Disease relevance of SODIUM PERBORATE

• OBJECTIVE: The purpose of this study was to evaluate the biocompatibility of the most used bleaching materials for pulpless teeth, sodium perborate and 30% hydrogen peroxide, in an experimental model of macrophages, through analysis of the adherence index and the cellular morphology [1].
• In one experimental group, the pulp chambers were acid etched with 50% phosphoric acid for 1 min to remove the smear layer prior to insertion of the 30% hydrogen peroxide/sodium perborate bleaching agents [2].

High impact information on SODIUM PERBORATE

• The response to oxidative stress in vitro (evaluated determining the parameters characterizing light emission from preparations stressed with sodium perborate) showed a substantial PB-induced increase in the susceptibility to oxidative challenge only in liver homogenate [3].
• (i) The XO-dependent luminescent signal related to the oxidation of luminol is dramatically enhanced in the presence of iron-EDTA complex and sodium perborate in alkaline buffer [4].
• Surface pH and bond strength of a self-etching primer/adhesive system to intracoronal dentin after application of hydrogen peroxide bleach with sodium perborate [5].
• Determination of trace trichlorfon by high performance liquid chromatography with UV detection based on its catalytic effect on sodium perborate oxidizing benzidine [6].
• Intracoronal "walking bleaching" (I) was performed after 24 hours of root canal treatment in the three remaining groups; no bleaching (IN); sodium perborate dissolved in 35% H2O2 (ISP-35H); and sodium perborate in distilled water (ISP-W) [7].

Chemical compound and disease context of SODIUM PERBORATE

• The purpose of this study was to examine histologically and radiographically the effect of a bleaching agent, a mixture of sodium perborate and superoxol (30% hydrogen peroxide), without a heat source on the cervical root surface and periodontal tissue of endodontically treated teeth of dogs [8].

Biological context of SODIUM PERBORATE

• The inhibitory effect of sodium perborate on macrophage adhesion further supports the concept that this agent is not implicated in external cervical root resorption associated with intracoronal bleaching [9].
• Disinfection methods included scrubbing with 4% chlorhexidine gluconate for 1 minute, immersion for 10 minutes in 1 of the tested disinfectant solutions (n=8) (3.78% sodium perborate, 4% chlorhexidine gluconate, or 1% sodium hypochorite), and immersion in water for 3 minutes [10].

Anatomical context of SODIUM PERBORATE

• The dentin surfaces on all specimens were bleached with a mixture of 30% hydrogen peroxide and sodium perborate in 100% humidity at 37 degrees C for one week [5].
• Evaluation of biocompatibility of sodium perborate and 30% hydrogen peroxide using the analysis of the adherence capacity and morphology of macrophages [1].
• A walking bleach of Superoxol and sodium perborate was placed in the pulp chamber for three treatments [11].
• A discolored, nonvital maxillary right central incisor was bleached with sodium perborate and water, used as a "walking" bleach [12].
• Extracted human teeth with intact crowns were discolored with human erythrocytes and bleached by sodium perborate mixed with either 30% hydrogen peroxide (group A), 3% hydrogen peroxide (group B), or water (group C) [13].

Associations of SODIUM PERBORATE with other chemical compounds

• MATERIALS AND METHODS: Two hundred seventy bovine teeth were assigned to 3 groups (n = 90): SP, paste of sodium perborate and water; CP, 37% carbamide peroxide; CO, control group (no treatment) [14].
• The enzyme was stable toward some detergents, sodium perborate, sodium triphosphate, sodium-n-dodecylbenzenesulfonate, and sodium dodecyl sulfate, at a concentration of 0.1% and pH 11.5 and 37 degrees C for 60 min [15].
• Rat liver homogenates were subjected to oxidative stress with sodium perborate, and the light signals, generated by a suitable system, containing luminol and compounds producing enhancement of light emission such as sodium benzoate and indophenol, were detected by a luminometer [16].
• Substance-specific input data which were used in this scenario were partly generic (e.g. LAS and sodium perborate tetrahydrate consumption figures for Germany) and partly (site-)specific data (e.g. half-life time for LAS elimination) [17].

Analytical, diagnostic and therapeutic context of SODIUM PERBORATE

• RESULTS: Results showed that sodium perborate neither increased the adherence index, nor altered the cellular morphology when compared to the control group [1].
• The efficacy of sodium perborate in maintenance of oral hygiene [18].
• In conclusion, the pH of bleaching pastes depends on the content of water of crystallization in sodium perborate, H2O2 concentration, and time of measurement [19].

References