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Chemical Compound Review

TEOS     tetraethoxysilane

Synonyms: Dynasil A, Silikan L, ETHYL SILICATE, Etylu krzemian, HSDB 534, ...
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Disease relevance of tetraethoxysilane


High impact information on tetraethoxysilane


Chemical compound and disease context of tetraethoxysilane


Biological context of tetraethoxysilane


Anatomical context of tetraethoxysilane

  • To control swelling of quaternized chitosan (q-Chito) membranes, mixtures of q-Chito as an organic component and tetraethoxysilane (TEOS) as an inorganic component were prepared using the sol-gel reaction, and novel q-Chito/TEOS hybrid membranes were formed [10].
  • After cleaning, fiber samples were immersed into tetraethoxysilane (TEOS) at room temperature for 1 h, and then individual fiber samples were soaked into a simulated body fluid (SBF) solution,1 and removed after 5, 10, 15, and 20 days [11].

Associations of tetraethoxysilane with other chemical compounds


Gene context of tetraethoxysilane

  • To clarify the acute and subchronic inhalation toxicity of tetraethoxysilane [TEOS, Si(OC2H5)4], groups of ten male ICR mice (SPF grade) were exposed to 1000 ppm TEOS for 1,2,4 or 8 h (acute inhalation study), or to 200 ppm of TEOS for 6 h/day, 5 days/week, for 2 or 4 weeks (subchronic inhalation study) [1].
  • METHODS: The modified amorphous calcium phosphates were synthesized at pH 10.5 by mixing 800 mmol/L Ca(NO3)2 solutions and either 250 mmol/L zirconylchloride (ZrOCl2) or 4.4 mol/L tetraethoxysilane (TEOS) solutions with solutions containing 525 mmol/L Na2HPO4 and 11 mmol/L Na4P2O7 [17].
  • We report the application of 29Si and 27Al magic angle spinning nuclear magnetic resonance (MAS NMR) studies on building stones from historical monuments to obtain direct information about the degree of degradation and to observe the changes in the consolidated material after treatment with tetraethoxysilane (TEOS) [18].
  • TEM/EDS analyses have shown that tetraethyl orthosilicate (TEOS) may be less appropriate as a silicon source during the syntheses of cobalt-containing mesoporous materials, because the distribution of cobalt throughout the framework may become uneven [19].

Analytical, diagnostic and therapeutic context of tetraethoxysilane


  1. Acute and subchronic inhalation toxicity of tetraethoxysilane (TEOS) in mice. Nakashima, H., Omae, K., Sakai, T., Yamazaki, K., Sakurai, H. Arch. Toxicol. (1994) [Pubmed]
  2. Mineralization of SaOS-2 cells on enzymatically (silicatein) modified bioactive osteoblast-stimulating surfaces. Schröder, H.C., Boreiko, O., Krasko, A., Reiber, A., Schwertner, H., Müller, W.E. Journal of biomedical materials research. Part B, Applied biomaterials. (2005) [Pubmed]
  3. Photochemical incorporation of silver quantum dots in monodisperse silica colloids for photonic crystal applications. Wang, W., Asher, S.A. J. Am. Chem. Soc. (2001) [Pubmed]
  4. Octyl-functionalized hybrid silica monolithic column for reversed-phase capillary electrochromatography. Yan, L.J., Zhang, Q.H., Feng, Y.Q., Zhang, W.B., Li, T., Zhang, L.H., Zhang, Y.K. Journal of chromatography. A. (2006) [Pubmed]
  5. Fluorescence probing investigation of the mechanism of formation of MSU-type mesoporous silica prepared in fluoride medium. Lesaint, C., Lebeau, B., Marichal, C., Patarin, J., Zana, R. Langmuir : the ACS journal of surfaces and colloids. (2005) [Pubmed]
  6. Optimization of dye-doped silica nanoparticles prepared using a reverse microemulsion method. Bagwe, R.P., Yang, C., Hilliard, L.R., Tan, W. Langmuir : the ACS journal of surfaces and colloids. (2004) [Pubmed]
  7. Apatite nucleation on silica surface: a zeta potential approach. Coreño, J., Martínez, A., Bolarín, A., Sánchez, F. J. Biomed. Mater. Res. (2001) [Pubmed]
  8. Toxicity of intraperitoneally administrated silicon tetraalkoxides in male ICR mice. Nakashima, H., Omae, K., Yamazaki, K., Sakai, T., Sakurai, H. The Keio journal of medicine. (1993) [Pubmed]
  9. Kinetics and thermodynamics of bromophenol blue adsorption by a mesoporous hybrid gel derived from tetraethoxysilane and bis(trimethoxysilyl)hexane. You, L., Wu, Z., Kim, T., Lee, K. Journal of colloid and interface science. (2006) [Pubmed]
  10. Dehydration of an ethanol/water azeotrope by novel organic-inorganic hybrid membranes based on quaternized chitosan and tetraethoxysilane. Uragami, T., Katayama, T., Miyata, T., Tamura, H., Shiraiwa, T., Higuchi, A. Biomacromolecules (2004) [Pubmed]
  11. Surface modifications of alumina-silica glass fiber. Andrade, A.L., Ferreira, J.M., Domingues, R.Z. Journal of biomedical materials research. Part B, Applied biomaterials. (2004) [Pubmed]
  12. Preparation of stationary phases for open-tubular capillary electrochromatography using the sol-gel method. Constantin, S., Freitag, R. Journal of chromatography. A. (2000) [Pubmed]
  13. Deformable hollow hybrid silica/siloxane colloids by emulsion templating. Zoldesi, C.I., van Walree, C.A., Imhof, A. Langmuir : the ACS journal of surfaces and colloids. (2006) [Pubmed]
  14. Sol-gel modification of silicone to induce apatite-forming ability. Oyane, A., Nakanishi, K., Kim, H.M., Miyaji, F., Kokubo, T., Soga, N., Nakamura, T. Biomaterials (1999) [Pubmed]
  15. Surface modification of hydroxyapatite. Part II. Silica. Borum, L., Wilson, O.C. Biomaterials (2003) [Pubmed]
  16. Apatite-forming ability and mechanical properties of PTMO-modified CaO-SiO2 hybrids prepared by sol-gel processing: effect of CaO and PTMO contents. Miyata, N., Fuke, K., Chen, Q., Kawashita, M., Kokubo, T., Nakamura, T. Biomaterials (2002) [Pubmed]
  17. Improved properties of amorphous calcium phosphate fillers in remineralizing resin composites. Skrtic, D., Antonucci, J.M., Eanes, E.D. Dental materials : official publication of the Academy of Dental Materials. (1996) [Pubmed]
  18. Application of 29Si and 27Al magic angle spinning nuclear magnetic resonance to studies of the building materials of historical monuments. Cervantes, J., Mendoza-Díaz, G., Alvarez-Gasca, D.E., Martinez-Richa, A. Solid state nuclear magnetic resonance. (1999) [Pubmed]
  19. Spectroscopic characterization of cobalt-containing mesoporous materials. Vrålstad, T., Glomm, W.R., Rønning, M., Dathe, H., Jentys, A., Lercher, J.A., Oye, G., Stöcker, M., Sjöblom, J. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2006) [Pubmed]
  20. Co-immobilization of glucose oxidase and hexokinase on silicate hybrid sol-gel membrane for glucose and ATP detections. Liu, S., Sun, Y. Biosensors & bioelectronics (2007) [Pubmed]
  21. Colloidal aggregation phenomena: Spatial structuring of TEOS-derived silica aerogels. Vinogradova, E., Estrada, M., Moreno, A. Journal of colloid and interface science. (2006) [Pubmed]
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