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Gene Review

Apoc3  -  apolipoprotein C-III

Rattus norvegicus

Synonyms: Apo-CIII, ApoC-III, Apolipoprotein C-III, Apolipoprotein C3, apo-CIII
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Disease relevance of Apoc3


High impact information on Apoc3


Biological context of Apoc3


Anatomical context of Apoc3


Associations of Apoc3 with chemical compounds


Other interactions of Apoc3


  1. Isotretinoin and fenofibrate induce adiposity with distinct effect on metabolic profile in a rat model of the insulin resistance syndrome. Sedova, L., Seda, O., Krenova, D., Kren, V., Kazdova, L. Int. J. Obes. Relat. Metab. Disord. (2004) [Pubmed]
  2. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Sladek, F.M., Zhong, W.M., Lai, E., Darnell, J.E. Genes Dev. (1990) [Pubmed]
  3. Glucose regulates the expression of the farnesoid X receptor in liver. Duran-Sandoval, D., Mautino, G., Martin, G., Percevault, F., Barbier, O., Fruchart, J.C., Kuipers, F., Staels, B. Diabetes (2004) [Pubmed]
  4. Apolipoprotein B messenger RNA editing in the rat liver. Modulation by fasting and refeeding a high carbohydrate diet. Baum, C.L., Teng, B.B., Davidson, N.O. J. Biol. Chem. (1990) [Pubmed]
  5. The hypochylomicronemic effect of beta,beta'-methyl-substituted hexadecanedioic acid (MEDICA 16) is mediated by a decrease in apolipoprotein C-III. Frenkel, B., Mayorek, N., Hertz, R., Bar-Tana, J. J. Biol. Chem. (1988) [Pubmed]
  6. Biosynthesis of apolipoprotein C-III in rat liver and small intestinal mucosa. Blaufuss, M.C., Gordon, J.I., Schonfeld, G., Strauss, A.W., Alpers, D.H. J. Biol. Chem. (1984) [Pubmed]
  7. Genes of the immune system cosegregate with the age at onset of diabetes in the BB/OK rat. Klöting, I., Kovacs, P. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  8. Transcriptional regulation of the apolipoprotein A-IV gene involves synergism between a proximal orphan receptor response element and a distant enhancer located in the upstream promoter region of the apolipoprotein C-III gene. Ktistaki, E., Lacorte, J.M., Katrakili, N., Zannis, V.I., Talianidis, I. Nucleic Acids Res. (1994) [Pubmed]
  9. Insulin in UW solution exacerbates hepatic ischemia / reperfusion injury by energy depletion through the IRS-2 / SREBP-1c pathway. Li, X.L., Man, K., Ng, K.T., Lee, T.K., Lo, C.M., Fan, S.T. Liver Transpl. (2004) [Pubmed]
  10. Effects of apolipoproteins C on oxidative phosphorylation in rat liver mitochondria. Panin, L.E., Shalbueva, N.I., Polyakov, L.M. Bull. Exp. Biol. Med. (2000) [Pubmed]
  11. Hypolipidemic effect of peroxisome proliferators. Transcriptional suppression of apolipoprotein C-III. Hertz, R., Bishara-Shieban, J., Bar-Tana, J. Ann. N. Y. Acad. Sci. (1996) [Pubmed]
  12. Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the Zucker diabetic fatty rat. Dana, S.L., Hoener, P.A., Bilakovics, J.M., Crombie, D.L., Ogilvie, K.M., Kauffman, R.F., Mukherjee, R., Paterniti, J.R. Metab. Clin. Exp. (2001) [Pubmed]
  13. The effect of beta,beta'-tetramethylhexadecanedioic acid (MEDICA 16) on plasma very-low-density lipoprotein metabolism in rats: role of apolipoprotein C-III. Frenkel, B., Bishara-Shieban, J., Bar-Tana, J. Biochem. J. (1994) [Pubmed]
  14. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors reduce serum triglyceride levels through modulation of apolipoprotein C-III and lipoprotein lipase. Schoonjans, K., Peinado-Onsurbe, J., Fruchart, J.C., Tailleux, A., Fiévet, C., Auwerx, J. FEBS Lett. (1999) [Pubmed]
  15. Tesaglitazar, a dual PPAR{alpha}/{gamma} agonist, ameliorates glucose and lipid intolerance in obese Zucker rats. Oakes, N.D., Thalén, P., Hultstrand, T., Jacinto, S., Camejo, G., Wallin, B., Ljung, B. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2005) [Pubmed]
  16. A comparison of the surface activities of rat plasma apolipoproteins C-II, C-III-0, C-III-3. Krebs, K.E., Phillips, M.C., Sparks, C.E. Biochim. Biophys. Acta (1983) [Pubmed]
  17. Peroxisome proliferator-activated receptor-alpha expression in rat liver during postnatal development. Panadero, M., Herrera, E., Bocos, C. Biochimie (2000) [Pubmed]
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