cross, J.H., Harkness, W., Chong, W.K., Harding, B., Vargha-Khadem, F., Neville, B.G. Brain (2003) [Pubmed]
  10. Long-term selective IgG immuno-adsorption improves Rasmussen's encephalitis. Antozzi, C., Granata, T., Aurisano, N., Zardini, G., Confalonieri, P., Airaghi, G., Mantegazza, R., Spreafico, R. Neurology (1998) [Pubmed]
  11. Cortical motor reorganization following early brain damage and hemispherectomy demonstrated by transcranial magnetic stimulation. Kastrup, O., Leonhardt, G., Kurthen, M., Hufnagel, A. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. (2000) [Pubmed]
  12. Comparison of the epilepsy surgery programs in Cartagena, Colombia, and Zürich, Switzerland. Tureczek, I.E., Fandiño-Franky, J., Wieser, H.G. Epilepsia (2000) [Pubmed]
  13. Stroke in the developing brain and intractable epilepsy: effect of timing on hippocampal sclerosis. Squier, W., Salisbury, H., Sisodiya, S. Developmental medicine and child neurology. (2003) [Pubmed]
  14. Regional age-dependent effects of hemineodecortication upon contralateral neocortical thickness: comparison with other measures of cortical size. Schmanke, T.D., Villablanca, J.R. Dev. Neurosci. (1999) [Pubmed]
  15. Bilateral ballistic movements occurring as a late complication of hemispherectomy and responding to sulpiride. Wroe, S., Richens, A., Compston, A. J. Neurol. (1986) [Pubmed]
  16. Thalamic-hypothalamic interrelationships and stress-induced rebounding adrenocortical response in the pigeon. Ramade, F., Bayle, J.D. Neuroendocrinology (1982) [Pubmed]
  17. Technetium-99m HmPAO brain SPECT and outcome of hemispherectomy for intractable seizures. Carmant, L., O'Tuama, L.A., Roach, P.J., Kramer, U., Mikati, M.A., Riviello, J.J., Helmers, S.L., Madsen, J.R., Black, P.M., Lombroso, C.T. Pediatric neurology. (1994) [Pubmed]
  18. Rasmussen encephalitis associated with segmental vitiligo of the scalp: clinicopathologic report. Yacubian, E.M., Rosemberg, S., Garrido Neto, T.L., Marie, S.K., Valério, R.M., Jorge, C.L. J. Child Neurol. (2001) [Pubmed]
  19. Performance on the ITPA following cerebral commissurotomy and hemispherectomy. Zaidel, E. Neuropsychologia. (1979) [Pubmed]
  20. Neuronal disconnection for the surgical treatment of pediatric epilepsy. Shimizu, H., Maehara, T. Epilepsia (2000) [Pubmed]
  21. Unilateral auditory language comprehension on the Token Test following cerebral commissurotomy and hemispherectomy. Zaidel, E. Neuropsychologia. (1977) [Pubmed]
  22. REM sleep dream mentation in right hemispherectomized patients. McCormick, L., Nielsen, T., Ptito, M., Hassainia, F., Ptito, A., Villemure, J.G., Vera, C., Montplaisir, J. Neuropsychologia. (1997) [Pubmed]
  23. Peri-insular hemispherotomy: surgical principles and anatomy. Villemure, J.G., Mascott, C.R. Neurosurgery (1995) [Pubmed]
  24. Enhanced motor cortical excitability in the unaffected hemisphere after hemispherectomy. Shimizu, T., Nariai, T., Maehara, T., Hino, T., Komori, T., Shimizu, H., Hirai, S., Senda, M. Neuroreport (2000) [Pubmed]
  25. Use of recombinant human erythropoietin to avoid blood transfusion in a Jehovah's Witness requiring hemispherectomy. Case report. Schiff, S.J., Weinstein, S.L. J. Neurosurg. (1993) [Pubmed]
WikiGenes - Universities