Gene Review:
SH3KBP1 - SH3-domain kinase binding protein 1
Homo sapiens
Synonyms:
CD2-binding protein 3, CD2BP3, CIN85, Cbl-interacting protein of 85 kDa, GIG10, ...
- Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces. Liang, Y., Kurakin, A., Roizman, B. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Overexpression of CIN85 suppresses the growth of herpes simplex virus in HeLa cells. Narita, T., Ando, A., Mikami, Y., Taniyama, T. Exp. Cell Res. (2005)
- Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Soubeyran, P., Kowanetz, K., Szymkiewicz, I., Langdon, W.Y., Dikic, I. Nature (2002)
- The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. Petrelli, A., Gilestro, G.F., Lanzardo, S., Comoglio, P.M., Migone, N., Giordano, S. Nature (2002)
- Assignment of SH3KBP1 to human chromosome band Xp22.1-->p21.3 by in situ hybridization. Narita, T., Amano, F., Yoshizaki, K., Nishimoto, N., Nishimura, T., Tajima, T., Namiki, H., Taniyama, T. Cytogenet. Cell Genet. (2001)
- CIN85 associates with TNF receptor 1 via Src and modulates TNF-alpha-induced apoptosis. Narita, T., Nishimura, T., Yoshizaki, K., Taniyama, T. Exp. Cell Res. (2005)
- Phosphorylation of the proline-rich domain of Xp95 modulates Xp95 interaction with partner proteins. Dejournett, R.E., Kobayashi, R., Pan, S., Wu, C., Etkin, L.D., Clark, R.B., B??gler, O., Kuang, J. Biochem. J. (2007)
- Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes. Watanabe, S., Take, H., Takeda, K., Yu, Z.X., Iwata, N., Kajigaya, S. Biochem. Biophys. Res. Commun. (2000)
- Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors. Haglund, K., Shimokawa, N., Szymkiewicz, I., Dikic, I. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl. Take, H., Watanabe, S., Takeda, K., Yu, Z.X., Iwata, N., Kajigaya, S. Biochem. Biophys. Res. Commun. (2000)
- Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors. Kowanetz, K., Szymkiewicz, I., Haglund, K., Kowanetz, M., Husnjak, K., Taylor, J.D., Soubeyran, P., Engstrom, U., Ladbury, J.E., Dikic, I. J. Biol. Chem. (2003)
- Isolation of differentially expressed sequence tags from steroid-responsive cells using mRNA differential display. Chapman, M.S., Qu, N., Pascoe, S., Chen, W.X., Apostol, C., Gordon, D., Miesfeld, R.L. Mol. Cell. Endocrinol. (1995)
- The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway. Peruzzi, G., Molfetta, R., Gasparrini, F., Vian, L., Morrone, S., Piccoli, M., Frati, L., Santoni, A., Paolini, R. J. Immunol. (2007)
- CD2BP3, CIN85 and the structurally related adaptor protein CMS bind to the same CD2 cytoplasmic segment, but elicit divergent functional activities. Tibaldi, E.V., Reinherz, E.L. Int. Immunol. (2003)
- CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors. Kowanetz, K., Husnjak, K., Höller, D., Kowanetz, M., Soubeyran, P., Hirsch, D., Schmidt, M.H., Pavelic, K., De Camilli, P., Randazzo, P.A., Dikic, I. Mol. Biol. Cell (2004)
- Cbl promotes clustering of endocytic adaptor proteins. Jozic, D., Cárdenes, N., Deribe, Y.L., Moncalián, G., Hoeller, D., Groemping, Y., Dikic, I., Rittinger, K., Bravo, J. Nature structural & molecular biology. (2005)
- Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85. Hutchings, N.J., Clarkson, N., Chalkley, R., Barclay, A.N., Brown, M.H. J. Biol. Chem. (2003)
- Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening. Kurakin, A.V., Wu, S., Bredesen, D.E. J. Biol. Chem. (2003)
- CIN85 is localized at synapses and forms a complex with S-SCAM via dendrin. Kawata, A., Iida, J., Ikeda, M., Sato, Y., Mori, H., Kansaku, A., Sumita, K., Fujiwara, N., Rokukawa, C., Hamano, M., Hirabayashi, S., Hata, Y. J. Biochem. (2006)