Disease relevance of Rhodinol

• Pseudomonas aeruginosa W51D is able to grow by using branched-chain dodecylbenzene sulfonates (B-DBS) or the terpenic alcohol citronellol as a sole source of carbon [1].
• In addition, administration of citronellol showed protection in the pentylenetetrazol and picrotoxin tests by increasing the latency of clonic seizures [2].
• The authors suggest the introduction of a mixture of two essential oils (citronellol and cassia) for consecutive testing of patients with dermatitis [3].

High impact information on Rhodinol

• Experiments were carried out to construct pseudomonad strains capable of the biodegradation of certain recalcitrant branched hydrocarbons via a combination of alkane and citronellol degradative pathways [4].
• In the case of Pseudomonas citronellolis, sensitivity to isoprenols is reduced by prior induction of the isoprenoid degradative pathway via either growth on succinate in the presence of citronellol or growth on citronellic acid [5].
• Taken together, our results demonstrated an anticonvulsant activity of the citronellol that could be, at least in part, explained by the diminution of the action potential amplitude [2].
• Pseudomonas aeruginosa is able to grow on acyclic monoterpenes (citronellol, citronellate, geraniol and geranylate), and on other methyl-branched compounds such as leucine or isovalerate [6].
• Utilization of geraniol is dependent on molybdenum in Pseudomonas aeruginosa: evidence for different metabolic routes for oxidation of geraniol and citronellol [7].

Biological context of Rhodinol

• Biotransformation of citronellol by the basidiomycete Cystoderma carcharias in an aerated-membrane bioreactor [8].
• The strain also exhibited excellent resistance to high concentrations of citronellol, i.e., it could maintain metabolism and enantioselective acetylation even in the presence of 30% citronellol [9].
• The pretreated lipase is used to catalyze esterification between citronellol and acetic acid in a medium of n-hexane [10].
• These diethers exhibited oviposition deterrent and developmental inhibition activities of greater magnitudes than the compounds based on citronellol reported in Part I of this paper [11].
• It would appear that these monoterpenoids are synthesised (via cyt P450 hydroxylation) from different precursors in different plant species, namely geraniol, its isomer nerol, or the related monoterpenoid, citronellol [12].

Associations of Rhodinol with other chemical compounds

• Saccharomyces cerevisiae and Kluyveromyces lactis reduced geraniol into citronellol, whilst all three yeasts produced linalool from both geraniol and nerol [13].
• Trials for determining the minimum inhibitory concentration (MIC) of these oils revealed that geraniol, nerol and citronellol were effective at 500 ppm, while thymol and cinnamaldehyde were highly effective at doses as low as 250 and 200 ppm, respectively [14].
• The absolute configurations of citronellol, 2,3-dihydrofarnesol, and 2,3-dihydrofarnesal in male marking pheromones of seven species of bumblebees and cuckoo bumblebees were determined by enantioselective gas chromatography on a capillary column coated with 60% heptakis(2,3-di-O-acetyl-6-O-TBDMS)-beta-cyclodextrin in polysiloxane PS 268 [15].
• AIMS: To determine the effects of herbal essential oils on Trichophyton spp. growth and to evaluate the effects of Pelargonium graveolens oil and its main components citronellol and geraniol combined with ketoconazole against Trichophyton spp [16].
• The addition of geraniol to cell suspension cultures of Citrus limon resulted in the rapid formation of nerol, citronellol, geranic acid and citronellic acid [17].

References