Chemical Compound Review:
Azauracil 2H-1,2,4-triazine-3,5-dione
Synonyms:
zlchem 198, PubChem20340, SureCN88056, NSC-3425, ACMC-1BSXW, ...
Dow,
Schneider,
Paight,
Hank,
Chiang,
Cornelius,
Lee,
Newsome,
Swick,
Spitzer,
Hargrove,
Patterson,
Pandit,
Chrunyk,
LeMotte,
Danley,
Rosner,
Ammirati,
Simons,
Schulte,
Tate,
DaSilva-Jardine,
Van Wauwe,
Aerts,
Cools,
Deroose,
Freyne,
Goossens,
Hermans,
Lacrampe,
Van Genechten,
Van Gerven,
Van Nyen,
Woodage,
Basrai,
Baxevanis,
Hieter,
Collins,
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- Increase in arginine and citrulline production by 6-azauracil-resistant mutants of Bacillus subtilis. Kato, J., Kisumi, M., Takagi, T., Chibata, I. Appl. Environ. Microbiol. (1977)
- Identification of R146225 as a novel, orally active inhibitor of interleukin-5 biosynthesis. Van Wauwe, J., Aerts, F., Cools, M., Deroose, F., Freyne, E., Goossens, J., Hermans, B., Lacrampe, J., Van Genechten, H., Van Gerven, F., Van Nyen, G. J. Pharmacol. Exp. Ther. (2000)
- A bacterial mutagenicity study of rivanol, an acridine derivative used as an abortifacient. Wugmeister, M., Summers, W.C. The Yale journal of biology and medicine. (1983)
- The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability. Chávez, S., Aguilera, A. Genes Dev. (1997)
- Altered nucleosome occupancy and histone H3K4 methylation in response to 'transcriptional stress'. Zhang, L., Schroeder, S., Fong, N., Bentley, D.L. EMBO J. (2005)
- The Paf1 complex physically and functionally associates with transcription elongation factors in vivo. Squazzo, S.L., Costa, P.J., Lindstrom, D.L., Kumer, K.E., Simic, R., Jennings, J.L., Link, A.J., Arndt, K.M., Hartzog, G.A. EMBO J. (2002)
- Characterization of the CHD family of proteins. Woodage, T., Basrai, M.A., Baxevanis, A.D., Hieter, P., Collins, F.S. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Method for isolation of auxotrophs in the methanogenic archaebacteria: role of the acetyl-CoA pathway of autotrophic CO2 fixation in Methanococcus maripaludis. Ladapo, J., Whitman, W.B. Proc. Natl. Acad. Sci. U.S.A. (1990)
- The Rpb6 subunit of fission yeast RNA polymerase II is a contact target of the transcription elongation factor TFIIS. Ishiguro, A., Nogi, Y., Hisatake, K., Muramatsu, M., Ishihama, A. Mol. Cell. Biol. (2000)
- Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Krogan, N.J., Kim, M., Tong, A., Golshani, A., Cagney, G., Canadien, V., Richards, D.P., Beattie, B.K., Emili, A., Boone, C., Shilatifard, A., Buratowski, S., Greenblatt, J. Mol. Cell. Biol. (2003)
- Genetic interaction between transcription elongation factor TFIIS and RNA polymerase II. Archambault, J., Lacroute, F., Ruet, A., Friesen, J.D. Mol. Cell. Biol. (1992)
- TFIIS enhances transcriptional elongation through an artificial arrest site in vivo. Kulish, D., Struhl, K. Mol. Cell. Biol. (2001)
- Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics. Dow, R.L., Schneider, S.R., Paight, E.S., Hank, R.F., Chiang, P., Cornelius, P., Lee, E., Newsome, W.P., Swick, A.G., Spitzer, J., Hargrove, D.M., Patterson, T.A., Pandit, J., Chrunyk, B.A., LeMotte, P.K., Danley, D.E., Rosner, M.H., Ammirati, M.J., Simons, S.P., Schulte, G.K., Tate, B.F., DaSilva-Jardine, P. Bioorg. Med. Chem. Lett. (2003)
- Bur1 kinase is required for efficient transcription elongation by RNA polymerase II. Keogh, M.C., Podolny, V., Buratowski, S. Mol. Cell. Biol. (2003)
- Functional interaction between TFIIB and the Rpb2 subunit of RNA polymerase II: implications for the mechanism of transcription initiation. Chen, B.S., Hampsey, M. Mol. Cell. Biol. (2004)
- Biosynthesis of uridine monophosphate in Plasmodium berghei. O'Sullivan, W.J., Ketley, K. Ann. Trop. Med. Parasitol. (1980)
- 6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae. Exinger, F., Lacroute, F. Curr. Genet. (1992)
- Cleavage, but not read-through, stimulation activity is responsible for three biologic functions of transcription elongation factor S-II. Ubukata, T., Shimizu, T., Adachi, N., Sekimizu, K., Nakanishi, T. J. Biol. Chem. (2003)
- RNA polymerase II subunit Rpb9 regulates transcription elongation in vivo. Hemming, S.A., Jansma, D.B., Macgregor, P.F., Goryachev, A., Friesen, J.D., Edwards, A.M. J. Biol. Chem. (2000)
- Saccharomyces cerevisiae transcription elongation mutants are defective in PUR5 induction in response to nucleotide depletion. Shaw, R.J., Reines, D. Mol. Cell. Biol. (2000)
- mRNA capping enzyme activity is coupled to an early transcription elongation. Kim, H.J., Jeong, S.H., Heo, J.H., Jeong, S.J., Kim, S.T., Youn, H.D., Han, J.W., Lee, H.W., Cho, E.J. Mol. Cell. Biol. (2004)
- Anticoccidial derivatives of 6-azauracil. 4. A 1000-fold enhancement of potency by phenyl sulfide and phenyl sulfone side chains. Miller, M.W., Mylari, B.L., Howes, H.L., Figdor, S.K., Lynch, M.J., Lynch, J.E., Gupta, S.K., Chappel, L.R., Koch, R.C. J. Med. Chem. (1981)
- Anticoccidial derivatives of 6-azauracil. 1. Enhancement of activity by benzylation of nitrogen-1. Observations on the design of nucleotide analogues in chemotherapy. Mylari, B.L., Miller, M.W., Howes, H.L., Figdor, S.K., Lynch, J.E., Koch, R.C. J. Med. Chem. (1977)
- Potential carcinogenicity of the synthetic 1,3,6-triazine (6-azapyrimidine) nucleic acid analogues determined by DC polarography. II. Nucleosides of 6-azauracil. Novotný, L., Vachálková, A., Pískala, A. Neoplasma (1999)