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HMOX1  -  heme oxygenase (decycling) 1

Gallus gallus

 
 
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Disease relevance of HMOX1

  • Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases [1].
  • Activation of cSrc and expression of the HO-1 gene product are each induced under conditions of hypoxia [2].
 

High impact information on HMOX1

 

Biological context of HMOX1

 

Anatomical context of HMOX1

 

Associations of HMOX1 with chemical compounds

 

Other interactions of HMOX1

 

Analytical, diagnostic and therapeutic context of HMOX1

References

  1. Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases. Elbirt, K.K., Whitmarsh, A.J., Davis, R.J., Bonkovsky, H.L. J. Biol. Chem. (1998) [Pubmed]
  2. Chimeric constructs containing the SH4/Unique domains of cYes can restrict the ability of Src(527F) to upregulate heme oxygenase-1 expression efficiently. Hoey, J.G., Summy, J., Flynn, D.C. Cell. Signal. (2000) [Pubmed]
  3. Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells. Cable, E.E., Pepe, J.A., Karamitsios, N.C., Lambrecht, R.W., Bonkovsky, H.L. J. Clin. Invest. (1994) [Pubmed]
  4. Hormonal regulation of heme oxygenase induction in avian hepatocyte culture. Sardana, M.K., Sassa, S., Kappas, A. Biochem. Pharmacol. (1985) [Pubmed]
  5. Mapping of the chick heme oxygenase-1 proximal promoter for responsiveness to metalloporphyrins. Shan, Y., Pepe, J., Lambrecht, R.W., Bonkovsky, H.L. Arch. Biochem. Biophys. (2002) [Pubmed]
  6. Molecular cloning, characterization, and expression of the chicken heme oxygenase-1 gene in transfected primary cultures of chick embryo liver cells. Lu, T.H., Lambrecht, R.W., Pepe, J., Shan, Y., Kim, T., Bonkovsky, H.L. Gene (1998) [Pubmed]
  7. Mechanism of synergistic induction of hepatic heme oxygenase by glutethimide and iron: studies in cultured chick embryo liver cells. Cable, E., Greene, Y., Healey, J., Evans, C.O., Bonkovsky, H. Biochem. Biophys. Res. Commun. (1990) [Pubmed]
  8. Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme. Srivastava, K.K., Cable, E.E., Donohue, S.E., Bonkovsky, H.L. Eur. J. Biochem. (1993) [Pubmed]
  9. Effects of phenylarsine oxide on expression of heme oxygenase-1 reporter constructs in transiently transfected cultures of chick embryo liver cells. Shan, Y., Lambrecht, R.W., Hong Lu, T., Bonkovsky, H.L. Arch. Biochem. Biophys. (1999) [Pubmed]
  10. Altered regulation of hepatic heme metabolism in cadmium exposed chick embryo. Prasad, A.R., Datta, K. Biochem. Int. (1984) [Pubmed]
 
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