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Gene Review

OSTEO  -  Osteochondrosis score

Sus scrofa

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Disease relevance of OSTEO


High impact information on OSTEO


Chemical compound and disease context of OSTEO


Biological context of OSTEO


Anatomical context of OSTEO


Associations of OSTEO with chemical compounds

  • Histological examination of lung, stomach, kidney, liver and heart indicated no abnormalities, but focal microscopic lesions consistent with osteochondrosis were found in pigs receiving vitamin A at levels over 10 times the requirement [15].
  • In this study, the ultrastructure of the chondrocyte and its pericellular matrix is analyzed in normal growth plates and in growth plates with lesions characteristic of osteochondrosis using aldehyde primary fixatives and osmium-ferrocyanide as the secondary fixative [16].
  • The effect of replacing dietary sodium chloride by sodium bicarbonate on leg weakness, osteochondrosis and growth in young fattening pigs was studied in two experiments using 104 and 126 animals [17].

Other interactions of OSTEO


Analytical, diagnostic and therapeutic context of OSTEO


  1. Porcine osteochondrosis: deficiencies in transforming growth factor-beta and insulin-like growth factor-I. Thorp, B.H., Ekman, S., Jakowlew, S.B., Goddard, C. Calcif. Tissue Int. (1995) [Pubmed]
  2. The ultrastructure of osteochondrosis of the articular-epiphyseal cartilage complex in growing swine. Carlson, C.S., Hilley, H.D., Henrikson, C.K., Meuten, D.J. Calcif. Tissue Int. (1986) [Pubmed]
  3. Experimental ischemia of porcine growth cartilage produces lesions of osteochondrosis. Ytrehus, B., Andreas Haga, H., Mellum, C.N., Mathisen, L., Carlson, C.S., Ekman, S., Teige, J., Reinholt, F.P. J. Orthop. Res. (2004) [Pubmed]
  4. Cartilage canals and lesions typical of osteochondrosis in growth cartilages from the distal part of the humerus of newborn pigs. Visco, D.M., Hill, M.A., Van Sickle, D.C., Kincaid, S.A. Vet. Rec. (1991) [Pubmed]
  5. Economic relevance, diagnosis, and countermeasures for degenerative joint disease (osteoarthrosis) and dyschondroplasia (osteochondrosis) in pigs. Hill, M.A. J. Am. Vet. Med. Assoc. (1990) [Pubmed]
  6. Characterisation of articular and growth plate cartilage collagens in porcine osteochondrosis. Wardale, R.J., Duance, V.C. J. Cell. Sci. (1994) [Pubmed]
  7. Mapping quantitative trait loci for principal components of bone measurements and osteochondrosis scores in a wild boar x large white intercross. Andersson-Eklund, L., Uhlhorn, H., Lundeheim, N., Dalin, G., Andersson, L. Genet. Res. (2000) [Pubmed]
  8. Differences in metabolic parameters and gene expression related to osteochondrosis/osteoarthrosis in pigs fed 25-hydroxyvitamin D3. Jefferies, D., Farquharson, C., Thomson, J., Smith, W., Seawright, E., McCormack, H., Whitehead, C. Vet. Res. (2002) [Pubmed]
  9. Observations on the postnatal morphogenesis of the porcine humeral condyle and the pathogenesis of osteochondrosis. Kincaid, S.A., Lidvall, E.R. Am. J. Vet. Res. (1983) [Pubmed]
  10. Effect of diet on longitudinal bone growth and osteochondrosis in swine. Woodard, J.C., Becker, H.N., Poulos, P.W. Vet. Pathol. (1987) [Pubmed]
  11. Mineral and vitamin nutrition of swine. Miller, E.R., Kornegay, E.T. J. Anim. Sci. (1983) [Pubmed]
  12. Ischemic necrosis of cartilage in spontaneous and experimental lesions of osteochondrosis. Carlson, C.S., Meuten, D.J., Richardson, D.C. J. Orthop. Res. (1991) [Pubmed]
  13. Articular cartilage blood vessels in swine osteochondrosis. Woodard, J.C., Becker, H.N., Poulos, P.W. Vet. Pathol. (1987) [Pubmed]
  14. Trochanter fracture and patellar osteochondrosis as causes of lameness in pigs. Blowey, R.W. Vet. Rec. (1994) [Pubmed]
  15. Tolerance of weanling pigs for dietary vitamin A and D. Blair, R., Burton, B.A., Doige, C.E., Halstead, A.C., Newsome, F.E. International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition. (1989) [Pubmed]
  16. An ultrastructural analysis of osteochondritic growth plate cartilage in growing swine. Farnum, C.E., Wilsman, N.J., Hilley, H.D. Vet. Pathol. (1984) [Pubmed]
  17. The effect of replacement of 0.30% sodium chloride by 0.43% sodium bicarbonate in rations of fattening pigs on leg weakness, osteochondrosis and growth. van der Wal, P.G., Hemminga, H., Goedegebuure, S.A., van der Valk, P.C. The Veterinary quarterly. (1986) [Pubmed]
  18. Age related changes and osteochondrosis in swine articular and epiphyseal cartilage: light ane electron microscopy. Bhatnagar, R., Christian, R.G., Nakano, T., Aherne, F.X., Thompson, J.R. Can. J. Comp. Med. (1981) [Pubmed]
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