The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Collagen Diseases

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Collagen Diseases


High impact information on Collagen Diseases

  • Clinical and serologic assessment excluded other causes of hepatic dysfunction, such as viral hepatitis, administration of other drugs, or worsening of the collagen disease and the patient was improved 2 wk after azathioprine was discontinued [6].
  • On the basis of these results and by analogy to certain collagen diseases such as systemic lupus erythematosus, we speculate that BS cells are deficient in the detoxification of active oxygen species [7].
  • Folding abnormalities of the triple helix have been demonstrated in collagen diseases such as osteogenesis imperfecta in which the mutation leads to the substitution of a single Gly in the (Gly-X-Y)n sequence pattern by a larger residue [8].
  • Plasma levels of alpha 2-plasmin inhibitor (alpha 2PI) and alpha 2-plasmin inhibitor-plasmin complex (alpha 2 PIPC) were measured by sandwich enzyme-linked immunosorbent assay, using a recently developed monoclonal anti-alpha 2PI antibody, in patients with collagen diseases [9].
  • In a genome-wide screening of the MRL background genes mediating susceptibility to collagen diseases using N2 progeny mice MRL/lpr x (MRL/lpr x C3H/lpr)F1, we previously found that each collagen disease is controlled by a different set of genes [10].

Chemical compound and disease context of Collagen Diseases


Biological context of Collagen Diseases


Anatomical context of Collagen Diseases


Gene context of Collagen Diseases


Analytical, diagnostic and therapeutic context of Collagen Diseases


  1. Cardiac involvement in collagen diseases. Toumanidis, S.T., Papamichael, C.M., Antoniades, L.G., Pantelia, M.I., Saridakis, N.S., Mavrikakis, M.E., Sideris, D.A., Moulopoulos, S.D. Eur. Heart J. (1995) [Pubmed]
  2. Sildenafil for primary and secondary pulmonary hypertension. Watanabe, H., Ohashi, K., Takeuchi, K., Yamashita, K., Yokoyama, T., Tran, Q.K., Satoh, H., Terada, H., Ohashi, H., Hayashi, H. Clin. Pharmacol. Ther. (2002) [Pubmed]
  3. Recurrent opticomyelitis associated with anti-DNA antibody. Kira, J., Goto, I. J. Neurol. Neurosurg. Psychiatr. (1994) [Pubmed]
  4. The clinical effect of dietary supplementation with omega-3 fish oils and/or copper in systemic lupus erythematosus. Duffy, E.M., Meenagh, G.K., McMillan, S.A., Strain, J.J., Hannigan, B.M., Bell, A.L. J. Rheumatol. (2004) [Pubmed]
  5. Removal of denatured proteins with artificial reticulo-endothelial system (ARES). Maeda, K., Tsuruta, Y., Shinzato, T., Yamada, K. The International journal of artificial organs. (1986) [Pubmed]
  6. Azathioprine and the liver. Evidence favoring idiosyncratic, mixed cholestatic-hepatocellular injury in humans. DePinho, R.A., Goldberg, C.S., Lefkowitch, J.H. Gastroenterology (1984) [Pubmed]
  7. Clastogenic activity from Bloom syndrome fibroblast cultures. Emerit, I., Cerutti, P. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
  8. Transformation of the mechanism of triple-helix peptide folding in the absence of a C-terminal nucleation domain and its implications for mutations in collagen disorders. Buevich, A.V., Silva, T., Brodsky, B., Baum, J. J. Biol. Chem. (2004) [Pubmed]
  9. Elevated plasma levels of alpha 2-plasmin inhibitor-plasmin complex in patients with rheumatic diseases. Possible role of fibrinolytic mechanism in vasculitis. Kawakami, M., Kawagoe, M., Harigai, M., Hara, M., Hirose, T., Hirose, W., Norioka, K., Suzuki, K., Kitani, A., Nakamura, H. Arthritis Rheum. (1989) [Pubmed]
  10. Genetic dissection of vasculitis in MRL/lpr lupus mice: a novel susceptibility locus involving the CD72c allele. Qu, W.M., Miyazaki, T., Terada, M., Lu, L.M., Nishihara, M., Yamada, A., Mori, S., Nakamura, Y., Ogasawara, H., Yazawa, C., Nakatsuru, S., Nose, M. Eur. J. Immunol. (2000) [Pubmed]
  11. Molecular defects in the Ehlers-Danlos syndrome. Pinnell, S.R. J. Invest. Dermatol. (1982) [Pubmed]
  12. Effects of prostaglandin E1 on collagen diseases with high levels of circulating immune complexes. Yoshikawa, T., Suzuki, H., Kato, H., Yano, S. J. Rheumatol. (1990) [Pubmed]
  13. Prevention of diabetes, hepatic injury, and colon cancer with dehydroepiandrosterone. Aoki, K., Nakajima, A., Mukasa, K., Osawa, E., Mori, Y., Sekihara, H. J. Steroid Biochem. Mol. Biol. (2003) [Pubmed]
  14. Immunological changes in hydroxyurea-induced collagen disease. Layton, A.M., Cotterill, J.A. Br. J. Dermatol. (1994) [Pubmed]
  15. Genome analysis of collagen disease in MRL/lpr mice: polygenic inheritance resulting in the complex pathological manifestations. Nose, M., Terada, M., Nishihara, M., Kamogawa, J., Miyazaki, T., Qu, W., Mori, S., Nakatsuru, S. International journal of cardiology. (2000) [Pubmed]
  16. Plasma coagulation and fibrinolysis parameters in patients with collagen diseases, and analysis of the multimeric structure of von Willebrand factor (vWF). Kagawa, H., Okubo, S., Yasunaga, K. Int. J. Hematol. (1991) [Pubmed]
  17. In vitro spontaneous and UVB-induced lymphocyte apoptosis are not specific to SLE. Abe, M., Ishikawa, O., Miyachi, Y., Kanai, Y. Photodermatology, photoimmunology & photomedicine. (1997) [Pubmed]
  18. Neutrophil function in systemic lupus erythematosus and other collagen diseases. Al-Hadithy, H., Isenberg, D.A., Addison, I.E., Goldstone, A.H., Snaith, M.L. Ann. Rheum. Dis. (1982) [Pubmed]
  19. A paradoxical effect of hydralazine on prolyl and lysyl hydroxylase activities in cultured human skin fibroblasts. Murad, S., Tajima, S., Pinnell, S.R. Arch. Biochem. Biophys. (1985) [Pubmed]
  20. Bilateral necrotizing scleritis. Hatsuda, T.A., Tanaka, J. Am. J. Ophthalmol. (1978) [Pubmed]
  21. Diagnostic value of determinations of lysosomal hydrolases in CSF of patients with neurological diseases. Hultberg, B., Olsson, J.E. Acta neurologica Scandinavica. (1978) [Pubmed]
  22. Tc-99m DTPA renography in patients with collagen disease. Tezuka, M., Murata, Y., Ishida, R., Sawada, Y., Shibuya, H. Clinical nuclear medicine. (2001) [Pubmed]
  23. Haplotype frequencies of the collagen type-I genes in the Italian population. Mottes, M., Cugola, L., Pignatti, P.F. Hum. Genet. (1989) [Pubmed]
  24. Serum concentrations of vascular endothelial growth factor in collagen diseases. Kikuchi, K., Kubo, M., Kadono, T., Yazawa, N., IHN, H., Tamaki, K. Br. J. Dermatol. (1998) [Pubmed]
  25. Thin glomerular basement membrane disease. Frascá, G.M., Onetti-Muda, A., Renieri, A. J. Nephrol. (2000) [Pubmed]
  26. Serum concentrations of basic fibroblast growth factor in collagen diseases. Kadono, T., Kikuchi, K., Kubo, M., Fujimoto, M., Tamaki, K. J. Am. Acad. Dermatol. (1996) [Pubmed]
  27. Plasma protein S in disseminated intravascular coagulation, liver disease, collagen disease, diabetes mellitus, and under oral anticoagulant therapy. Takahashi, H., Tatewaki, W., Wada, K., Shibata, A. Clin. Chim. Acta (1989) [Pubmed]
  28. Osteonecrosis of the femoral head in immunosuppressed patients: hip salvaging with implantation of a vascularised fibular graft. Malizos, K.N., Soucacos, P.N., Beris, A.E., Korobilias, A.B., Xenakis, T.A. Microsurgery. (1994) [Pubmed]
  29. Investigation of EB virus and cytomegalovirus in rapidly progressive interstitial pneumonitis in polymyositis/dermatomyositis by in situ hybridization and polymerase chain reaction. Hashimoto, Y., Nawata, Y., Kurasawa, K., Takabayashi, K., Oda, K., Mikata, A., Iwamoto, I. Clin. Immunol. Immunopathol. (1995) [Pubmed]
WikiGenes - Universities