Disease relevance of polyglyconate

• Monofilament polyglyconate suture does not reduce the incidence of fascial disruption and incisional hernia after laparotomy in patients with suspected impaired wound healing but the incidence of wound infection may be reduced compared with that of multifilament polyglycolic acid suture [1].
• Wound infection demanding surgical intervention was found in 7 per cent of patients with polyglyconate sutures and in 16 per cent of those with polyglycolic acid sutures (P = 0.04) [1].
• INTERVENTIONS: A custom polyglyconate mesh (Vicryl) containing 125I seeds was applied to pulmonary resection margins following wedge resection of peripheral lung cancers [2].
• Eleven patients (4 nylon and 7 polyglyconate) developed a ventral hernia [3].
• The use of polyglyconate in surgery of congenital heart defects: comparison with polypropylene [4].

High impact information on polyglyconate

• Randomized comparison of polyglycolic acid and polyglyconate sutures for abdominal fascial closure after laparotomy in patients with suspected impaired wound healing [5].
• The aim of the study was to investigate the mechanical properties of SR-PLLA sutures in comparison with polyglyconate (Maxon) and polydioxanone (PDS) sutures in vitro [6].
• Comparison of strength properties of poly-L/D-lactide (PLDLA) 96/4 and polyglyconate (Maxon) sutures: in vitro, in the subcutis, and in the achilles tendon of rabbits [7].
• Results of this study lead to the conclusion that a running polyglyconate suture is the better choice for closure of the abdominal-wall fascia following midline laparotomy [8].
• Despite its smaller diameter, the polyglyconate suture also retains a higher tensile strength after surgery than does the quicker-degrading polyglactin 910 suture [8].

Chemical compound and disease context of polyglyconate

• There were no differences in the rate of dehiscence among the groups, but there were significantly more hernias in the polyglyconate group (19/164, 12%) compared with the two in which polyglactin 910 was used (16/327, 5%) [9].

Anatomical context of polyglyconate

• Bioabsorbable polyglyconate interference screw fixation in anterior cruciate ligament reconstruction: a prospective computed tomography-controlled study [10].
• Polyglyconate monofilament sutures with similar diameter (Maxon(R) 4-0, Cyanamid of Great Britain Ltd., Gosport, UK) were implanted in the contralateral gastrocnemius tendon [11].
• Microvascular repair of 34 rat femoral arteries averaging 0.63 mm in diameter using 8-0 polyglyconate suture on an atraumatic needle gave an immediate patency rate of 100% and a late patency rate of 94.1% after 1 to 24 weeks [12].
• Thirty pigs were randomised to bile duct division and anastomosis with either polyglyconate (Maxon), polyglactin 910 (Vicryl) or polypropylene (Prolene) [13].

Associations of polyglyconate with other chemical compounds

• CONCLUSIONS/CLINICAL RELEVANCE: Sterilization with either ethylene oxide or gas plasma of pre-tied, polyglyconate, or polydioxanone ligature loops significantly increases the in vitro likelihood of a modified Roeder knot untying [14].
• The following suture materials have been evaluated for their suitability for use in flexor tendon repairs: 4/0 gauge monofilament and multifilament stainless steel, mono-filament nylon, monofilament polypropylene, monofilament polybutestor, braided polyester, braided polyglycolic acid and a monofilament polyglyconate [15].

Gene context of polyglyconate

• Primary mass closure of midline incisions with a continuous polyglyconate monofilament absorbable suture [16].
• This study shows that the polyglyconate screw is an effective alternative to metal in endoscopic reconstruction of the ACL [17].

Analytical, diagnostic and therapeutic context of polyglyconate

• Sutures of chromic catgut and two monofilament absorbable synthetic suture materials (polydioxanone and polyglyconate) were used to close a synovial incision in the knees of sheep [18].
• A transanal endorectal mucosal dissection and a coloanal anastomosis were done, using an absorbable monofilament 5/0 polyglyconate suture [19].
• Polyglyconate fixation successfully stabilizes zygomatic osteotomies in a nonhuman primate [20].
• Ligatures tied with polyglyconate and size 1 suture had the highest mean peak force to failure [21].
• The custom-designed cannula provided good access to the operative site and no complications were encountered with use of polyglyconate suture material for nephrosplenic space closure [22].

References