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Chemical Compound Review

Bromodeoxycytidine     4-amino-5-bromo-1-[(2R,5R)-4- hydroxy-5...

Synonyms: Brcdr, BCDR, SureCN198512, LS-59064, NSC 61765, ...
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Disease relevance of Bromodeoxycytidine


High impact information on Bromodeoxycytidine


Biological context of Bromodeoxycytidine


Anatomical context of Bromodeoxycytidine


Associations of Bromodeoxycytidine with other chemical compounds


Analytical, diagnostic and therapeutic context of Bromodeoxycytidine


  1. Incorporation of 5-bromodeoxycytidine in the adenovirus 2 replication origin interferes with nuclear factor 1 binding. de Vries, E., Bloemers, S.M., van der Vliet, P.C. Nucleic Acids Res. (1987) [Pubmed]
  2. Enzymatic basis for the selective inhibition of varicella-zoster virus by 5-halogenated analogues of deoxycytidine. Dobersen, M.J., Jerkofsky, M., Greer, S. J. Virol. (1976) [Pubmed]
  3. Radiosensitization of rat glioma with bromodeoxycytidine and adenovirus expressing herpes simplex virus-thymidine kinase delivered by slow, rate-controlled positive pressure infusion. Brust, D., Feden, J., Farnsworth, J., Amir, C., Broaddus, W.C., Valerie, K. Cancer Gene Ther. (2000) [Pubmed]
  4. Inhibition of the replication of human cytomegalovirus by bromodeoxycytidine in the absence of detectable increases in bromodeoxycytidine kinase activity. Jerkofsky, M., Dobersen, M.J., Greer, S. Intervirology (1980) [Pubmed]
  5. Bromination of deoxycytidine by eosinophil peroxidase: a mechanism for mutagenesis by oxidative damage of nucleotide precursors. Henderson, J.P., Byun, J., Williams, M.V., McCormick, M.L., Parks, W.C., Ridnour, L.A., Heinecke, J.W. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  6. Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation. Henderson, J.P., Byun, J., Williams, M.V., Mueller, D.M., McCormick, M.L., Heinecke, J.W. J. Biol. Chem. (2001) [Pubmed]
  7. Exogenous stem cell factor (SCF) compensates for altered endogenous SCF expression in 2,5-hexanedione-induced testicular atrophy in rats. Allard, E.K., Blanchard, K.T., Boekelheide, K. Biol. Reprod. (1996) [Pubmed]
  8. Thymidine kinase deletion mutants of herpes simplex virus type 1. Sanders, P.G., Wilkie, N.M., Davison, A.J. J. Gen. Virol. (1982) [Pubmed]
  9. 5-Bromodeoxycytidine in the study of sister chromatid exchanges in human lymphocytes. Zakharov, A.F., Bairamjan, T.L. Hum. Genet. (1980) [Pubmed]
  10. Is vasospasm related to proliferative arteriopathy? Pluta, R.M., Zauner, A., Morgan, J.K., Muraszko, K.M., Oldfield, E.H. J. Neurosurg. (1992) [Pubmed]
  11. Cell cycle kinetic measurements in an irradiated rat rhabdomyosarcoma using a monoclonal antibody to bromodeoxyuridine. Nüsse, M., Afzal, S.M., Carr, B., Kavanau, K. Cytometry. (1985) [Pubmed]
  12. Cell proliferation in the bone marrow, thymus and spleen of mice studied by continuous, in vivo bromodeoxycytidine labelling and flow cytometric analysis. Crippen, T.L., Jones, I.M. Cell and tissue kinetics. (1989) [Pubmed]
  13. Mechanism of degradation of 2'-deoxycytidine by formamide: implications for chemical DNA sequencing procedures. Saladino, R., Crestini, C., Mincione, E., Costanzo, G., Di Mauro, E., Negri, R. Bioorg. Med. Chem. (1997) [Pubmed]
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