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Chemical Compound Review

Bergamol     3,7-dimethylocta-1,6-dien-3-yl ethanoate

Synonyms: Bergamiol, L2807_ALDRICH, CHEMBL502773, HSDB 644, NSC-2138, ...
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Disease relevance of Bergamol

  • Detection of a new enzyme for stereoselective hydrolysis of linalyl acetate using simple plate assays for the characterization of cloned esterases from Burkholderia gladioli [1].
  • The effects of equi-molar doses of linalyl acetate on local edema were less relevant and more delayed than that of the corresponding alcohol [2].

High impact information on Bergamol


Biological context of Bergamol

  • The use of 1-hydroxypyrene-3,6,8-trisulfonic acid (HPTS-) esters and linalyl acetate for these assays clearly allowed to discriminate substrate specificities for two different cloned esterases, EP6 and EP10 [1].
  • The drug release kinetics of two substances, LLA and BZC, are observed, in showing a burst effect, then a diffusion process, which can be modelled assuming that the particles are homogeneous spheres [8].

Anatomical context of Bergamol


Associations of Bergamol with other chemical compounds


Gene context of Bergamol


  1. Detection of a new enzyme for stereoselective hydrolysis of linalyl acetate using simple plate assays for the characterization of cloned esterases from Burkholderia gladioli. Schlacher, A., Stanzer, T., Osprian, I., Mischitz, M., Klingsbichel, E., Faber, K., Schwab, H. J. Biotechnol. (1998) [Pubmed]
  2. Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Peana, A.T., D'Aquila, P.S., Panin, F., Serra, G., Pippia, P., Moretti, M.D. Phytomedicine (2002) [Pubmed]
  3. Mechanisms of antibacterial action of three monoterpenes. Trombetta, D., Castelli, F., Sarpietro, M.G., Venuti, V., Cristani, M., Daniele, C., Saija, A., Mazzanti, G., Bisignano, G. Antimicrob. Agents Chemother. (2005) [Pubmed]
  4. A molecular mechanism of enantiorecognition of tertiary alcohols by carboxylesterases. Henke, E., Bornscheuer, U.T., Schmid, R.D., Pleiss, J. Chembiochem (2003) [Pubmed]
  5. Cutaneous absorption and elimination of three acyclic terpenes--in vitro studies. Cal, K., Sznitowska, M. Journal of controlled release : official journal of the Controlled Release Society. (2003) [Pubmed]
  6. Comparison of different extraction methods for the analysis of fragrances from Lavandula species by gas chromatography-mass spectrometry. Kim, N.S., Lee, D.S. Journal of chromatography. A. (2002) [Pubmed]
  7. Linalyl acetate as a major ingredient of lavender essential oil relaxes the rabbit vascular smooth muscle through dephosphorylation of myosin light chain. Koto, R., Imamura, M., Watanabe, C., Obayashi, S., Shiraishi, M., Sasaki, Y., Azuma, H. J. Cardiovasc. Pharmacol. (2006) [Pubmed]
  8. Evaluation of gliadins nanoparticles as drug delivery systems: a study of three different drugs. Duclairoir, C., Orecchioni, A.M., Depraetere, P., Osterstock, F., Nakache, E. International journal of pharmaceutics. (2003) [Pubmed]
  9. Anticonflict effects of lavender oil and identification of its active constituents. Umezu, T., Nagano, K., Ito, H., Kosakai, K., Sakaniwa, M., Morita, M. Pharmacol. Biochem. Behav. (2006) [Pubmed]
  10. Acaricidal agents of natural origin against Psoroptes cuniculi. Perrucci, S., Cioni, P.L., Flamini, G., Morelli, I., Macchioni, G. Parassitologia (1994) [Pubmed]
  11. Chemical and biological diversity of Bergamot (Citrus bergamia) in relation to environmental factors. Statti, G.A., Conforti, F., Sacchetti, G., Muzzoli, M., Agrimonti, C., Menichini, F. Fitoterapia (2004) [Pubmed]
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