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Chemical Compound Review

Calderol     (6R)-6-[(1R,4E,7aR)-4-[(2Z)- 2-[(5R)-5...

Synonyms: Delakmin, Calcifidiol, CHEMBL1040, CHEMBL1222, S1469_Selleck, ...
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Disease relevance of Calcidiol


Psychiatry related information on Calcidiol

  • MEASUREMENTS: Intake of vitamin D and serum levels of 25-hydroxyvitamin D, calculated on the basis of dietary habits and supplement use as reported on a questionnaire, were evaluated at examination 20 (1988 to 1989) [6].
  • MATERIALS AND METHODS: We studied 3100 women (50-63 years old) with bone markers, 25-hydroxyvitamin D, calcium, PTH, diet, and physical activity collected in 1998-2000 [7].
  • However, in an analysis restricted to men with plasma 25-hydroxyvitamin D below the median, we observed a 57% reduction (RR = 0.43, 95% CI = 0.19-0.98) in risk for those with the BB versus the bb genotype; the risk reduction was particularly marked among older men (RR = 0.18, 95% CI = 0.05-0.68) [8].
  • This relationship remained significant after adjustment for testosterone, estradiol, 25-hydroxyvitamin D, and parathyroid hormone levels (r = 0.22, P = 0.01) and after additional adjustment for age, (BM), activity, cigarette and alcohol consumption, and Kellgren/Lawrence score (r = 0.19, P = 0.03) [9].
  • Each subject had a dietary assessment, mental test score, outdoor score, serum 25 hydroxyvitamin D level, and a general biochemical screening at baseline in April 1993 which was repeated in September 1993, April 1994, and September 1994 [10].

High impact information on Calcidiol


Chemical compound and disease context of Calcidiol


Biological context of Calcidiol


Anatomical context of Calcidiol


Associations of Calcidiol with other chemical compounds


Gene context of Calcidiol


Analytical, diagnostic and therapeutic context of Calcidiol


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  2. Treatment of hypoparathyroidism and pseudohypoparathyroidism with metabolites of vitamin D: evidence for impaired conversion of 25-hydroxyvitamin D to 1 alpha,25-dihydroxyvitamin D. Kooh, S.W., Fraser, D., DeLuca, H.F., Holick, M.F., Belsey, R.E., Clark, M.B., Murray, T.M. N. Engl. J. Med. (1975) [Pubmed]
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  13. Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent. Berndt, T., Craig, T.A., Bowe, A.E., Vassiliadis, J., Reczek, D., Finnegan, R., Jan De Beur, S.M., Schiavi, S.C., Kumar, R. J. Clin. Invest. (2003) [Pubmed]
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  20. Correlation between serum osteocalcin and 24,25-dihydroxyvitamin D levels in Paget's disease of bone. Castro-Errecaborde, N., de la Piedra, C., Rapado, A., Alvarez-Arroyo, M.V., Torres, R., Traba, M.L. J. Clin. Endocrinol. Metab. (1991) [Pubmed]
  21. Vitamin D3 and calcium to prevent hip fractures in the elderly women. Chapuy, M.C., Arlot, M.E., Duboeuf, F., Brun, J., Crouzet, B., Arnaud, S., Delmas, P.D., Meunier, P.J. N. Engl. J. Med. (1992) [Pubmed]
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