Disease relevance of Liver Cirrhosis, Experimental

• When exogenous ANP is administered intravenously to dogs or rats with experimental liver cirrhosis and ascites, an heterogeneous natriuretic response is obtained with about half of the population not responding [1].

High impact information on Liver Cirrhosis, Experimental

• Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery [2].
• Melatonin prevents experimental liver cirrhosis induced by thioacetamide in rats [3].
• BACKGROUND/AIMS: Hepatic concentration of endothelin-1 (ET-1) is increased in human and experimental liver cirrhosis [4].
• The present study was undertaken to determine whether a non-peptide arginine vasopressin (AVP) antagonist [5-dimethylamino-1-(4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetra hydro-1H- benzazepine] (OPC-31260) improves the impaired water excretion in rats with experimental liver cirrhosis [5].
• We propose that HO is an essential component in mechanisms that modulate reactivity of the mesenteric circulation in experimental hepatic cirrhosis in rats [6].

Biological context of Liver Cirrhosis, Experimental

• We evaluated the effect of oxidative stress regulation by melatonin on the development of parenchymal destruction and stellate cell activation in experimental liver cirrhosis [3].

Associations of Liver Cirrhosis, Experimental with chemical compounds

• RESULTS: Significantly higher DPP IV activity was found in the sera of rats with experimental liver cirrhosis (39.2 +/- 3.7; mean +/- SD) compared to phenobarbital-treated (11 +/- 4, P < 0.000002) and nontreated (10.9 +/- 0.9, P < 0.000002) rats [7].
• Hemodynamic characterization in experimental liver cirrhosis induced by thioacetamide administration [8].
• Role of prostaglandins and thromboxane in the control of renal hemodynamics in experimental liver cirrhosis [9].
• The influence of an experimental liver cirrhosis upon the metabolism of diazepam and imipramine hydrochloride in the rat [10].
• Significant increases in glycine, alanine, serine, methionine, glutamate, ornithine, phenylalanine, tyrosine, histidine and proline were observed in rats with the resulting experimental liver cirrhosis [11].

Gene context of Liver Cirrhosis, Experimental

• In the present work, we have studied the expression of MTAP in human and experimental liver cirrhosis and hepatocarcinoma [12].
• Rats with experimental liver cirrhosis have increased endothelin-1 (ET-1) plasma concentrations and show a tendency toward sodium and water retention [13].
• Expression and distribution of the prolactin receptor in normal rat liver and in experimental liver cirrhosis [14].
• BACKGROUND: The exogenous administration of Insulin-like Growth Factor-I (IGF-I) induces hepatoprotective and antifibrogenic actions in experimental liver cirrhosis [15].
• The aim of the study was to examine serum DPP IV activity in experimental liver cirrhosis [7].

References