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Chemical Compound Review

NMOR     4-nitrosomorpholine

Synonyms: NSC-139, CCRIS 473, NSC139, CHEMBL165908, LS-254, ...
 
 
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Disease relevance of Nitrosomorpholine

 

Psychiatry related information on Nitrosomorpholine

 

High impact information on Nitrosomorpholine

 

Chemical compound and disease context of Nitrosomorpholine

 

Biological context of Nitrosomorpholine

 

Anatomical context of Nitrosomorpholine

 

Associations of Nitrosomorpholine with other chemical compounds

 

Gene context of Nitrosomorpholine

 

Analytical, diagnostic and therapeutic context of Nitrosomorpholine

References

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  14. Bacterial formation of N-nitroso compounds from administered precursors in the rat stomach after omeprazole-induced achlorhydria. Calmels, S., Béréziat, J.C., Ohshima, H., Bartsch, H. Carcinogenesis (1991) [Pubmed]
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  25. A sensitive method for detecting in vivo formation of N-nitrosomorpholine and its application to rats given low doses of morpholine and sodium nitrite. Hecht, S.S., Morrison, J.B. Cancer Res. (1984) [Pubmed]
  26. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Grasl-Kraupp, B., Ruttkay-Nedecky, B., Koudelka, H., Bukowska, K., Bursch, W., Schulte-Hermann, R. Hepatology (1995) [Pubmed]
  27. Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors. Cortinovis, C., Klimek, F., Nogueira, E. Am. J. Pathol. (1991) [Pubmed]
  28. Differential expression of key enzymes of energy metabolism in preneoplastic and neoplastic rat liver lesions induced by N-nitrosomorpholine and dehydroepiandrosterone. Mayer, D., Metzger, C., Leonetti, P., Beier, K., Benner, A., Bannasch, P. Int. J. Cancer (1998) [Pubmed]
  29. Enhancement by isoproterenol of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats. Uehara, H., Nakaizumi, A., Baba, M., Iishi, H., Tatsuta, M. Int. J. Cancer (1993) [Pubmed]
  30. Predicting the mutagenicity of tobacco-related N-nitrosamines in humans using 11 strains of Salmonella typhimurium YG7108, each coexpressing a form of human cytochrome P450 along with NADPH-cytochrome P450 reductase. Fujita, K., Kamataki, T. Environ. Mol. Mutagen. (2001) [Pubmed]
  31. Role of transforming growth factor alpha and prostaglandins in preferential growth of preneoplastic rat hepatocytes. Hufnagl, K., Parzefall, W., Marian, B., Käfer, M., Bukowska, K., Schulte-Hermann, R., Grasl-Kraupp, B. Carcinogenesis (2001) [Pubmed]
  32. Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes. Masui, T., Nakanishi, H., Inada, K., Imai, T., Mizoguchi, Y., Yada, H., Futakuchi, M., Shirai, T., Tatematsu, M. Cancer Lett. (1997) [Pubmed]
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  34. Inhibition by somatostatin of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats. Nakaizumi, A., Uehara, H., Baba, M., Iishi, H., Tatsuta, M. Carcinogenesis (1993) [Pubmed]
  35. Cleavage of poly(ADP-ribose) transferase during p53-independent apoptosis in rat liver after treatment with N-nitrosomorpholine and cyproterone acetate. Weşierska-Gadek, J., Bugajska-Schretter, A., Löw-Baselli, A., Grasl-Kraupp, B. Mol. Carcinog. (1999) [Pubmed]
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