Disease relevance of Myelinolysis, Central Pontine

• Rapid correction of hyponatremia causes demyelination: relation to central pontine myelinolysis [1].
• In this review, we emphasize neuropathologic and neurobehavioral aspects of central pontine and extrapontine myelinolysis (CPM/EPM), also known as the osmotic demyelination syndrome [2].
• Iatrogenic [corrected] extrapontine myelinolysis in central diabetes insipidus: are cyclosporine and 1-desamino-8-D-arginine vasopressin harmful in association [3]?
• Delirium was noted in 16, coma in 9, seizures in 4, and 5 developed focal motor deficits associated with the finding of a brain abscess, transient ischemic attack or central pontine myelinolysis [4].
• Parkinsonism and dystonia in central pontine and extrapontine myelinolysis [5].

Psychiatry related information on Myelinolysis, Central Pontine

• Neurological complications associated with parenteral treatment: central pontine myelinolysis and Wernicke's encephalopathy [6].

High impact information on Myelinolysis, Central Pontine

• A 44-year-old female is described who developed persistent upper extremity and orolingual dystonia several weeks after suspected onset of central pontine myelinolysis (CPM), later confirmed by characteristic pontine lesions on MRI [7].
• Decreased striatal dopamine transporter binding in a patient with extrapontine myelinolysis [8].
• Central pontine myelinolysis as a complication of partial ornithine carbamoyl transferase deficiency [9].
• Central pontine myelinolysis secondary to frequent and rapid shifts in plasma glucose in a diabetic haemodialysis patient [10].
• Diagnosis of incipient central pontine myelinolysis was based on acute brain-stem dysfunction, serum electrolyte disturbances, malnutrition with vitamin B1 (thiamine), B6 (pyridoxine) and B12 (cyanocobalamin) deficiency in combination with typical neuroradiological findings [11].

Chemical compound and disease context of Myelinolysis, Central Pontine

• Isotonic saline is the fluid most commonly used for treatment of asymptomatic hypotonic dehydration, but as shown in the case presented in this article, rapid increase in serum sodium may follow administration of isotonic saline, leading to the development of central pontine myelinolysis (CPM) [12].
• Central pontine myelinolysis associated with acquired folate depletion [13].
• Methylphenidate treatment of neuropsychiatric symptoms of central and extrapontine myelinolysis [14].
• Central pontine myelinolysis: association with parenteral magnesium administration [15].
• The case was diagnosed as CPM and extrapontine myelinolysis (EPM) on the basis of the clinical course and symptoms, and high-dosage steroid therapy was commenced [16].

Gene context of Myelinolysis, Central Pontine

• Acquired focal dystonia following recovery from central pontine myelinolysis [17].
• Treatment of central pontine myelinolysis with thyrotropin-releasing hormone [18].
• The MRI changes of central pontine myelinolysis can also mimic MS [19].
• Extrapontine myelinolysis in a patient with systemic lupus erythematosus: a case report [20].
• The quantitative estimates of the water surfeit or solute deficit, easily performed with simple formulas and measurements, guide accurate and programmed treatment procedures, avoiding the occurrence of the ominous central pontine myelinolysis [21].

Analytical, diagnostic and therapeutic context of Myelinolysis, Central Pontine

• We report two patients with the classical clinical syndrome of central pontine myelinolysis following cisplatin based chemotherapy for nasopharyngeal carcinoma [22].

References