Gene Review:
AKAP8 - A kinase (PRKA) anchor protein 8
Homo sapiens
Synonyms:
A-kinase anchor protein 8, A-kinase anchor protein 95 kDa, AKAP 95, AKAP-8, AKAP-95, ...
- Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95. Eide, T., Coghlan, V., Orstavik, S., Holsve, C., Solberg, R., Skâlhegg, B.S., Lamb, N.J., Langeberg, L., Fernandez, A., Scott, J.D., Jahnsen, T., Taskén, K. Exp. Cell Res. (1998)
- Protein kinase A associates with HA95 and affects transcriptional coactivation by Epstein-Barr virus nuclear proteins. Han, I., Xue, Y., Harada, S., Orstavik, S., Skalhegg, B., Kieff, E. Mol. Cell. Biol. (2002)
- A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Li, Y., Kao, G.D., Garcia, B.A., Shabanowitz, J., Hunt, D.F., Qin, J., Phelan, C., Lazar, M.A. Genes Dev. (2006)
- A kinase-anchoring protein (AKAP)95 recruits human chromosome-associated protein (hCAP)-D2/Eg7 for chromosome condensation in mitotic extract. Steen, R.L., Cubizolles, F., Le Guellec, K., Collas, P. J. Cell Biol. (2000)
- Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication. Eide, T., Taskén, K.A., Carlson, C., Williams, G., Jahnsen, T., Taskén, K., Collas, P. J. Biol. Chem. (2003)
- The A-kinase-anchoring protein AKAP95 is a multivalent protein with a key role in chromatin condensation at mitosis. Collas, P., Le Guellec, K., Taskén, K. J. Cell Biol. (1999)
- A-kinase anchoring proteins interact with phosphodiesterases in T lymphocyte cell lines. Asirvatham, A.L., Galligan, S.G., Schillace, R.V., Davey, M.P., Vasta, V., Beavo, J.A., Carr, D.W. J. Immunol. (2004)
- Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis. Landsverk, H.B., Carlson, C.R., Steen, R.L., Vossebein, L., Herberg, F.W., Taskén, K., Collas, P. J. Cell. Sci. (2001)
- Identification, cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95. Orstavik, S., Eide, T., Collas, P., Han, I.O., Taskén, K., Kieff, E., Jahnsen, T., Skålhegg, B.S. Biol. Cell (2000)
- Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting. Eide, T., Carlson, C., Taskén, K.A., Hirano, T., Taskén, K., Collas, P. EMBO Rep. (2002)
- AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex. Furusawa, M., Taira, T., Iguchi-Ariga, S.M., Ariga, H. J. Biol. Chem. (2002)
- A-kinase-anchoring protein AKAP95 is targeted to the nuclear matrix and associates with p68 RNA helicase. Akileswaran, L., Taraska, J.W., Sayer, J.A., Gettemy, J.M., Coghlan, V.M. J. Biol. Chem. (2001)