Gene Review:
CHPT1 - choline phosphotransferase 1
Homo sapiens
Synonyms:
AAPT1-like protein, CPT, CPT1, Cholinephosphotransferase 1, Diacylglycerol cholinephosphotransferase 1, ...
- Modulation of cholinephosphotransferase activity in breast cancer cell lines by Ro5-4864, a peripheral benzodiazepine receptor agonist. Akech, J., Roy, S.S., Das, S.K. Biochem. Biophys. Res. Commun. (2005)
- C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Thupari, J.N., Landree, L.E., Ronnett, G.V., Kuhajda, F.P. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Irinotecan dosing: does the CPT in CPT-11 stand for "Can't Predict Toxicity"? Ratain, M.J. J. Clin. Oncol. (2002)
- Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance. Kanzawa, F., Sugimoto, Y., Minato, K., Kasahara, K., Bungo, M., Nakagawa, K., Fujiwara, Y., Liu, L.F., Saijo, N. Cancer Res. (1990)
- Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells. Miquel, K., Pradines, A., Tercé, F., Selmi, S., Favre, G. J. Biol. Chem. (1998)
- CPT: a cure for fiscal agnosia. Rosenbaum, H.E., Segerson, J. Neurology (1979)
- Effects of nicotine nasal spray on cognitive function in schizophrenia. Smith, R.C., Warner-Cohen, J., Matute, M., Butler, E., Kelly, E., Vaidhyanathaswamy, S., Khan, A. Neuropsychopharmacology (2006)
- Source analysis of the N2 in a cued Go/NoGo task. Bekker, E.M., Kenemans, J.L., Verbaten, M.N. Brain research. Cognitive brain research. (2005)
- Slowed reaction time in asymptomatic HIV-positive patients. Karlsen, N.R., Reinvang, I., Frøland, S.S. Acta neurologica Scandinavica. (1992)
- Commentary. Health and behavior CPT codes: an opportunity to revolutionize reimbursement in pediatric psychology. Noll, R.B., Fischer, S. Journal of pediatric psychology. (2004)
- Molecular basis of hepatic carnitine palmitoyltransferase I deficiency. IJlst, L., Mandel, H., Oostheim, W., Ruiter, J.P., Gutman, A., Wanders, R.J. J. Clin. Invest. (1998)
- Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials. Tanizawa, A., Fujimori, A., Fujimori, Y., Pommier, Y. J. Natl. Cancer Inst. (1994)
- Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. Folmes, C.D., Lopaschuk, G.D. Cardiovasc. Res. (2007)
- Immunosuppressive activity of capsaicinoids: capsiate derived from sweet peppers inhibits NF-kappaB activation and is a potent antiinflammatory compound in vivo. Sancho, R., Lucena, C., Macho, A., Calzado, M.A., Blanco-Molina, M., Minassi, A., Appendino, G., Muñoz, E. Eur. J. Immunol. (2002)
- Guanfacine treatment of cognitive impairment in schizophrenia. Friedman, J.I., Adler, D.N., Temporini, H.D., Kemether, E., Harvey, P.D., White, L., Parrella, M., Davis, K.L. Neuropsychopharmacology (2001)
- Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training. Schenk, S., Horowitz, J.F. Am. J. Physiol. Endocrinol. Metab. (2006)
- Lipid oxidation is reduced in obese human skeletal muscle. Kim, J.Y., Hickner, R.C., Cortright, R.L., Dohm, G.L., Houmard, J.A. Am. J. Physiol. Endocrinol. Metab. (2000)
- Cloning, genomic organization, and characterization of a human cholinephosphotransferase. Henneberry, A.L., Wistow, G., McMaster, C.R. J. Biol. Chem. (2000)
- ACE inhibition attenuates sympathetic coronary vasoconstriction in patients with coronary artery disease. Perondi, R., Saino, A., Tio, R.A., Pomidossi, G., Gregorini, L., Alessio, P., Morganti, A., Zanchetti, A., Mancia, G. Circulation (1992)
- Selective accumulation of cytosol CDP-choline as an isolated erythrocyte defect in chronic hemolysis. Paglia, D.E., Valentine, W.N., Nakatani, M., Rauth, B.J. Proc. Natl. Acad. Sci. U.S.A. (1983)
- Differential expression of cholinephosphotransferase in normal and cancerous human mammary epithelial cells. Ghosh, A., Akech, J., Mukherjee, S., Das, S.K. Biochem. Biophys. Res. Commun. (2002)
- Phospholipid-metabolizing enzymes in Alzheimer's disease: increased lysophospholipid acyltransferase activity and decreased phospholipase A2 activity. Ross, B.M., Moszczynska, A., Erlich, J., Kish, S.J. J. Neurochem. (1998)
- Signal transduction in vascular smooth muscle: diacylglycerol second messengers and PKC action. Lee, M.W., Severson, D.L. Am. J. Physiol. (1994)
- Sympathetic stimulation overrides flow-mediated endothelium-dependent epicardial coronary vasodilation in transplant patients. Aptecar, E., Dupouy, P., Benvenuti, C., Mazzucotelli, J.P., Teiger, E., Geschwind, H., Castaigne, A., Loisance, D., Dubois-Rande, J.L. Circulation (1996)
- Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene. Britton, C.H., Schultz, R.A., Zhang, B., Esser, V., Foster, D.W., McGarry, J.D. Proc. Natl. Acad. Sci. U.S.A. (1995)
- p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine. Furuta, T., Hayward, R.L., Meng, L.H., Takemura, H., Aune, G.J., Bonner, W.M., Aladjem, M.I., Kohn, K.W., Pommier, Y. Oncogene (2006)
- Novel mutations associated with carnitine palmitoyltransferase II deficiency. Taggart, R.T., Smail, D., Apolito, C., Vladutiu, G.D. Hum. Mutat. (1999)
- Abnormalities in the distributed network of sustained attention predict neuroleptic treatment response in schizophrenia. Cohen, R.M., Nordahl, T.E., Semple, W.E., Andreason, P., Pickar, D. Neuropsychopharmacology (1998)