Chemical Compound Review:
CHEMBL399906 seleninomethane
Synonyms:
AG-E-90634, LS-90052, CTK1A6305, AR-1J4068, AR-1J4069, ...
- Diverse effects of methylseleninic acid on the transcriptional program of human prostate cancer cells. Zhao, H., Whitfield, M.L., Xu, T., Botstein, D., Brooks, J.D. Mol. Biol. Cell (2004)
- Intracellular glutathione is a cofactor in methylseleninic acid-induced apoptotic cell death of human hepatoma HEPG(2) cells. Shen, H.M., Ding, W.X., Ong, C.N. Free Radic. Biol. Med. (2002)
- Cell cycle arrest biomarkers in human lung cancer cells after treatment with selenium in culture. Swede, H., Dong, Y., Reid, M., Marshall, J., Ip, C. Cancer Epidemiol. Biomarkers Prev. (2003)
- Synergy between selenium and vitamin E in apoptosis induction is associated with activation of distinctive initiator caspases in human prostate cancer cells. Zu, K., Ip, C. Cancer Res. (2003)
- Mechanisms of cell cycle arrest by methylseleninic acid. Zhu, Z., Jiang, W., Ganther, H.E., Thompson, H.J. Cancer Res. (2002)
- Antimitogenic and proapoptotic activities of methylseleninic acid in vascular endothelial cells and associated effects on PI3K-AKT, ERK, JNK and p38 MAPK signaling. Wang, Z., Jiang, C., Ganther, H., Lü, J. Cancer Res. (2001)
- Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells. Jiang, C., Wang, Z., Ganther, H., Lu, J. Cancer Res. (2001)
- Augmented suppression of androgen receptor signaling by a combination of alpha-tocopheryl succinate and methylseleninic acid. Zhang, H., Wu, Y., Malewicz, B., Lu, J., Li, S., Marshall, J., Ip, C., Dong, Y. Cancer (2006)
- Inhibition of androgen receptor signaling by selenite and methylseleninic acid in prostate cancer cells: two distinct mechanisms of action. Husbeck, B., Bhattacharyya, R.S., Feldman, D., Knox, S.J. Mol. Cancer Ther. (2006)
- Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription. Cho, S.D., Jiang, C., Malewicz, B., Dong, Y., Young, C.Y., Kang, K.S., Lee, Y.S., Ip, C., Lü, J. Mol. Cancer Ther. (2004)
- Distribution and reuse of (76)Se-selenosugar in selenium-deficient rats. Suzuki, K.T., Somekawa, L., Suzuki, N. Toxicol. Appl. Pharmacol. (2006)
- Evidence of a field effect associated with mammary cancer chemoprevention by methylseleninic acid. Dong, Y., Ip, C., Ganther, H. Anticancer Res. (2002)
- In vitro and in vivo studies of methylseleninic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention. Ip, C., Thompson, H.J., Zhu, Z., Ganther, H.E. Cancer Res. (2000)
- Selenomethionine induced transcriptional programs in human prostate cancer cells. Zhao, H., Brooks, J.D. J. Urol. (2007)
- Allium chemistry: synthesis, natural occurrence, biological activity, and chemistry of Se-alk(en)ylselenocysteines and their gamma-glutamyl derivatives and oxidation products. Block, E., Birringer, M., Jiang, W., Nakahodo, T., Thompson, H.J., Toscano, P.J., Uzar, H., Zhang, X., Zhu, Z. J. Agric. Food Chem. (2001)
- Monomethyl selenium--specific inhibition of MMP-2 and VEGF expression: implications for angiogenic switch regulation. Jiang, C., Ganther, H., Lu, J. Mol. Carcinog. (2000)
- Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate-specific antigen (PSA). Lee, S.O., Yeon Chun, J., Nadiminty, N., Trump, D.L., Ip, C., Dong, Y., Gao, A.C. Prostate (2006)
- Androgen receptor signaling intensity is a key factor in determining the sensitivity of prostate cancer cells to selenium inhibition of growth and cancer-specific biomarkers. Dong, Y., Zhang, H., Gao, A.C., Marshall, J.R., Ip, C. Mol. Cancer Ther. (2005)