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Chemical Compound Review

AC1L9AV6     methyl-[[4-(propan-2- ylcarbamoyl)phenyl]me...

Synonyms:
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Disease relevance of Procarbazine hydrochloride

 

High impact information on Procarbazine hydrochloride

 

Chemical compound and disease context of Procarbazine hydrochloride

 

Biological context of Procarbazine hydrochloride

  • Procarbazine hydrochloride, and antineoplastic drug, was administered to pregnant rats from days 13 to 16 of gestation at doses of 0, 1, 5 and 15 mg per kg as part of a behavioural study [9].
 

Anatomical context of Procarbazine hydrochloride

 

Gene context of Procarbazine hydrochloride

 

Analytical, diagnostic and therapeutic context of Procarbazine hydrochloride

References

  1. Specific locus mutations induced in somatic cells of rats by orally and parenterally administered procarbazine. Maier, P., Zbinden, G. Science (1980) [Pubmed]
  2. The effect of enzyme-inducing antiseizure drugs on the pharmacokinetics and tolerability of procarbazine hydrochloride. Grossman, S.A., Carson, K.A., Batchelor, T.T., Lesser, G., Mikkelsen, T., Alavi, J.B., Phuphanich, S., Hammour, T., Fisher, J.D., Supko, J.G. Clin. Cancer Res. (2006) [Pubmed]
  3. Procarbazine carcinogenicity in methotrexate-treated or lipotrope-deficient male rats. Rogers, A.E., Akhtar, R., Zeisel, S.H. Carcinogenesis (1990) [Pubmed]
  4. A mutation affecting the lactate dehydrogenase locus Ldh-1 in the mouse. II. Mechanism of the LDH-A deficiency associated with hemolytic anemia. Pretsch, W., Merkle, S., Favor, J., Werner, T. Genetics (1993) [Pubmed]
  5. Procarbazine for non-Hodgkin's lymphoma. Chaar, B.T., Salem, P., Petruska, P.J. Leuk. Lymphoma (2006) [Pubmed]
  6. Specific unresponsiveness to fully allogeneic kidney allografts in rats induced by procarbazine hydrochloride and antilymphocyte serum. Al Mahdi, N., Hutchinson, I.V., Brent, L. Transplantation (1983) [Pubmed]
  7. A study on the mechanism of donor pretreatment: effect of procarbazine hydrochloride and methylprednisolone in immunocompetent cells. van der Linden, C.J., Buurman, W.A., Vegt, P.A., Greep, J.M., Jeekel, J. Transplantation (1981) [Pubmed]
  8. Chemotherapy of malignant glioma with CCNU alone and CCNU combined with vincristine sulfate and procarbazine hydrochloride. Shapiro, W.R., Young, D.F. Transactions of the American Neurological Association. (1976) [Pubmed]
  9. The neuroteratogenicity of procarbazine hydrochloride in the rat: histopathological and immunocytochemical aspects. Wright, J.A., Brickell, L., Foster, J. J. Comp. Pathol. (1989) [Pubmed]
  10. Specific unresponsiveness to skin allografts in mice. V. Synergy between donor tissue extract, procarbazine hydrochloride, and antilymphocyte serum in creating a long-lasting unresponsiveness mediated by suppressor T cells. Brent, L., Opara, S.C. Transplantation (1979) [Pubmed]
  11. Micronucleus evaluation in peripheral blood reticulocytes of mice treated with procarbazine hydrochloride or mitomycin C. Romagna, F., Matsumura, H., Watanabe, M., Kato, T., Shirasu, Y., Ohmori, K., Yamada, H., Sasaki, Y.F. Mutat. Res. (1992) [Pubmed]
  12. Detection of dominant enzyme mutants in mice: model studies for mutations in man. Pretsch, W., Charles, D.J. IARC Sci. Publ. (1984) [Pubmed]
  13. A mutation resulting in increased triosephosphate isomerase activity in Mus musculus. Merkle, S., Reitmeir, P., Pretsch, W. Genet. Res. (1991) [Pubmed]
  14. Specific unresponsiveness to skin allografts in mice. VI. Graft survival in mice pretreated with blood. Wood, P., Horsburgh, T., Brent, L. Transplantation (1981) [Pubmed]
  15. Application of an electrochemical detector to the determination of procarbazine hydrochloride by high-performance liquid chromatography. Rucki, R.J., Ross, A., Moros, S.A. J. Chromatogr. (1980) [Pubmed]
  16. Micronucleus test with procarbazine hydrochloride administered by intraperitoneal injection and oral gavage. Inouye, T., Imanishi, H., Watanabe, M., Sasaki, Y.F., Shirasu, Y., Ando, N., Ishii, S. Mutat. Res. (1989) [Pubmed]
 
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