Gene Review:
Gpx1 - glutathione peroxidase 1
Rattus norvegicus
Synonyms:
Cellular glutathione peroxidase, GPx-1, GSHPx, GSHPx-1, Glutathione peroxidase 1
Abílio,
Silva,
Carvalho,
Grassl,
Calzavara,
Registro,
D'Almeida,
Ribeiro,
Frussa-Filho,
Fujimura,
Sumita,
Aimono,
Masuda,
Shichinohe,
Narimatsu,
Namiki,
DeKosky,
Abrahamson,
Taffe,
Dixon,
Kochanek,
Ikonomovic,
Eraković,
Zupan,
Varljen,
Radosević,
Simonić,
Bardak,
Ozertürk,
Ozgüner,
Durmuş,
Delibaş,
Vaziri,
Lin,
Farmand,
Sindhu,
Drew,
Farquharson,
Arthur,
Morrice,
Duthie,
Gilks,
Price,
Wright,
Churg,
- Superoxide dismutase, catalase, glutathione peroxidase and NADPH oxidase in lead-induced hypertension. Vaziri, N.D., Lin, C.Y., Farmand, F., Sindhu, R.K. Kidney Int. (2003)
- Lipid peroxidation and free radical scavengers in thyroid dysfunction in the rat: a possible mechanism of injury to heart and skeletal muscle in hyperthyroidism. Asayama, K., Dobashi, K., Hayashibe, H., Megata, Y., Kato, K. Endocrinology (1987)
- Over-expression of antioxidant enzymes protects cultured hippocampal and cortical neurons from necrotic insults. Wang, H., Cheng, E., Brooke, S., Chang, P., Sapolsky, R. J. Neurochem. (2003)
- Neuronal transfer of the human Cu/Zn superoxide dismutase gene increases the resistance of dopaminergic neurons to 6-hydroxydopamine. Barkats, M., Millecamps, S., Bilang-Bleuel, A., Mallet, J. J. Neurochem. (2002)
- Effects of post-injury hypothermia and nerve growth factor infusion on antioxidant enzyme activity in the rat: implications for clinical therapies. DeKosky, S.T., Abrahamson, E.E., Taffe, K.M., Dixon, C.E., Kochanek, P.M., Ikonomovic, M.D. J. Neurochem. (2004)
- Important role of striatal catalase in aging- and reserpine-induced oral dyskinesia. Abílio, V.C., Silva, R.H., Carvalho, R.C., Grassl, C., Calzavara, M.B., Registro, S., D'Almeida, V., Ribeiro, R.d.e. .A., Frussa-Filho, R. Neuropharmacology (2004)
- Sleep deprivation decreases superoxide dismutase activity in rat hippocampus and brainstem. Ramanathan, L., Gulyani, S., Nienhuis, R., Siegel, J.M. Neuroreport (2002)
- Electroconvulsive shock in rats: changes in superoxide dismutase and glutathione peroxidase activity. Eraković, V., Zupan, G., Varljen, J., Radosević, S., Simonić, A. Brain Res. Mol. Brain Res. (2000)
- Effects of crocetin on the hepatotoxicity and hepatic DNA binding of aflatoxin B1 in rats. Wang, C.J., Shiow, S.J., Lin, J.K. Carcinogenesis (1991)
- Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3' untranslated region. Berry, M.J., Banu, L., Chen, Y.Y., Mandel, S.J., Kieffer, J.D., Harney, J.W., Larsen, P.R. Nature (1991)
- Defective microbicidal activity in glutathione peroxidase-deficient neutrophils of selenium-deficient rats. Serfass, R.E., Ganther, H.E. Nature (1975)
- Pertussis toxin treatment alters manganese superoxide dismutase activity in lung. Evidence for lung oxygen toxicity in air-breathing rats. Clerch, L.B., Neithardt, G., Spencer, U., Melendez, J.A., Massaro, G.D., Massaro, D. J. Clin. Invest. (1994)
- Time course and mechanism of oxidative stress and tissue damage in rat liver subjected to in vivo ischemia-reperfusion. González-Flecha, B., Cutrin, J.C., Boveris, A. J. Clin. Invest. (1993)
- Differential effect of dietary methionine on the biopotency of selenomethionine and selenite in cancer chemoprevention. Ip, C. J. Natl. Cancer Inst. (1988)
- Cardiac and renal antioxidant enzymes and effects of tempol in hyperthyroid rats. Moreno, J.M., Rodríguez Gómez, I., Wangensteen, R., Osuna, A., Bueno, P., Vargas, F. Am. J. Physiol. Endocrinol. Metab. (2005)
- Superoxide dismutase, glutathione peroxidase activities and the hydroperoxide concentration are modified in the hippocampus of epileptic rats. Bellissimo, M.I., Amado, D., Abdalla, D.S., Ferreira, E.C., Cavalheiro, E.A., Naffah-Mazzacoratti, M.G. Epilepsy Res. (2001)
- Poor correlation between oxygen toxicity and activity of glutathione peroxidase. Ospital, J.J., Kasuyama, R.S., Tierney, D.F. Exp. Lung Res. (1983)
- Effect of melatonin against oxidative stress in ultraviolet-B exposed rat lens. Bardak, Y., Ozertürk, Y., Ozgüner, F., Durmuş, M., Delibaş, N. Curr. Eye Res. (2000)
- Gene expression of antioxidant enzymes in experimental diabetic neuropathy. Kishi, Y., Nickander, K.K., Schmelzer, J.D., Low, P.A. J. Peripher. Nerv. Syst. (2000)
- Nonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissues. Sun, X., Li, X., Moriarty, P.M., Henics, T., LaDuca, J.P., Maquat, L.E. Mol. Biol. Cell (2001)
- Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species. Tiedge, M., Lortz, S., Munday, R., Lenzen, S. Diabetes (1998)
- Effect of free radical scavengers on diaphragmatic contractility in septic peritonitis. Fujimura, N., Sumita, S., Aimono, M., Masuda, Y., Shichinohe, Y., Narimatsu, E., Namiki, A. Am. J. Respir. Crit. Care Med. (2000)
- Antioxidant S-allylcysteine prevents gentamicin-induced oxidative stress and renal damage. Maldonado, P.D., Barrera, D., Rivero, I., Mata, R., Medina-Campos, O.N., Hernández-Pando, R., Pedraza-Chaverrí, J. Free Radic. Biol. Med. (2003)
- Pro-oxidant activity of aluminum in the rat hippocampus: gene expression of antioxidant enzymes after melatonin administration. Gómez, M., Esparza, J.L., Nogués, M.R., Giralt, M., Cabré, M., Domingo, J.L. Free Radic. Biol. Med. (2005)
- Novel sites of cytosolic glutathione peroxidase expression in colon. Drew, J.E., Farquharson, A.J., Arthur, J.R., Morrice, P.C., Duthie, G.G. FEBS Lett. (2005)
- Modulation of azaserine-induced pancreatic foci by phenolic antioxidants in rats. Roebuck, B.D., MacMillan, D.L., Bush, D.M., Kensler, T.W. J. Natl. Cancer Inst. (1984)
- Antioxidant gene expression in rat lung after exposure to cigarette smoke. Gilks, C.B., Price, K., Wright, J.L., Churg, A. Am. J. Pathol. (1998)
- Tolerance of rats to hyperoxia. Lung antioxidant enzyme gene expression. Clerch, L.B., Massaro, D. J. Clin. Invest. (1993)
- Effects of iron loading on free radical scavenging enzymes and lipid peroxidation in rat liver. Fletcher, L.M., Roberts, F.D., Irving, M.G., Powell, L.W., Halliday, J.W. Gastroenterology (1989)
- Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats. Hill, M.F., Singal, P.K. Am. J. Pathol. (1996)
- Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro. Lampe, M.A., Kammerer, R.C. Carcinogenesis (1987)
- An investigation into the effect of sulfonylurea glyburide on glutathione peroxidase activity in streptozotocin-induced diabetic rat muscle tissue. Kiliç, N., Malhatun, E., Elmali, E., Altan, N. Gen. Pharmacol. (1998)
- Regional distribution of glutathione reductase in the adult rat brain. Brannan, T.S., Maker, H.S., Raes, I., Weiss, C. Brain Res. (1980)
- Increased spontaneous chemiluminescence from liver homogenates and isolated hepatocytes upon inhibition of O2- and H2O2 utilization. Turrens, J.F., Giulivi, C., Boveris, A. Journal of free radicals in biology & medicine. (1986)
- Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, protects against gastric ischemia-reperfusion damage in rats: role of oxygen free radicals generation. Villegas, I., Martín, A.R., Toma, W., de la Lastra, C.A. Eur. J. Pharmacol. (2004)
- Dietary selenium intake controls rat plasma selenoprotein P concentration. Yang, J.G., Hill, K.E., Burk, R.F. J. Nutr. (1989)
- Testis glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase activities in aminoguanidine-treated diabetic rats. Unlüçerçi, Y., Bekpinar, S., Koçak, H. Arch. Biochem. Biophys. (2000)
- Involvement of superoxide dismutase and glutathione peroxidase in attenuation of radiation-induced hyperthermia by interleukin-1 alpha in rats. Kandasamy, S.B., Kumar, K.S., Harris, A.H. Brain Res. (1993)
- Protective effect of SnCl2 on K2Cr2O7-induced nephrotoxicity in rats: the indispensability of HO-1 preinduction and lack of association with some antioxidant enzymes. Barrera, D., Maldonado, P.D., Medina-Campos, O.N., Hernández-Pando, R., Ibarra-Rubio, M.E., Pedraza-Chaverrí, J. Life Sci. (2003)
- Melatonin stimulates the activity of protective antioxidative enzymes in myocardial cells of rats in the course of doxorubicin intoxication. Dziegiel, P., Murawska-Ciałowicz, E., Jethon, Z., Januszewska, L., Podhorska-Okołów, M., Surowiak, P., Zawadzki, M., Rabczyński, J., Zabel, M. J. Pineal Res. (2003)
- Antioxidant enzymes in ciprofibrate-induced oxidative stress. Dhaunsi, G.S., Singh, I., Orak, J.K., Singh, A.K. Carcinogenesis (1994)
- Inhibition of bleomycin-induced pulmonary fibrosis by lipopolysaccharide. Phan, S.H., Fantone, J.C. Lab. Invest. (1984)