Disease relevance of Vulvovaginitis

• However, ketoconazole failed to prevent Candida esophagitis and vulvovaginitis in two patients and one patient, respectively [1].
• 3. Women with HIV are more likely to have disease caused by HPV (such as abnormal Pap smears or warts), more severe Candida vulvovaginitis, and PID [2].
• First we identified women with presumed gonorrhea or chlamydia on the basis of a combination of diagnostic codes for cervicitis, vulvovaginitis or Bartholin's abscess, and a computer record of a prescription for doxycycline [3].
• A caprine herpesvirus related to infectious bovine rhinotracheitis virus but immunologically distinct from that virus was isolated from an outbreak of vulvovaginitis in a herd of Saanen goats [4].
• Clinical studies (4 open and 1 double-blind) were performed on 93 women suffering from vulvovaginitis and cervicitis by treatment of 0.134% tetridamine vaginal lavage, two times daily, for 7 days [5].

High impact information on Vulvovaginitis

• Prepubertal gonococcal vulvovaginitis: a penicillin-resistant infection treated with cefotaxime [6].
• The ABO, P1, and Lewis group phenotypes of 35 women with recurrent vulvovaginitis but without other chronic infections were determined [7].
• Vulvovaginitis due to fluconazole resistant Candida albicans following self treatment with non-prescribed triazoles [8].
• Severe vulvovaginitis associated with intravaginal nystatin therapy [9].
• CONCLUSION: The expression of heat shock proteins and IL-10 in the vaginas of women with a history of recurrent vulvovaginitis but not in the vaginas of control subjects suggests the existence of differences in the vaginal milieu between the 2 groups, even when both are without vaginal symptoms [10].

Chemical compound and disease context of Vulvovaginitis

• Efficacy and tolerability of single-dose versus six-day treatment of candidal vulvovaginitis with vaginal tablets of clotrimazole [11].
• These data suggest that vaginal specimens from women who have vulvovaginal symptoms and negative potassium hydroxide wet preparation results should be cultured for fungi before the diagnosis of fungal vulvovaginitis is excluded [12].
• Recurrent allergic vulvovaginitis: treatment with Candida albicans allergen immunotherapy [13].
• Fenticonazole nitrate for treatment of vulvovaginitis: efficacy, safety, and tolerability of 1-gram ovules, administered as ultra-short 2-day regimen [14].
• Systemic treatment of recurrent candidal vulvovaginitis by Itraconazole [15].

Gene context of Vulvovaginitis

• The expression of the 60-kD and 70-kD heat shock proteins (hsp60 and hsp70) in the vaginas of 43 asymptomatic women of reproductive age with or without a history of recurrent vulvovaginitis (RVV) were compared [16].
• The rates of C albicans colonization and vulvovaginitis among immunocompetent (CD4 count at least 500 cells/mm3) HIV-positive women did not differ from those among HIV-negative women [17].
• Sixty per cent of animals developed vulvovaginitis, perigenital alopecia and hind-limb paresia [18].
• Bovine herpesvirus type 1 (BoHV-1) is the causative agent of respiratory and genital tract infections such as infectious rhinotracheitis (IBR), infectious pustular vulvovaginitis (IPV, balanoposthitis (IBP), and abortion [19].
• Prevalence, susceptibility profile and proteinase production of yeasts causing vulvovaginitis in Turkish women [20].

Analytical, diagnostic and therapeutic context of Vulvovaginitis

• Thirty days after treatment completion, 73% of the butoconazole-treated patients and 69% of the miconazole-treated patients remained Candida negative; 78% of the butoconazole-treated patients and 80% of the miconazole-treated patients remained free of clinical symptoms of vulvovaginitis [21].
• Value of Candida polymerase chain reaction and vaginal cytokine analysis for the differential diagnosis of women with recurrent vulvovaginitis [22].
• A study was undertaken in children and adolescents aged 4-18 years on the value of benzydamine vaginal douche in addition to chemotherapy for moderate to severe vulvovaginitis, including those also suffering from insulin-dependent diabetes mellitus (IDDM) [23].

References