Chemical Compound Review:
DOTARIZINE 1-benzhydryl-4-[3-(2-phenyl- 1,3-dioxolan-2...
Synonyms:
Dotarizina, Dotarizinum, SureCN333044, AG-H-38356, CHEMBL2106316, ...
- Novel antimigraineur dotarizine releases Ca2+ from caffeine-sensitive Ca2+ stores of chromaffin cells. Novalbos, J., Abad-Santos, F., Zapater, P., Alvarez, J., Alonso, M.T., Montero, M., García, A.G. Br. J. Pharmacol. (1999)
- Albumin prevents mitochondrial depolarization and apoptosis elicited by endoplasmic reticulum calcium depletion of neuroblastoma cells. Gallego-Sandín, S., Novalbos, J., Rosado, A., Cano-Abad, M.F., Arias, E., Abad-Santos, F., García, A.G. Eur. J. Pharmacol. (2005)
- Regional differences of cerebrovascular reactivity effected by calcium channel blocker - dotarizine. Kuridze, N., Czernicki, Z., Jarus-Dziedzic, K., Jurkiewicz, J., Cervos-Navarro, J. J. Neurol. Sci. (2000)
- The effect of Dotarizine (Ca2+ channel blocker) on cerebral vessel reactivity in animals subjected to hyperventilation and anoxia. Czernicki, Z., Kuridze, N., Jurkiewicz, J., Cervós-Navarro, J. Acta Neurochir. Suppl. (1997)
- The effect of Dotarizine--(Ca2+ channel blocker)--on vascular reactivity and ultrastructure of cerebral capillaries in animals subjected to anoxia. Kuridze, N., Gajkowska, B., Czernicki, Z., Jurkiewicz, J., Cervos-Navarro, J. Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences. (1998)
- Effects on nociception of the Ca2+ and 5-HT antagonist dotarizine and other 5-HT receptor agonists and antagonists. Belcheva, S., Petkov, V.D., Konstantinova, E., Petkov, V.V., Boyanova, E. Acta physiologica et pharmacologica Bulgarica. (1995)
- Anxiolytic effects of dotarizine, a possible antimigraine drug. Petkov, V.D., Belcheva, S., Konstantinova, E. Methods and findings in experimental and clinical pharmacology. (1995)
- Dotarizine versus flunarizine as calcium antagonists in chromaffin cells. Villarroya, M., Gandía, L., Lara, B., Albillos, A., López, M.G., García, A.G. Br. J. Pharmacol. (1995)
- Antimigraine dotarizine blocks P/Q Ca2+ channels and exocytosis in a voltage-dependent manner in chromaffin cells. Ruiz-Nuño, A., Mayorgas, I., Hernández-Guijo, J.M., Olivares, R., García, A.G., Gandía, L. Eur. J. Pharmacol. (2003)
- Mechanisms of blockade by the novel migraine prophylactic agent, dotarizine, of various brain and peripheral vessel contractility. Ruiz-Nuño, A., Villarroya, M., Cano-Abad, M., Rosado, A., Balfagón, G., López, M.G., García, A.G. Eur. J. Pharmacol. (2001)
- Serotonergic effects of dotarizine in coronary artery and in oocytes expressing 5-HT2 receptors. Montiel, C., Herrero, C.J., García-Palomero, E., Renart, J., García, A.G., Lomax, R.B. Eur. J. Pharmacol. (1997)
- Effects of dotarizine on peripheral and pulmonary circulation and cardiac dynamics in dogs. Cartheuser, C.F., Brasó, A., Sacristán, A., Ortiz, J.A. Pharmacology (1994)
- Clinical pharmacokinetics and tolerability of dotarizine in healthy subjects after single and multiple oral administration. Farré, M., Roset, P.N., Llorente, M., Márquez, M., Albet, C., Pérez, J.A., Herrero, E., Ortíz, J.A. Methods and findings in experimental and clinical pharmacology. (1997)
- Effects of dotarizine on 45Ca2+ movements and contractile responses in vascular smooth muscle. Tejerina, T., Chulia, T., Gonzalez, P. Eur. J. Pharmacol. (1993)
- Ba(2+)-induced chromaffin cell death: cytoprotection by Ca(2+) channel antagonists. Cano-Abad, M.F., García, A.G., Sánchez-García, P., López, M.G. Eur. J. Pharmacol. (2000)
- Effects of agonists and antagonists of some serotonin-receptor subtypes on memory and their modulation by the 5-HT-uptake inhibitor fluoxetine. Petkov, V.D., Kehayov, R. Acta physiologica et pharmacologica Bulgarica. (1994)
- Vasostabilizing effect of Dotarizine (Ca(2+)-channel blocker) on cerebrovascular reactivity in rabbits. Kuridze, N., Czernicki, Z., Jarus-Dziedzic, K., Jurkiewicz, J., Cervos-Navarro, J. Neurol. Res. (2000)
- Effect of oral administration of dotarizine on cerebrovasculature subjected to constriction followed by dilatation in rabbits. Jarus-Dziedzic, K., Czernicki, Z., Cervos-Navarro, J., Jurkiewicz, J. Acta neurochirurgica. (1999)