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MeSH Review

Cardiac Surgical Procedures

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Disease relevance of Cardiac Surgical Procedures


High impact information on Cardiac Surgical Procedures


Anatomical context of Cardiac Surgical Procedures


Associations of Cardiac Surgical Procedures with chemical compounds


Gene context of Cardiac Surgical Procedures

  • In 1952, John Lewis performed the first successful open heart surgical procedure of any kind, repairing an atrial septal defect under general hypothermia in a 5-year-old girl [15].
  • CONCLUSIONS: In children undergoing reoperative cardiac surgical procedures, aprotinin is effective in attenuating postbypass coagulopathies, decreasing blood product exposure, improving clinical outcome, and reducing patient charges [16].
  • Aprotinin, a bovine protease inhibitor, has been used extensively in patients undergoing cardiac surgical procedures in an effort to minimize blood loss and prevent the complications associated with blood replacement [17].
  • A significant proportion of patients with epicardial lead systems underwent another cardiac surgical procedure at the time of ICD implantation (13.9%) as compared to none in those who had endocardial leads implanted (P < 0.001) [18].
  • Aprotinin is a proteinase inhibitor with antifibrinolytic properties that has found widespread application during cardiac surgical procedures due to its ability to decrease blood loss and transfusion requirements [19].


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  14. Diazepam's effect on systemic vascular resistance during cardiopulmonary bypass is not caused by its vehicle (alcohol-propylene glycol). Jacka, M.J., Johnson, G.D., Milne, B. J. Cardiothorac. Vasc. Anesth. (1993) [Pubmed]
  15. C. Walton and F. John. Shumway, N.E. Ann. Thorac. Surg. (1999) [Pubmed]
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  17. Use of aprotinin in LVAD recipients reduces blood loss, blood use, and perioperative mortality. Goldstein, D.J., Seldomridge, J.A., Chen, J.M., Catanese, K.A., DeRosa, C.M., Weinberg, A.D., Smith, C.R., Rose, E.A., Levin, H.R., Oz, M.C. Ann. Thorac. Surg. (1995) [Pubmed]
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