Gene Review:
HADHB - hydroxyacyl-CoA dehydrogenase/3-ketoacyl...
Homo sapiens
Synonyms:
ECHB, MSTP029, MTPB, TP-BETA, TP-beta, ...
- Genomic and mutational analysis of the mitochondrial trifunctional protein beta-subunit (HADHB) gene in patients with trifunctional protein deficiency. Orii, K.E., Aoyama, T., Wakui, K., Fukushima, Y., Miyajima, H., Yamaguchi, S., Orii, T., Kondo, N., Hashimoto, T. Hum. Mol. Genet. (1997)
- Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells. Coyle, A.T., Kinsella, B.T. Biochem. Pharmacol. (2006)
- ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein {beta}-subunit. Kao, H.J., Cheng, C.F., Chen, Y.H., Hung, S.I., Huang, C.C., Millington, D., Kikuchi, T., Wu, J.Y., Chen, Y.T. Hum. Mol. Genet. (2006)
- The intracellular trafficking of the G protein-coupled receptor TPbeta depends on a direct interaction with Rab11. Hamelin, E., Thériault, C., Laroche, G., Parent, J.L. J. Biol. Chem. (2005)
- Involvement of actin in agonist-induced endocytosis of the G protein-coupled receptor for thromboxane A2: overcoming of actin disruption by arrestin-3 but not arrestin-2. Laroche, G., Rochdi, M.D., Laporte, S.A., Parent, J.L. J. Biol. Chem. (2005)
- Genes for the human mitochondrial trifunctional protein alpha- and beta-subunits are divergently transcribed from a common promoter region. Orii, K.E., Orii, K.O., Souri, M., Orii, T., Kondo, N., Hashimoto, T., Aoyama, T. J. Biol. Chem. (1999)
- Fluorescence in situ hybridization mapping of the alpha and beta subunits (HADHA and HADHB) of human mitochondrial fatty acid beta-oxidation multienzyme complex to 2p23 and their evolution. Aoyama, T., Wakui, K., Orii, K.E., Hashimoto, T., Fukushima, Y. Cytogenet. Cell Genet. (1997)
- The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for nitric oxide-mediated desensitization. Independent modulation of Tp alpha signaling by nitric oxide and prostacyclin. Reid, H.M., Kinsella, B.T. J. Biol. Chem. (2003)
- Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors. Paul, B.Z., Jin, J., Kunapuli, S.P. J. Biol. Chem. (1999)
- HADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA and differentially modulate renin expression. Adams, D.J., Beveridge, D.J., van der Weyden, L., Mangs, H., Leedman, P.J., Morris, B.J. J. Biol. Chem. (2003)
- Nm23-H2 interacts with a G protein-coupled receptor to regulate its endocytosis through an Rac1-dependent mechanism. Rochdi, M.D., Laroche, G., Dupré, E., Giguère, P., Lebel, A., Watier, V., Hamelin, E., Lépine, M.C., Dupuis, G., Parent, J.L. J. Biol. Chem. (2004)
- Differential signaling by the thromboxane receptor isoforms via the novel GTP-binding protein, Gh. Vezza, R., Habib, A., FitzGerald, G.A. J. Biol. Chem. (1999)
- Rapid, agonist-dependent phosphorylation in vivo of human thromboxane receptor isoforms. Minimal involvement of protein kinase C. Habib, A., Vezza, R., Créminon, C., Maclouf, J., FitzGerald, G.A. J. Biol. Chem. (1997)
- Effect of the statin atorvastatin on intracellular signalling by the prostacyclin receptor in vitro and in vivo. O'Meara, S.J., Kinsella, B.T. Br. J. Pharmacol. (2004)
- ARF6 activation by Galpha(q) signaling: Galpha(q) forms molecular complexes with ARNO and ARF6. Gigu??re, P., Rochdi, M.D., Laroche, G., Dupr??, E., Whorton, M.R., Sunahara, R.K., Claing, A., Dupuis, G., Parent, J.L. Cell. Signal. (2006)
- Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration. Ashton, A.W., Ware, J.A. Circ. Res. (2004)
- Galphaq-coupled receptor internalization specifically induced by Galphaq signaling. Regulation by EBP50. Rochdi, M.D., Parent, J.L. J. Biol. Chem. (2003)
- Role of the differentially spliced carboxyl terminus in thromboxane A2 receptor trafficking: identification of a distinct motif for tonic internalization. Parent, J.L., Labrecque, P., Driss Rochdi, M., Benovic, J.L. J. Biol. Chem. (2001)
- Pharmacological and molecular biological (RT-PCR) characterization of functional TP prostanoid receptors in immortalized human non-pigmented ciliary epithelial cells. Sharif, N.A., Senchyna, M., Xu, S.X. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. (2002)