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MeSH Review

Collagen Diseases

 
 
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Disease relevance of Collagen Diseases

 

High impact information on Collagen Diseases

  • Clinical and serologic assessment excluded other causes of hepatic dysfunction, such as viral hepatitis, administration of other drugs, or worsening of the collagen disease and the patient was improved 2 wk after azathioprine was discontinued [6].
  • On the basis of these results and by analogy to certain collagen diseases such as systemic lupus erythematosus, we speculate that BS cells are deficient in the detoxification of active oxygen species [7].
  • Folding abnormalities of the triple helix have been demonstrated in collagen diseases such as osteogenesis imperfecta in which the mutation leads to the substitution of a single Gly in the (Gly-X-Y)n sequence pattern by a larger residue [8].
  • Plasma levels of alpha 2-plasmin inhibitor (alpha 2PI) and alpha 2-plasmin inhibitor-plasmin complex (alpha 2 PIPC) were measured by sandwich enzyme-linked immunosorbent assay, using a recently developed monoclonal anti-alpha 2PI antibody, in patients with collagen diseases [9].
  • In a genome-wide screening of the MRL background genes mediating susceptibility to collagen diseases using N2 progeny mice MRL/lpr x (MRL/lpr x C3H/lpr)F1, we previously found that each collagen disease is controlled by a different set of genes [10].
 

Chemical compound and disease context of Collagen Diseases

 

Biological context of Collagen Diseases

 

Anatomical context of Collagen Diseases

 

Gene context of Collagen Diseases

 

Analytical, diagnostic and therapeutic context of Collagen Diseases

References

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  22. Tc-99m DTPA renography in patients with collagen disease. Tezuka, M., Murata, Y., Ishida, R., Sawada, Y., Shibuya, H. Clinical nuclear medicine. (2001) [Pubmed]
  23. Haplotype frequencies of the collagen type-I genes in the Italian population. Mottes, M., Cugola, L., Pignatti, P.F. Hum. Genet. (1989) [Pubmed]
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