Gene Review:
PTBP2 - polypyrimidine tract binding protein 2
Homo sapiens
Synonyms:
NPTB, Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB, PTB, PTB-like protein, ...
- Identification and analysis of the human neural polypyrimidine tract binding protein (nPTB) gene promoter region. Romanelli, M.G., Lorenzi, P., Morandi, C. Gene (2005)
- Molecular cloning and characterization of a new neuron-specific homologue of rat polypyrimidine tract binding protein. Kikuchi, T., Ichikawa, M., Arai, J., Tateiwa, H., Fu, L., Higuchi, K., Yoshimura, N. J. Biochem. (2000)
- Functional significance of the interaction of hepatitis A virus RNA with glyceraldehyde 3-phosphate dehydrogenase (GAPDH): opposing effects of GAPDH and polypyrimidine tract binding protein on internal ribosome entry site function. Yi, M., Schultz, D.E., Lemon, S.M. J. Virol. (2000)
- A novel isoform ratio switch of the polypyrimidine tract binding protein. Wagner, E.J., Carstens, R.P., Garcia-Blanco, M.A. Electrophoresis (1999)
- The polypyrimidine tract-binding protein (PTB) is required for efficient replication of hepatitis C virus (HCV) RNA. Chang, K.S., Luo, G. Virus Res. (2006)
- MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Boutz, P.L., Chawla, G., Stoilov, P., Black, D.L. Genes Dev. (2007)
- Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry. Mitchell, S.A., Spriggs, K.A., Bushell, M., Evans, J.R., Stoneley, M., Le Quesne, J.P., Spriggs, R.V., Willis, A.E. Genes Dev. (2005)
- The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms. Moreira, A., Takagaki, Y., Brackenridge, S., Wollerton, M., Manley, J.L., Proudfoot, N.J. Genes Dev. (1998)
- Characterization of the molecular mechanisms involved in the increased insulin secretion in rats with acute liver failure. Kuwahata, M., Tomoe, Y., Harada, N., Amano, S., Segawa, H., Tatsumi, S., Ito, M., Oka, T., Miyamoto, K. Biochim. Biophys. Acta (2007)
- The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr. Mitchell, S.A., Spriggs, K.A., Coldwell, M.J., Jackson, R.J., Willis, A.E. Mol. Cell (2003)
- The Polypyrimidine Tract Binding Protein (PTB) Represses Splicing of Exon 6B from the {beta}-Tropomyosin Pre-mRNA by Directly Interfering with the Binding of the U2AF65 Subunit. Sauli??re, J., Sureau, A., Expert-Bezan??on, A., Marie, J. Mol. Cell. Biol. (2006)
- Polypyrimidine tract-binding protein down-regulates fibroblast growth factor receptor 1 alpha-exon inclusion. Jin, W., Bruno, I.G., Xie, T.X., Sanger, L.J., Cote, G.J. Cancer Res. (2003)
- Antagonistic regulation of alpha-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein. Gromak, N., Matlin, A.J., Cooper, T.A., Smith, C.W. RNA (2003)
- The Polypyrimidine Tract-binding Protein (PTB) Is Involved in the Post-transcriptional Regulation of Human Inducible Nitric Oxide Synthase Expression. Pautz, A., Linker, K., Hubrich, T., Korhonen, R., Altenh??fer, S., Kleinert, H. J. Biol. Chem. (2006)
- Translation elongation factor-1alpha, La, and PTB interact with the 3' untranslated region of dengue 4 virus RNA. De Nova-Ocampo, M., Villegas-Sepúlveda, N., del Angel, R.M. Virology (2002)
- A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain. Rideau, A.P., Gooding, C., Simpson, P.J., Monie, T.P., Lorenz, M., Hüttelmaier, S., Singer, R.H., Matthews, S., Curry, S., Smith, C.W. Nat. Struct. Mol. Biol. (2006)
- Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane. Stroeken, P.J., Alvarez, B., Van Rheenen, J., Wijnands, Y.M., Geerts, D., Jalink, K., Roos, E. J. Cell. Physiol. (2006)
- Polypyrimidine-tract-binding protein is a component of the HCV RNA replication complex and necessary for RNA synthesis. Aizaki, H., Choi, K.S., Liu, M., Li, Y.J., Lai, M.M. J. Biomed. Sci. (2006)
- Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells. Lassen, K.G., Ramyar, K.X., Bailey, J.R., Zhou, Y., Siliciano, R.F. PLoS Pathog. (2006)