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Gene Review

Chpt1  -  choline phosphotransferase 1

Mus musculus

Synonyms: Cholinephosphotransferase 1, Cpt1, Diabetic nephropathy-associated gene transcript 1, Diacylglycerol cholinephosphotransferase 1, Dn4, ...
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Disease relevance of Chpt1


High impact information on Chpt1


Chemical compound and disease context of Chpt1


Biological context of Chpt1

  • The time-dependent accumulation of IT was primarily due to axonal transport, while that of CPT was largely a result of increased enzyme activity in local Schwann cells [6].

Anatomical context of Chpt1


Associations of Chpt1 with chemical compounds


Analytical, diagnostic and therapeutic context of Chpt1

  • Evidence came from double ligation studies, where a proximal ligature, acting to restrict orthograde axonal transport, reduced accumulation in a distal ligature by 80% for IT, but only 28% for CPT [6].


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