Disease relevance of Southeastern United States

• CONCLUSIONS: Hereditary breast cancer due to mutations in BRCA1 and BRCA2 was a heterogeneous syndrome in the southeastern United States. Most mutations were seen just once, and uncharacterized variants were common and of uncertain clinical significance [1].
• Black Creek Canal (BCC) virus is a newly identified virus associated with hantavirus pulmonary syndrome (HPS) in the southeastern United States. Nucleotide sequences were determined for the complete S and M and partial L genomic segments of a BCC virus isolate [2].

High impact information on Southeastern United States

• Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States [3].
• Epidemiology of IgA nephropathy in central and eastern Kentucky for the period 1975 through 1994. Central Kentucky Region of the Southeastern United States IgA Nephropathy DATABANK Project [4].
• Serum 25-hydroxyvitamin D concentrations in girls aged 4-8 y living in the southeastern United States [5].
• The discovery of LAC virus in wild populations of Ae. albopictus coupled with its expanding distribution in the southeastern United States, suggests that this mosquito may become an important accessory vector, potentially increasing the number of human cases in endemic foci or expanding the range of the disease [6].
• Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study [7].

Biological context of Southeastern United States

• This is the first report describing the distribution of TNF alpha promoter alleles in the Southeastern United States. The high DRB1*09 and TNF alpha -308A allele frequencies of our population most resemble the frequencies of these alleles in certain West African populations [8].
• This study characterizes the environmental releases of toxic chemicals of the Toxic Chemical Release Inventory (TRI) in the southeastern United States by using the U.S. Environmental Protection Agency (EPA) Geographic Information System (GIS) to map them [9].

Associations of Southeastern United States with chemical compounds

• For each race-gender group, high age-adjusted stroke mortality rates were significantly clustered in the southeastern United States, particularly in the South Atlantic census division, with persistent extreme rates in Georgia and the Carolinas [10].
• Six polybrominated diphenyl ethers (PBDEs), one hexabromobiphenyl [polybrominated biphenyl (PBB)], and one hexachlorobiphenyl [polychlorinated biphenyl (PCB)] were measured in 40 human serum pools collected in the southeastern United States during 1985 through 2002 and in Seattle, Washington, for 1999 through 2002 [11].
• Modeling results showed that, on an annual basis, for the Great Lakes basin as a whole, the southeast U.S. sources made the largest contribution to the toxaphene air concentrations and dry and wet depositions at 72%, 78%, and 88% respectively [12].
• OBJECTIVE: To determine if a polymorphism of the dopamine D3 receptor gene (2 allele), which has been reported previously to be associated with polycystic ovary syndrome (PCOS) in a population of United States Hispanic women, is associated with the disorder in the southeastern United States. DESIGN: Prospective case-control study [13].
• Two diarylbutane derivatives of dihydroguaiaretic acid have been isolated from emergent portions of the southeastern United States freshwater angiosperm Saururus cernuus L [14].

Gene context of Southeastern United States

• Thus, the incidence of bacterial wilt of tobacco in the southeastern United States is partially explained by which avrA allele dominates the local R. solanacearum population [15].
• Juvenile hemochromatosis in the southeastern United States: a report of seven cases in two kinships [16].
• CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States [17].
• HPS cases from the southeastern United States may be exceptional in that they have exhibited both pulmonary and renal manifestations [18].
• A two-stage epidemiologic study conducted between 1986 and 1988 in the southeastern United States investigated the frequency of major depressive disorder and dysthymia in 12-14 year olds [19].

Analytical, diagnostic and therapeutic context of Southeastern United States

• Fifty sera collected from residents of the southeastern United States all had reciprocal ELISA titers less than or equal to 320 [20].

References