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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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High impact information on Hippophae

  • The concept was demonstrated for the determination of the antioxidative potential of various polyphenol mixtures and of the methanol extract of the sea buckthorn (Hippophae rhamnoides L.). In most cases quercetin has the highest rate constant of oxidation among the tested phenolic compounds [1].
  • We have also studied the effects of antioxidants such as alpha-tocopherol, ascorbic acid, and juice from sea buckthorn on DHA [2].
  • Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor [3].
  • Under the optimal experimental conditions, analytical capability of the apparatus was successfully demonstrated in separation of flavonoids from a crude sea buckthorn ethanol extract in a multilayer coil with a total capacity of 8 ml [4].
  • The cross-axis synchronous flow-through coil planet centrifuge with a 20-cm revolutional radius and a total capacity of 1600 ml was successfully applied to preparative counter-current chromatography of various biological samples, which include sea buckthorn extract, steroid reaction mixture, indole plant hormones, and dinitrophenylamino acids [5].

Biological context of Hippophae


Associations of Hippophae with chemical compounds


Gene context of Hippophae

  • Ascorbic acid was shown to be the major antioxidant in sea buckthorn juice [14].
  • Addition of ethanol insoluble substances up to 7% (w/v) to the juice changed its rheological behavior to resemble that of a sea buckthorn juice concentrate at 48 degrees Brix, although frequency dependence was unaffected above 1 Hz [15].
  • In groups given a high dosage (6 or 8 ml/kg) intraperitoneally, the level of TBARS (thiobarbituric acid-reactive substances) was decreased significantly (p < 0.05) by the injection of sea buckthorn seed oil, and the activity of GST was increased significantly (p < 0.05) [7].

Analytical, diagnostic and therapeutic context of Hippophae


  1. On-column capillary electrophoretic monitoring of rapid reaction kinetics for determination of the antioxidative potential of various bioactive phenols. Vaher, M., Ehala, S., Kaljurand, M. Electrophoresis (2005) [Pubmed]
  2. Monitoring monohydroperoxides in docosahexaenoic acid using high-performance liquid chromatography. Lyberg, A.M., Adlercreutz, P. Lipids (2006) [Pubmed]
  3. Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor. Padmavathi, B., Upreti, M., Singh, V., Rao, A.R., Singh, R.P., Rath, P.C. Nutrition and cancer. (2005) [Pubmed]
  4. Multilayer coil planet centrifuge for analytical high-speed counter-current chromatography. Oka, H., Oka, F., Ito, Y. J. Chromatogr. (1989) [Pubmed]
  5. Preliminary applications of cross-axis synchronous flow-through coil planet centrifuge for large-scale preparative counter-current chromatography. Zhang, T.Y., Lee, Y.W., Fang, Q.C., Xiao, R., Ito, Y. J. Chromatogr. (1988) [Pubmed]
  6. Changes in triacylglycerol composition during ripening of sea buckthorn (Hippophaë rhamnoides L.) seeds. Tsydendambaev, V.D., Vereshchagin, A.G. J. Agric. Food Chem. (2003) [Pubmed]
  7. Effect of sulfur dioxide inhalation on the glutathione redox system in mice and protective role of sea buckthorn seed oil. Wu, D., Meng, Z. Arch. Environ. Contam. Toxicol. (2003) [Pubmed]
  8. Evaluation of antioxidant activity of leaf extract of Seabuckthorn (Hippophae rhamnoides L.) on chromium(VI) induced oxidative stress in albino rats. Geetha, S., Sai Ram, M., Mongia, S.S., Singh, V., Ilavazhagan, G., Sawhney, R.C. Journal of ethnopharmacology. (2003) [Pubmed]
  9. Isolation of five types of flavonol from seabuckthorn (Hippophae rhamnoides) and induction of apoptosis by some of the flavonols in human promyelotic leukemia HL-60 cells. Hibasami, H., Mitani, A., Katsuzaki, H., Imai, K., Yoshioka, K., Komiya, T. Int. J. Mol. Med. (2005) [Pubmed]
  10. Isolation and characterization of 1,3-dicapryloyl-2-linoleoylglycerol: a novel triglyceride from berries of Hippophae rhamnoides. Swaroop, A., Sinha, A.K., Chawla, R., Arora, R., Sharma, R.K., Kumar, J.K. Chem. Pharm. Bull. (2005) [Pubmed]
  11. Determination of alpha-tocopherol in the Traditional Chinese Medicinal preparation Sea buckthorn oil capsule by non-aqueous reversed phase-HPLC. Luhua, Z., Ying, T., Zhengyu, Z., Guangji, W. Chem. Pharm. Bull. (2004) [Pubmed]
  12. Antioxidant oligomeric proanthocyanidins from sea buckthorn (Hippophae rhamnoides) Pomace. Rösch, D., Mügge, C., Fogliano, V., Kroh, L.W. J. Agric. Food Chem. (2004) [Pubmed]
  13. Effects of different origins and harvesting time on vitamin C, tocopherols, and tocotrienols in sea buckthorn (Hippophaë rhamnoides) berries. Kallio, H., Yang, B., Peippo, P. J. Agric. Food Chem. (2002) [Pubmed]
  14. Structure-antioxidant efficiency relationships of phenolic compounds and their contribution to the antioxidant activity of sea buckthorn juice. Rösch, D., Bergmann, M., Knorr, D., Kroh, L.W. J. Agric. Food Chem. (2003) [Pubmed]
  15. Rheology of sea buckthorn (Hippophae rhamnoides L.) juice. Oomah, B.D., Séry, G., Godfrey, D.V., Beveridge, T.H. J. Agric. Food Chem. (1999) [Pubmed]
  16. Structural investigations of flavonol glycosides from sea buckthorn (Hippophaë rhamnoides) pomace by NMR spectroscopy and HPLC-ESI-MS(n). Rösch, D., Krumbein, A., Mügge, C., Kroh, L.W. J. Agric. Food Chem. (2004) [Pubmed]
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