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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Cheirogaleidae


Psychiatry related information on Cheirogaleidae


High impact information on Cheirogaleidae

  • We apply the likelihood models to analyze two mitochondrial protein-coding genes, cytochrome oxidase II and cytochrome b, to estimate divergence times of Malagasy mouse lemurs and related outgroups [4].
  • Binding sites for these proteins also occur near the CCAAT box of other embryonically expressed genes, including rabbit, mouse, and dwarf lemur gamma genes and the human epsilon globin gene [5].
  • Immunohistochemical analysis of cerebral cortical and vascular lesions in the primate Microcebus murinus reveal distinct amyloid beta1-42 and beta1-40 immunoreactivity profiles [6].
  • The nature of the Abeta species in Microcebus murinus brain was investigated immunocytochemically using polyclonal antibodies with clear specificity for the Abeta42 and Abeta40 C-termini [6].
  • We assessed cerebral atrophy in mouse lemur primates (Microcebus murinus) by estimating CSF volume in their brains from 4.7 Tesla T2-weighted magnetic resonance images [7].

Biological context of Cheirogaleidae


Anatomical context of Cheirogaleidae

  • Fos expression following exposure to low levels of irradiance was reduced by 88% in the suprachiasmatic nucleus of aged mouse lemurs [1].
  • Given the functional importance of the cholinergic modulation of endocannabinoid signaling, here we studied CB1 cannabinoid receptor distribution in cholinergic basal forebrain territories and their cortical projection areas in a prosimian primate, the gray mouse lemur [11].

Associations of Cheirogaleidae with chemical compounds


Gene context of Cheirogaleidae


  1. Artificially accelerated aging by shortened photoperiod alters early gene expression (Fos) in the suprachiasmatic nucleus and sulfatoxymelatonin excretion in a small primate, Microcebus murinus. Aujard, F., Dkhissi-Benyahya, O., Fournier, I., Claustrat, B., Schilling, A., Cooper, H.M., Perret, M. Neuroscience (2001) [Pubmed]
  2. Changes in olfactory inputs modify the energy balance response to short days in male gray mouse lemurs. Séguy, M., Perret, M. Physiol. Behav. (2005) [Pubmed]
  3. Daily energy expenditure of the grey mouse lemur (Microcebus murinus): a small primate that uses torpor. Schmid, J., Speakman, J.R. J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. (2000) [Pubmed]
  4. Comparison of likelihood and Bayesian methods for estimating divergence times using multiple gene Loci and calibration points, with application to a radiation of cute-looking mouse lemur species. Yang, Z., Yoder, A.D. Syst. Biol. (2003) [Pubmed]
  5. Differential phylogenetic footprinting as a means to identify base changes responsible for recruitment of the anthropoid gamma gene to a fetal expression pattern. Gumucio, D.L., Shelton, D.A., Blanchard-McQuate, K., Gray, T., Tarle, S., Heilstedt-Williamson, H., Slightom, J.L., Collins, F., Goodman, M. J. Biol. Chem. (1994) [Pubmed]
  6. Immunohistochemical analysis of cerebral cortical and vascular lesions in the primate Microcebus murinus reveal distinct amyloid beta1-42 and beta1-40 immunoreactivity profiles. Mestre-Francés, N., Keller, E., Calenda, A., Barelli, H., Checler, F., Bons, N. Neurobiol. Dis. (2000) [Pubmed]
  7. MRI description of cerebral atrophy in mouse lemur primates. Dhenain, M., Michot, J.L., Privat, N., Picq, J.L., Boller, F., Duyckaerts, C., Volk, A. Neurobiol. Aging (2000) [Pubmed]
  8. Relationship between urinary estrogen levels before conception and sex ratio at birth in a primate, the gray mouse lemur. Perret, M. Hum. Reprod. (2005) [Pubmed]
  9. Taste thresholds and suprathreshold responses to tannin-rich plant extracts and quinine in a primate species (Microcebus murinus). Iaconelli, S., Simmen, B. J. Chem. Ecol. (2002) [Pubmed]
  10. Seasonal variation of taste threshold for sucrose in a prosimian species, Microcebus murinus. Simmen, B., Hladik, C.M. Folia Primatol. (1988) [Pubmed]
  11. Redistribution of CB1 cannabinoid receptors during evolution of cholinergic basal forebrain territories and their cortical projection areas: a comparison between the gray mouse lemur (Microcebus murinus, primates) and rat. Harkany, T., Dobszay, M.B., Cayetanot, F., Härtig, W., Siegemund, T., Aujard, F., Mackie, K. Neuroscience (2005) [Pubmed]
  12. Diurnal variations in plasma testosterone concentrations in the male lesser mouse lemur (Microcebus murinus). Perret, M. J. Reprod. Fertil. (1985) [Pubmed]
  13. Effects of long-term grouping on serum cortisol levels in Microcebus murinus (Prosimii). Perret, M., Predine, J. Hormones and behavior. (1984) [Pubmed]
  14. Aging and season affect plasma dehydroepiandrosterone sulfate (DHEA-S) levels in a primate. Perret, M., Aujard, F. Exp. Gerontol. (2005) [Pubmed]
  15. Social influences on oestrous cycle length and plasma progesterone concentrations in the female lesser mouse lemur (Microcebus murinus). Perret, M. J. Reprod. Fertil. (1986) [Pubmed]
  16. Cloning of the presenilin 2 cDNA and its distribution in brain of the primate, Microcebus murinus: coexpression with betaAPP and Tau proteins. Calenda, A., Mestre-Francés, N., Czech, C., Pradier, L., Petter, A., Perret, M., Bons, N., Bellis, M. Neurobiol. Dis. (1998) [Pubmed]
  17. Quantitative analysis of tau protein-immunoreactive accumulations and beta amyloid protein deposits in the cerebral cortex of the mouse lemur, Microcebus murinus. Giannakopoulos, P., Silhol, S., Jallageas, V., Mallet, J., Bons, N., Bouras, C., Delaère, P. Acta Neuropathol. (1997) [Pubmed]
  18. beta-Amyloid protein precursor in Microcebus murinus: genotyping and brain localization. Silhol, S., Calenda, A., Jallageas, V., Mestre-Frances, N., Bellis, M., Bons, N. Neurobiol. Dis. (1996) [Pubmed]
  19. Molecular cloning, sequencing, and brain expression of the presenilin 1 gene in Microcebus murinus. Calenda, A., Mestre-Francés, N., Czech, C., Pradier, L., Petter, A., Bons, N., Bellis, M. Biochem. Biophys. Res. Commun. (1996) [Pubmed]
  20. Calcium-binding protein distribution in the retina of strepsirhine and haplorhine primates. Chiquet, C., Dkhissi-Benyahya, O., Cooper, H.M. Brain Res. Bull. (2005) [Pubmed]
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