Gene Review:
S6k - RPS6-p70-protein kinase
Drosophila melanogaster
Synonyms:
10539, 7084, CG10539, DS6K, Dmel\CG10539, ...
- Increased Rheb-TOR signaling enhances sensitivity of the whole organism to oxidative stress. Patel, P.H., Tamanoi, F. J. Cell. Sci. (2006)
- Drosophila S6 kinase: a regulator of cell size. Montagne, J., Stewart, M.J., Stocker, H., Hafen, E., Kozma, S.C., Thomas, G. Science (1999)
- The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Reiling, J.H., Hafen, E. Genes Dev. (2004)
- Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Stocker, H., Radimerski, T., Schindelholz, B., Wittwer, F., Belawat, P., Daram, P., Breuer, S., Thomas, G., Hafen, E. Nat. Cell Biol. (2003)
- Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B. Lizcano, J.M., Alrubaie, S., Kieloch, A., Deak, M., Leevers, S.J., Alessi, D.R. Biochem. J. (2003)
- A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene. Watson, K.L., Chou, M.M., Blenis, J., Gelbart, W.M., Erikson, R.L. Proc. Natl. Acad. Sci. U.S.A. (1996)
- The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity. Stewart, M.J., Berry, C.O., Zilberman, F., Thomas, G., Kozma, S.C. Proc. Natl. Acad. Sci. U.S.A. (1996)
- PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids. Goberdhan, D.C., Meredith, D., Boyd, C.A., Wilson, C. Development (2005)
- TOR action in mammalian cells and in Caenorhabditis elegans. Long, X., Müller, F., Avruch, J. Curr. Top. Microbiol. Immunol. (2004)
- Identification of the S6 kinase activity stimulated in quiescent brine shrimp embryos upon entry to preemergence development as p70 ribosomal protein S6 kinase: isolation of Artemia franciscana p70S6k cDNA. Santiago, J., Sturgill, T.W. Biochem. Cell Biol. (2001)
- PDK1 regulates growth through Akt and S6K in Drosophila. Rintelen, F., Stocker, H., Thomas, G., Hafen, E. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Gao, X., Zhang, Y., Arrazola, P., Hino, O., Kobayashi, T., Yeung, R.S., Ru, B., Pan, D. Nat. Cell Biol. (2002)