Gene Review:
Stat5b - signal transducer and activator of...
Rattus norvegicus
Synonyms:
Signal transducer and activator of transcription 5B
Guren,
Abrahamsen,
Thoresen,
Babaie,
Berg,
Christoffersen,
Helander,
Gustafsson,
Mode,
Guren,
Ødegård,
Abrahamsen,
Thoresen,
Susa,
Andersson,
Østby,
Christoffersen,
- Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements. Ripperger, J.A., Fritz, S., Richter, K., Hocke, G.M., Lottspeich, F., Fey, G.H. J. Biol. Chem. (1995)
- Characterization of distinct Stat5b binding sites that mediate growth hormone-stimulated IGF-I gene transcription. Chia, D.J., Ono, M., Woelfle, J., Schlesinger-Massart, M., Jiang, H., Rotwein, P. J. Biol. Chem. (2006)
- Transcriptional inhibition by Stat5. Differential activities at growth-related versus differentiation-specific promoters. Luo, G., Yu-Lee, L. J. Biol. Chem. (1997)
- Acute control of insulin-like growth factor-I gene transcription by growth hormone through Stat5b. Woelfle, J., Billiard, J., Rotwein, P. J. Biol. Chem. (2003)
- Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation. Woelfle, J., Chia, D.J., Rotwein, P. J. Biol. Chem. (2003)
- EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes. Guren, T.K., Ødegård, J., Abrahamsen, H., Thoresen, G.H., Susa, M., Andersson, Y., Østby, E., Christoffersen, T. J. Cell. Physiol. (2003)
- PRL-induced ERalpha gene expression is mediated by Janus kinase 2 (Jak2) while signal transducer and activator of transcription 5b (Stat5b) phosphorylation involves Jak2 and a second tyrosine kinase. Frasor, J., Barkai, U., Zhong, L., Fazleabas, A.T., Gibori, G. Mol. Endocrinol. (2001)
- Lactogenic hormone-inducible phosphorylation and gamma-activated site-binding activities of Stat5b in primary rat Leydig cells and MA-10 mouse Leydig tumor cells. Kanzaki, M., Morris, P.L. Endocrinology (1998)
- PRL signal transduction in the epithelial compartment of rat prostate maintained as long-term organ cultures in vitro. Ahonen, T.J., Härkönen, P.L., Rui, H., Nevalainen, M.T. Endocrinology (2002)
- EGF-induced activation of Stat1, Stat3, and Stat5b is unrelated to the stimulation of DNA synthesis in cultured hepatocytes. Guren, T.K., Abrahamsen, H., Thoresen, G.H., Babaie, E., Berg, T., Christoffersen, T. Biochem. Biophys. Res. Commun. (1999)
- Effect of erythropoietin on Leydig cell is associated with the activation of Stat5 pathway. Yamazaki, T., Kanzaki, M., Kamidono, S., Fujisawa, M. Mol. Cell. Endocrinol. (2004)
- Possible involvement of truncated signal transducer and activator of transcription-5 in the GH pattern-dependent regulation of CYP2C12 gene expression in rat liver. Helander, H., Gustafsson, J.A., Mode, A. Mol. Endocrinol. (2002)