Chemical Compound Review:
SureCN563335 7-phenylmethoxyphenoxazin-3- one
Synonyms:
AG-H-53965, B1532_SIGMA, AC1L3GBQ, CTK8D9518, STK299141, ...
- Reassessment of cytochrome P450 2B2: catalytic specificity and identification of four active site residues. Strobel, S.M., Halpert, J.R. Biochemistry (1997)
- Modulation by iron of hepatic microsomal and nuclear cytochrome P450, and cytosolic glutathione S-transferase and peroxidase in C57BL/10ScSn mice induced with polychlorinated biphenyls (Aroclor 1254). Madra, S., Mann, F., Francis, J.E., Manson, M.M., Smith, A.G. Toxicol. Appl. Pharmacol. (1996)
- Lack of evidence for induction of CYP2B1, CYP3A23, and CYP1A2 gene expression by Panax ginseng and Panax quinquefolius extracts in adult rats and primary cultures of rat hepatocytes. Yu, C.T., Chen, J., Teng, X.W., Tong, V., Chang, T.K. Drug Metab. Dispos. (2005)
- Role of cytochrome P-450 from the human CYP3A gene family in the potentiation of morpholino doxorubicin by human liver microsomes. Lewis, A.D., Lau, D.H., Durán, G.E., Wolf, C.R., Sikic, B.I. Cancer Res. (1992)
- Catalytic selectivity and mechanism-based inactivation of stably expressed and hepatic cytochromes P450 2B4 and 2B5: implications of the cytochrome P450 2B5 polymorphism. Grimm, S.W., Dyroff, M.C., Philpot, R.M., Halpert, J.R. Mol. Pharmacol. (1994)
- Reconstituted epidermis: a novel model for the study of drug metabolism in human epidermis. Pham, M.A., Magdalou, J., Siest, G., Lenoir, M.C., Bernard, B.A., Jamoulle, J.C., Shroot, B. J. Invest. Dermatol. (1990)
- Biodistribution of, antimutagenic efficacies in Salmonella typhimurium of, and inhibition of P450 activities by ellagic acid and one analogue. Castonguay, A., Boukharta, M., Teel, R. Chem. Res. Toxicol. (1998)
- Human adult hepatocytes in primary monolayer culture. Maintenance of mixed function oxidase and conjugation pathways of drug metabolism. Grant, M.H., Burke, M.D., Hawksworth, G.M., Duthie, S.J., Engeset, J., Petrie, J.C. Biochem. Pharmacol. (1987)
- Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent. Wink, D.A., Osawa, Y., Darbyshire, J.F., Jones, C.R., Eshenaur, S.C., Nims, R.W. Arch. Biochem. Biophys. (1993)
- Effects of feeding Artemisia filifolia and Helenium flexuosum on rabbit cytochrome P450 isozymes. Eissa, F.Z., Qualls, C.W., Burrows, G.E., Lish, J.W. Veterinary and human toxicology. (1996)
- The effects of cigarette smoke compared to 3-methylcholanthrene and phenobarbitone on alkoxyresorufin metabolism by lung and liver microsomes from rats. Godden, P.M., Kass, G., Mayer, R.T., Burke, M.D. Biochem. Pharmacol. (1987)
- Effect of interleukin 6 on phenobarbital induction of cytochrome P-450IIB in cultured rat hepatocytes. Williams, J.F., Bement, W.J., Sinclair, J.F., Sinclair, P.R. Biochem. Biophys. Res. Commun. (1991)
- P450 enzyme expression patterns in the NCI human tumor cell line panel. Yu, L.J., Matias, J., Scudiero, D.A., Hite, K.M., Monks, A., Sausville, E.A., Waxman, D.J. Drug Metab. Dispos. (2001)
- Drug metabolizing enzymes in the rat pituitary gland. Ghersi-Egea, J.F., Leininger-Muller, B., Minn, A., Siest, G. Prog. Brain Res. (1992)
- Isolation and characterization of metabolically competent pulmonary epithelial cells from pig lung tissue. Blickwede, M., Borlak, J. Xenobiotica (2005)
- Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes. Yun, C.H., Jeong, H.G., Jhoun, J.W., Guengerich, F.P. Carcinogenesis (1995)
- Human CYP2B6: expression, inducibility and catalytic activities. Gervot, L., Rochat, B., Gautier, J.C., Bohnenstengel, F., Kroemer, H., de Berardinis, V., Martin, H., Beaune, P., de Waziers, I. Pharmacogenetics (1999)
- Further characterization of the expression in liver and catalytic activity of CYP2B6. Ekins, S., Vandenbranden, M., Ring, B.J., Gillespie, J.S., Yang, T.J., Gelboin, H.V., Wrighton, S.A. J. Pharmacol. Exp. Ther. (1998)
- Induction of liver microsomal cytochrome P450 in cynomolgus monkeys. Bullock, P., Pearce, R., Draper, A., Podval, J., Bracken, W., Veltman, J., Thomas, P., Parkinson, A. Drug Metab. Dispos. (1995)
- Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates. Stresser, D.M., Blanchard, A.P., Turner, S.D., Erve, J.C., Dandeneau, A.A., Miller, V.P., Crespi, C.L. Drug Metab. Dispos. (2000)
- Inhibition and inactivation of human cytochrome P450 isoforms by phenethyl isothiocyanate. Nakajima, M., Yoshida, R., Shimada, N., Yamazaki, H., Yokoi, T. Drug Metab. Dispos. (2001)
- Hepatic microsomal cytochrome p450s and chlorinated hydrocarbons in largha and ribbon seals from Hokkaido, Japan: differential response of seal species to Ah receptor agonist exposure. Chiba, I., Sakakibara, A., Iwata, T.H., Ishizuka, M., Tanabe, S., Akahori, F., Kazusaka, A., Fujita, S. Environ. Toxicol. Chem. (2002)
- Utility of microtiter plate assays for human cytochrome P450 inhibition studies in drug discovery: application of simple method for detecting quasi-irreversible and irreversible inhibitors. Naritomi, Y., Teramura, Y., Terashita, S., Kagayama, A. Drug Metab. Pharmacokinet. (2004)
- Changes in cytochrome P450 enzymes by 1,1-dichloroethylene in rat liver and kidney. Hanioka, N., Jinno, H., Nishimura, T., Ando, M. Arch. Toxicol. (1997)
- A comparison of basal and induced hepatic microsomal cytochrome P450 monooxygenase activities in the cynomolgus monkey (Macaca fascicularis) and man. Weaver, R.J., Dickins, M., Burke, M.D. Xenobiotica (1999)
- Assessment of regional cytochrome P450 activities in rat liver slices using resorufin substrates and fluorescence confocal laser cytometry. Heinonen, J.T., Sidhu, J.S., Reilly, M.T., Farin, F.M., Omiecinski, C.J., Eaton, D.L., Kavanagh, T.J. Environ. Health Perspect. (1996)