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Chemical Compound Review

CHEMBL150098     2,3,4,5-tetrabromo-6-(3,5- dibromo-2...

Synonyms: CHEBI:348085, NSC-364753, AC1L7PIZ, NSC364753, 80246-27-1, ...
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  • ObjectivesOur objectives in this study were to expand a previously reported U.S. market basket survey using a larger sample size and to estimate levels of PBDE intake from food for the U.S. general population by sex and age.MethodsWe measured concentrations of 13 polybrominated diphenyl ether (PBDE) congeners in food in 62 food samples [26].


  1. Different levels of polybrominated diphenyl ethers (PBDEs) and chlorinated compounds in breast milk from two U.K. Regions. Kalantzi, O.I., Martin, F.L., Thomas, G.O., Alcock, R.E., Tang, H.R., Drury, S.C., Carmichael, P.L., Nicholson, J.K., Jones, K.C. Environ. Health Perspect. (2004) [Pubmed]
  2. Is bone mineral composition disrupted by organochlorines in east Greenland polar bears (Ursus maritimus)? Sonne, C., Dietz, R., Born, E.W., Riget, F.F., Kirkegaard, M., Hyldstrup, L., Letcher, R.J., Muir, D.C. Environ. Health Perspect. (2004) [Pubmed]
  3. Are organohalogen contaminants a cofactor in the development of renal lesions in east Greenland polar bears (Ursus maritimus)? Sonne, C., Dietz, R., Leifsson, P.S., Born, E.W., Kirkegaard, M., Letcher, R.J., Muir, D.C., Riget, F.E., Hyldstrup, L. Environ. Toxicol. Chem. (2006) [Pubmed]
  4. Synthesis, activity, and molecular modeling studies of novel human aldose reductase inhibitors based on a marine natural product. de la Fuente, J.A., Manzanaro, S., Martín, M.J., de Quesada, T.G., Reymundo, I., Luengo, S.M., Gago, F. J. Med. Chem. (2003) [Pubmed]
  5. Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United States. Sjödin, A., Jones, R.S., Focant, J.F., Lapeza, C., Wang, R.Y., McGahee, E.E., Zhang, Y., Turner, W.E., Slazyk, B., Needham, L.L., Patterson, D.G. Environ. Health Perspect. (2004) [Pubmed]
  6. Polybrominated diphenyl ethers (PBDEs) in U.S. mothers' milk. Schecter, A., Pavuk, M., Päpke, O., Ryan, J.J., Birnbaum, L., Rosen, R. Environ. Health Perspect. (2003) [Pubmed]
  7. Partitioning and bioaccumulation of PBDEs and PCBs in Lake Michigan. Streets, S.S., Henderson, S.A., Stoner, A.D., Carlson, D.L., Simcik, M.F., Swackhamer, D.L. Environ. Sci. Technol. (2006) [Pubmed]
  8. Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. Staskal, D.F., Hakk, H., Bauer, D., Diliberto, J.J., Birnbaum, L.S. Toxicol. Sci. (2006) [Pubmed]
  9. Quantitative structure-activity relationship models for prediction of the toxicity of polybrominated diphenyl ether congeners. Wang, Y., Liu, H., Zhao, C., Liu, H., Cai, Z., Jiang, G. Environ. Sci. Technol. (2005) [Pubmed]
  10. Levels of polybrominated diphenyl ether (PBDE) flame retardants in animals representing different trophic levels of the North Sea food Web. Boon, J.P., Lewis, W.E., Tjoen-A-Choy, M.R., Allchin, C.R., Law, R.J., De Boer, J., Ten Hallers-Tjabbes, C.C., Zegers, B.N. Environ. Sci. Technol. (2002) [Pubmed]
  11. Is house dust the missing exposure pathway for PBDEs? An analysis of the urban fate and human exposure to PBDEs. Jones-Otazo, H.A., Clarke, J.P., Diamond, M.L., Archbold, J.A., Ferguson, G., Harner, T., Richardson, G.M., Ryan, J.J., Wilford, B. Environ. Sci. Technol. (2005) [Pubmed]
  12. Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships. Kodavanti, P.R., Ward, T.R., Ludewig, G., Robertson, L.W., Birnbaum, L.S. Toxicol. Sci. (2005) [Pubmed]
  13. Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption. Zhou, T., Taylor, M.M., DeVito, M.J., Crofton, K.M. Toxicol. Sci. (2002) [Pubmed]
  14. Identification of hydroxylated polybrominated diphenyl ether metabolites in blood plasma from polybrominated diphenyl ether exposed rats. Malmberg, T., Athanasiadou, M., Marsh, G., Brandt, I., Bergman, A. Environ. Sci. Technol. (2005) [Pubmed]
  15. Hapten syntheses and antibody generation for the development of a polybrominated flame retardant ELISA. Shelver, W.L., Keum, Y.S., Kim, H.J., Rutherford, D., Hakk, H.H., Bergman, A., Li, Q.X. J. Agric. Food Chem. (2005) [Pubmed]
  16. Increased blood interleukin-10 mRNA levels in diseased free-ranging harbor porpoises (Phocoena phocoena). Beineke, A., Siebert, U., M??ller, G., Baumg??rtner, W. Vet. Immunol. Immunopathol. (2007) [Pubmed]
  17. Polybrominated diphenyl ether (PBDE) levels in livers of U.S. human fetuses and newborns. Schecter, A., Johnson-Welch, S., Tung, K.C., Harris, T.R., P??pke, O., Rosen, R. J. Toxicol. Environ. Health Part A (2007) [Pubmed]
  18. Some polybrominated diphenyl ether (PBDE) flame retardants with wide environmental distribution inhibit TCDD-induced EROD activity in primary cultured carp (Cyprinus carpio) hepatocytes. Kuiper, R.V., Bergman, A., Vos, J.G., van den Berg, M. Aquat. Toxicol. (2004) [Pubmed]
  19. Polybrominated diphenyl ether (PBDE)-induced alterations in vitamin A and thyroid hormone concentrations in the rat during lactation and early postnatal development. Ellis-Hutchings, R.G., Cherr, G.N., Hanna, L.A., Keen, C.L. Toxicol. Appl. Pharmacol. (2006) [Pubmed]
  20. Environmental contaminants in arctic foxes (Alopex lagopus) in Svalbard: Relationships with feeding ecology and body condition. Fuglei, E., Bustnes, J.O., Hop, H., Mørk, T., Björnfoth, H., van Bavel, B. Environ. Pollut. (2007) [Pubmed]
  21. Contaminant exposure and reproductive success of ospreys (Pandion haliaetus) nesting in Chesapeake Bay regions of concern. Rattner, B.A., McGowan, P.C., Golden, N.H., Hatfield, J.S., Toschik, P.C., Lukei, R.F., Hale, R.C., Schmitz-Afonso, I., Rice, C.P. Arch. Environ. Contam. Toxicol. (2004) [Pubmed]
  22. Determination of HBCD, PBDEs and MeO-BDEs in California sea lions (Zalophus californianus) stranded between 1993 and 2003. Stapleton, H.M., Dodder, N.G., Kucklick, J.R., Reddy, C.M., Schantz, M.M., Becker, P.R., Gulland, F., Porter, B.J., Wise, S.A. Mar. Pollut. Bull. (2006) [Pubmed]
  23. Distribution of polychlorinated biphenyls, organochlorine pesticides and polybrominated diphenyl ethers in human umbilical cord serum, maternal serum and milk from Wielkopolska region, Poland. Jaraczewska, K., Lulek, J., Covaci, A., Voorspoels, S., Kaluba-Skotarczak, A., Drews, K., Schepens, P. Sci. Total Environ. (2006) [Pubmed]
  24. Impact of repeated exposure on the toxicokinetics of BDE 47 in mice. Staskal, D.F., Diliberto, J.J., Birnbaum, L.S. Toxicol. Sci. (2006) [Pubmed]
  25. Lack of effects of some individual polybrominated diphenyl ether (PBDE) and polychlorinated biphenyl (PCB) congeners on human lymphocyte functions in vitro. Fernlöf, G., Gadhasson, I., Pödra, K., Darnerud, P.O., Thuvander, A. Toxicol. Lett. (1997) [Pubmed]
  26. Polybrominated Diphenyl Ether (PBDE) Levels in an Expanded Market Basket Survey of U.S. Food and Estimated PBDE Dietary Intake by Age and Sex. Schecter, A., P??pke, O., Harris, T.R., Tung, K.C., Musumba, A., Olson, J., Birnbaum, L. Environ. Health Perspect. (2006) [Pubmed]
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