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Map1a  -  microtubule-associated protein 1 A

Mus musculus

Synonyms: 6330416M19Rik, AI853608, MAP-1A, Microtubule-associated protein 1A, Mtap-1, ...
 
 
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Disease relevance of Mtap1a

 

High impact information on Mtap1a

 

Biological context of Mtap1a

 

Anatomical context of Mtap1a

 

Associations of Mtap1a with chemical compounds

  • Data collected from yeast two-hybrid assays of various MAP1A domains confirmed that the interaction of LC2 and NH2-terminal of MAP1A heavy chain is important for microtubule binding [8].
  • Here, we identified, by double-immunofluorescent labeling, MAP1A isoform and serotonin 5-HT(2A) receptor distribution [9].
 

Other interactions of Mtap1a

 

Analytical, diagnostic and therapeutic context of Mtap1a

References

  1. Microtubule-associated protein 1A is a modifier of tubby hearing (moth1). Ikeda, A., Zheng, Q.Y., Zuberi, A.R., Johnson, K.R., Naggert, J.K., Nishina, P.M. Nat. Genet. (2002) [Pubmed]
  2. Genetic modification of retinal degeneration in tubby mice. Ikeda, A., Naggert, J.K., Nishina, P.M. Exp. Eye Res. (2002) [Pubmed]
  3. Somatostatin receptors in wildtype and somatostatin deficient mice and their involvement in nitric oxide physiology in the retina. Mastrodimou, N., Vasilaki, A., Papadioti, A., Low, M.J., Hoyer, D., Thermos, K. Neuropeptides (2006) [Pubmed]
  4. Synthesis, axonal transport, and turnover of the high molecular weight microtubule-associated protein MAP 1A in mouse retinal ganglion cells: tubulin and MAP 1A display distinct transport kinetics. Nixon, R.A., Fischer, I., Lewis, S.E. J. Cell Biol. (1990) [Pubmed]
  5. A casein kinase II-related activity is involved in phosphorylation of microtubule-associated protein MAP-1B during neuroblastoma cell differentiation. Díaz-Nido, J., Serrano, L., Méndez, E., Avila, J. J. Cell Biol. (1988) [Pubmed]
  6. Genetic modification of hearing in tubby mice: evidence for the existence of a major gene (moth1) which protects tubby mice from hearing loss. Ikeda, A., Zheng, Q.Y., Rosenstiel, P., Maddatu, T., Zuberi, A.R., Roopenian, D.C., North, M.A., Naggert, J.K., Johnson, K.R., Nishina, P.M. Hum. Mol. Genet. (1999) [Pubmed]
  7. Microtubule-associated protein 1A is the fibroblast HMW MAP undergoing mitogen-stimulated serine phosphorylation. Erickson, A.K., Ray, L.B., Sturgill, T.W. Biochem. Biophys. Res. Commun. (1990) [Pubmed]
  8. The functional cooperation of MAP1A heavy chain and light chain 2 in the binding of microtubules. Chien, C.L., Lu, K.S., Lin, Y.S., Hsieh, C.J., Hirokawa, N. Exp. Cell Res. (2005) [Pubmed]
  9. Differential distribution of MAP1A isoforms in the adult mouse barrel cortex and comparison with the serotonin 5-HT2A receptor. Touri, F., Welker, E., Riederer, B.M. J. Chem. Neuroanat. (2004) [Pubmed]
  10. Identification of high molecular weight microtubule-associated proteins in anterior pituitary tissue and cells using taxol-dependent purification combined with microtubule-associated protein specific antibodies. Bloom, G.S., Luca, F.C., Vallee, R.B. Biochemistry (1985) [Pubmed]
 
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