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Chemical Compound Review

Bilirubin IX|A     3-[2-[[3-(2-carboxyethyl)-5- [(Z)-(3...

Synonyms: AC1NUZJX, (Z,Z)-Bilirubin, (Z,Z)-Bilirubin IXalpha, (4Z,15Z)-Bilirubin IXalpha
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Disease relevance of Hematoidin


High impact information on Hematoidin


Biological context of Hematoidin

  • Cervicovaginal smears obtained from two women, one at the 32nd week of pregnancy and the other at the immediate postpartum period, contained hematoidin crystals [9].

Anatomical context of Hematoidin

  • Previously underscribed phenomena include clinical evidence of fixed fetal position and a unique pattern of hemosiderin and hematoidin staining of the fetal membranes [10].

Associations of Hematoidin with other chemical compounds


Gene context of Hematoidin

  • After screening assay, 58 clones were identified which were producing antibodies not to albumin nor MBS, but to haptenic bilirubin-IX alpha [13].

Analytical, diagnostic and therapeutic context of Hematoidin


  1. Bilirubin photooxidation products in the urine of jaundiced neonates receiving phototherapy. Lightner, D.A., Linnane, W.P., Ahlfors, C.E. Pediatr. Res. (1984) [Pubmed]
  2. A yellow-stained human femur from Tell esh-Shuqafiya, Egypt: evidence of ancient trauma. Jones, R.N. Am. J. Phys. Anthropol. (1988) [Pubmed]
  3. Postoperative granulomas of the endometrium: histological features after endometrial ablation. Silvernagel, S.W., Harshbarger, K.E., Shevlin, D.W. Annals of diagnostic pathology. (1997) [Pubmed]
  4. The cytology of cerebrospinal fluid associated with neonatal intraventricular hemorrhage. Craver, R.D. Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association. (1996) [Pubmed]
  5. "Viable motheaten," a new allele at the motheaten locus. I. Pathology. Shultz, L.D., Coman, D.R., Bailey, C.L., Beamer, W.G., Sidman, C.L. Am. J. Pathol. (1984) [Pubmed]
  6. Site-specific water proton relaxation enhancement of iron(III) chelates noncovalently bound to human serum albumin. Jenkins, B.G., Armstrong, E., Lauffer, R.B. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. (1991) [Pubmed]
  7. Changes in the composition of bilirubin-IX isomers during human prenatal development. Yamaguchi, T., Nakajima, H. Eur. J. Biochem. (1995) [Pubmed]
  8. Synovial fluid crystals derived from erythrocyte degradation products. Tate, G.A., Schumacher, H.R., Reginato, A.J., Algeo, S.B., Gratwick, G.M., Di Battista, W.T. J. Rheumatol. (1992) [Pubmed]
  9. Hematoidin crystals in cervicovaginal smears. Report of two cases. Zaharopoulos, P., Wong, J.Y., Keagy, N. Acta Cytol. (1985) [Pubmed]
  10. Extramembranous pregnancy: maternal, placental, and perinatal implications. Perlman, M., Tennenbaum, A., Menashi, M., Ron, M., Ornoy, A. Obstetrics and gynecology. (1980) [Pubmed]
  11. On the interaction of polypeptides with bile salts or bilirubin-IX alpha. D'Alagni, M., D'Archivio, A.A., Giglio, E. Biopolymers (1993) [Pubmed]
  12. Epitope of 24G7 anti-bilirubin monoclonal antibody. Yamaguchi, T., Shioji, I., Sugimoto, A., Komoda, Y., Nakajima, H. Biochim. Biophys. Acta (1996) [Pubmed]
  13. Anti-bilirubin monoclonal antibody. III. Preparation and properties of monoclonal antibodies to unconjugated bilirubin-IX alpha. Okamura, Y., Yamazaki, M., Yamaguchi, T., Komoda, Y., Sugimoto, A., Nakajima, H. Biochim. Biophys. Acta (1991) [Pubmed]
  14. Deconjugation of bilirubin-IX alpha glucuronides: a physiologic role of hepatic microsomal beta-glucuronidase. Whiting, J.F., Narciso, J.P., Chapman, V., Ransil, B.J., Swank, R.T., Gollan, J.L. J. Biol. Chem. (1993) [Pubmed]
  15. Demonstration of a geometric isomer of bilirubin-IX alpha in the serum of a hyperbilirubinaemic newborn infant and the mechanism of jaundice phototherapy. Onishi, S., Isobe, K., Itoh, S., Kawade, N., Sugiyama, S. Biochem. J. (1980) [Pubmed]
  16. High-pressure liquid chromatographic analysis of anaerobic photoproducts of bilirubin-IX alpha in vitro and its comparison with photoproducts in vivo. Onishi, S., Kawade, N., Itoh, S., Isobe, K., Sugiyama, S. Biochem. J. (1980) [Pubmed]
  17. Crystalline bodies in cervical smears. Clinicocytologic correlation. Minassian, H., Schinella, R., Reilly, J.C. Acta Cytol. (1993) [Pubmed]
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