The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Expert Systems

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Expert Systems

 

Psychiatry related information on Expert Systems

  • The expert system considers different prior probabilities of stage changes depending on the preceding sleep stage, the occurrence of a movement arousal and the position of the epoch within the NREM/REM sleep cycles [6].
 

High impact information on Expert Systems

  • METHODS: A total of 1026 individuals 60 years or older representative of the general population living in the metropolitan area of Paris, France, were interviewed by telephone using the Sleep-EVAL expert system [7].
  • BACKGROUND: The Laboratory Advisory System (LAS) is an expert system interface that works interactively with clinicians to assist them with test selection and result interpretation throughout the laboratory investigation of a patient [8].
  • This pattern, developed in the ARIADNE protein expert system, is used to search for thioredoxin-like tertiary structural motif among proteins for which the only structural information is the primary sequence [9].
  • With the aid of an expert system software (Mass Frontier version 3.0), accurate mass measurements, and multiple stage tandem mass spectrometric (MS(n)) experiments, fragmentation pathways were elucidated for boldenone, methandrostenolone, tetrahydrogestrinone (THG), trenbolone, normethandrolone and mibolerone [10].
  • Finally, we implement semi-automated virus reconstruction (SAVR), an expert system that integrates the most CPU intensive and iterative steps using the scripting language Python [11].
 

Chemical compound and disease context of Expert Systems

 

Biological context of Expert Systems

  • In order to identify the essential structural and physicochemical requirements in terms of common biophoric sites (pharmacophore) and secondary sites for binding and interacting with 5-lipoxygenase, a series of 51 compounds of chalcones has been used for the development of 3D-QSAR models on APEX-3D expert system [14].
  • Heart-rate variability and SIDS. Examination of heart-rate patterns using an expert system generator [15].
  • In addition to the control of FES, such techniques are also applicable to automatic gait analysis and the construction of expert systems for diagnosis of gait pathologies [16].
 

Anatomical context of Expert Systems

  • In this paper we present a rule-based expert system for the automatic delineation and 3D reconstruction of the left coronary artery on standard RAO and LAO angiographic projections [17].
 

Associations of Expert Systems with chemical compounds

  • Taking advantage of the rule-based expert system technology, a program named RUBIDIUM (Rule-Based Identification In 2D NMR Spectrum) was developed to accomplish the automatic 1H NMR resonance assignments of polypeptides [18].
  • The values of the variables were then entered into an expert system (Expert Ease) in order to achieve classification of patients into emboli versus no emboli groups, while using a minimal number of variables [19].
  • Expert systems have been used in Medicine for many years, but they are usually highly sophisticated and not well integrated into day-to-day practice [20].
  • Sherpa: a Macintosh-based expert system for the interpretation of electrospray ionization LC/MS and MS/MS data from protein digests [21].
  • Using the expert system, META, a series of putative metabolites of thalidomide was generated [22].
 

Gene context of Expert Systems

  • Using the results of this analysis, an exploratory expert system was developed for use in ranking relative ER binding affinity potential for large chemical data sets [23].
  • OBJECTIVE: To describe the role of an expert system applied to the control of MRSA at a large medical center (1,600 beds) with high endemic rates [24].
  • Evaluation of atopy through an expert system: description of the database [25].
  • An expert system has been integrated to the data management system of the ARTEMIS programme for hypertensive patients [26].
  • OURCIN is a tool to build expert systems, which was developed by a joint team from INRIA and SEMA [27].
 

Analytical, diagnostic and therapeutic context of Expert Systems

References

  1. Knowledge-based expert systems for toxicity and metabolism prediction: DEREK, StAR and METEOR. Greene, N., Judson, P.N., Langowski, J.J., Marchant, C.A. SAR and QSAR in environmental research. (1999) [Pubmed]
  2. Induction of forward mutations at the thymidine kinase locus of mouse lymphoma cells: evidence for electrophilic and non-electrophilic mechanisms. Henry, B., Grant, S.G., Klopman, G., Rosenkranz, H.S. Mutat. Res. (1998) [Pubmed]
  3. BRAINDEX: an interactive, knowledge-based system supporting brain death diagnosis. Rom, G., Schwarz, G., Grims, R., Rumpl, E., Pfurtscheller, G., Haase, V. Methods of information in medicine. (1990) [Pubmed]
  4. Development of an expert system for bacterial identification: study of a prototype for identifying beta-galactosidase positive enterobacteria. Gavini, F., Lefebvre, B., Hamze, M., Izard, D. J. Appl. Bacteriol. (1990) [Pubmed]
  5. A Grid-based HIV expert system. Sloot, P.M., Boukhanovsky, A.V., Keulen, W., Tirado-Ramos, A., Boucher, C.A. Journal of clinical monitoring and computing. (2005) [Pubmed]
  6. An E-health solution for automatic sleep classification according to Rechtschaffen and Kales: validation study of the Somnolyzer 24 x 7 utilizing the Siesta database. Anderer, P., Gruber, G., Parapatics, S., Woertz, M., Miazhynskaia, T., Klosch, G., Saletu, B., Zeitlhofer, J., Barbanoj, M.J., Danker-Hopfe, H., Himanen, S.L., Kemp, B., Penzel, T., Grozinger, M., Kunz, D., Rappelsberger, P., Schlogl, A., Dorffner, G. Neuropsychobiology (2005) [Pubmed]
  7. Daytime sleepiness and cognitive impairment in the elderly population. Ohayon, M.M., Vecchierini, M.F. Arch. Intern. Med. (2002) [Pubmed]
  8. The influence of an expert system for test ordering and interpretation on laboratory investigations. Smith, B.J., McNeely, M.D. Clin. Chem. (1999) [Pubmed]
  9. Identification of the three-dimensional thioredoxin motif: related structure in the ORF3 protein of the Staphylococcus aureus mer operon. Ellis, L.B., Saurugger, P., Woodward, C. Biochemistry (1992) [Pubmed]
  10. Collision-induced dissociation pathways of anabolic steroids by electrospray ionization tandem mass spectrometry. Guan, F., Soma, L.R., Luo, Y., Uboh, C.E., Peterman, S. J. Am. Soc. Mass Spectrom. (2006) [Pubmed]
  11. Semi-automated icosahedral particle reconstruction at sub-nanometer resolution. Jiang, W., Li, Z., Zhang, Z., Booth, C.R., Baker, M.L., Chiu, W. J. Struct. Biol. (2001) [Pubmed]
  12. The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements. Lindon, J.C., Keun, H.C., Ebbels, T.M., Pearce, J.M., Holmes, E., Nicholson, J.K. Pharmacogenomics (2005) [Pubmed]
  13. The performance characteristics of an expert system for the "on-line" assessment of thalassemia trait and iron deficiency--Micro Hema Screen. Paterakis, G.S., Terzoglou, G., Vasilioy, E. Blood Cells (1989) [Pubmed]
  14. Development of 3D-QSAR models for 5-lipoxygenase antagonists: chalcones. Arockia Babu, M., Shakya, N., Prathipati, P., Kaskhedikar, S.G., Saxena, A.K. Bioorg. Med. Chem. (2002) [Pubmed]
  15. Heart-rate variability and SIDS. Examination of heart-rate patterns using an expert system generator. Välimäki, I.A., Nieminen, T., Antila, K.J., Southall, D.P. Ann. N. Y. Acad. Sci. (1988) [Pubmed]
  16. Automatic detection of gait events: a case study using inductive learning techniques. Kirkwood, C.A., Andrews, B.J., Mowforth, P. Journal of biomedical engineering. (1989) [Pubmed]
  17. An expert system for the labeling and 3D reconstruction of the coronary arteries from two projections. Smets, C., van de Werf, F., Suetens, P., Oosterlinck, A. International journal of cardiac imaging. (1990) [Pubmed]
  18. RUBIDIUM, a program for computer-aided assignment of two-dimensional NMR spectra of polypeptides. Yu, C., Hwang, J.F., Chen, T.B., Soo, V.W. Journal of chemical information and computer sciences. (1992) [Pubmed]
  19. Classification of left ventricular thrombi by their history of systemic embolization using pattern recognition of two-dimensional echocardiograms. Lloret, R.L., Cortada, X., Bradford, J., Metz, M.N., Kinney, E.L. Am. Heart J. (1985) [Pubmed]
  20. Using OMIM (On-line Mendelian Inheritance in Man) as an expert system in medical genetics. Schorderet, D.F. Am. J. Med. Genet. (1991) [Pubmed]
  21. Sherpa: a Macintosh-based expert system for the interpretation of electrospray ionization LC/MS and MS/MS data from protein digests. Taylor, J.A., Walsh, K.A., Johnson, R.S. Rapid Commun. Mass Spectrom. (1996) [Pubmed]
  22. Thalidomide and metabolites: indications of the absence of 'genotoxic' carcinogenic potentials. Zhu, X., Zhang, Y.P., Klopman, G., Rosenkranz, H.S. Mutat. Res. (1999) [Pubmed]
  23. A computationally based identification algorithm for estrogen receptor ligands: part 1. Predicting hERalpha binding affinity. Bradbury, S., Kamenska, V., Schmieder, P., Ankley, G., Mekenyan, O. Toxicol. Sci. (2000) [Pubmed]
  24. Automatic alerts for methicillin-resistant Staphylococcus aureus surveillance and control: role of a hospital information system. Pittet, D., Safran, E., Harbarth, S., Borst, F., Copin, P., Rohner, P., Scherrer, J.R., Auckenthaler, R. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America. (1996) [Pubmed]
  25. Evaluation of atopy through an expert system: description of the database. Ray, P., Vervloet, D., Charpin, D., Gautier, V., Proudhon, H., Redier, H., Godard, P. Clin. Exp. Allergy (1995) [Pubmed]
  26. Integrating management and expertise in a computerised system for hypertensive patients. Devriès, C., Degoulet, P., Jeunemaitre, X., Sauquet, D., Morice, V., Chatellier, G., Aime, F., Ménard, J. Nephrol. Dial. Transplant. (1987) [Pubmed]
  27. OURCIN: a tool to build expert systems. Quinqueton, J. Biochimie (1985) [Pubmed]
  28. Prototype expert system for infusion pump maintenance. Mataban, B.A. Biomedical instrumentation & technology / Association for the Advancement of Medical Instrumentation. (1994) [Pubmed]
 
WikiGenes - Universities