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Disease relevance of Strepsirhini


High impact information on Strepsirhini

  • ZNF91 family members were detected in all species of great apes, gibbons, Old World monkeys, and New World monkeys examined but were not found in prosimians or rodents [2].
  • The involucrin gene of the tarsioids alone contains repeats at both sites, for it derived repeats at site P from a common ancestor of tarsioids and prosimians and a repeat at site M from a later common ancestor of tarsioids and anthropoids [3].
  • It synthesizes an abundance of Gal(alpha 1-3)Gal(beta 1-4)GlcNAc-R (alpha-galactosyl) epitopes within the Golgi apparatus of cells of nonprimate mammals, prosimians, and New World monkeys (platyrrhines) [4].
  • A C-->G substitution in this region converted the mouse sequence CCA GCA to GCA GCA in prosimians, which presumably predisposed this locus to GCA expansion in anthropoids and provides a model for other triplet expansions [5].
  • Taken together, the data indicate that each of the assemblages of DRB genes in prosimians, platyrrhines, and catarrhines is derived from a separate ancestral gene [6].

Biological context of Strepsirhini


Anatomical context of Strepsirhini


Associations of Strepsirhini with chemical compounds

  • New World monkeys are antigenically deficient in all components (measured) except C5, C6, and properdin factor B. Prosimians are antigenically deficient in all components [12].
  • Moreover, tooth-combed prosimians differ from most haplorhines, early Tertiary adapiforms, and arboreal nonprimate eutherians in having a relatively short pisiform body, which gives the flexor carpi ulnaris less power to flex the wrist from extended (= dorsiflexed) positions [13].
  • In this study we used fecal steroid analysis to examine androgen-behavior interactions associated with reproduction in free-ranging male Propithecus verreauxi [14].
  • The effects of age on glutathione synthesis enzymes in lenses of Old World simians and prosimians [15].
  • The concentrations of total calcium, 25-hydroxyvitamin D [25-(OH)D] and 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] were measured in serum obtained from prosimians, the brown lemurs [16].

Gene context of Strepsirhini


Analytical, diagnostic and therapeutic context of Strepsirhini


  1. Testes size and body weight in the Milne-Edwards' sifaka (Propithecus edwardsi) of Ranomafana National Park, Madagascar, relative to other strepsirhine primates. Pochron, S.T., Wright, P.C. Folia Primatol. (2005) [Pubmed]
  2. Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea. Bellefroid, E.J., Marine, J.C., Matera, A.G., Bourguignon, C., Desai, T., Healy, K.C., Bray-Ward, P., Martial, J.A., Ihle, J.N., Ward, D.C. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  3. Involucrin gene of tarsioids and other primates: alternatives in evolution of the segment of repeats. Djian, P., Green, H. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  4. Gene sequences suggest inactivation of alpha-1,3-galactosyltransferase in catarrhines after the divergence of apes from monkeys. Galili, U., Swanson, K. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  5. A trinucleotide repeat-associated increase in the level of Alu RNA-binding protein occurred during the same period as the major Alu amplification that accompanied anthropoid evolution. Chang, D.Y., Sasaki-Tozawa, N., Green, L.K., Maraia, R.J. Mol. Cell. Biol. (1995) [Pubmed]
  6. Alu elements support independent origin of prosimian, platyrrhine, and catarrhine Mhc-DRB genes. Kriener, K., O'hUigin, C., Klein, J. Genome Res. (2000) [Pubmed]
  7. Distribution of human endogenous retrovirus HERV-K genomes in humans and different primates. Steinhuber, S., Brack, M., Hunsmann, G., Schwelberger, H., Dierich, M.P., Vogetseder, W. Hum. Genet. (1995) [Pubmed]
  8. Sex differences in scent marking in Propithecus edwardsi of Ranomafana National Park, Madagascar. Pochron, S.T., Morelli, T.L., Scirbona, J., Wright, P.C. Am. J. Primatol. (2005) [Pubmed]
  9. Humans and old world monkeys have similar patterns of fetal globin expression. Johnson, R.M., Buck, S., Chiu, C.H., Gage, D.A., Shen, T.L., Hendrickx, A.G., Gumucio, D.L., Goodman, M. J. Exp. Zool. (2000) [Pubmed]
  10. Comparative study of human monoclonal anti-D antibodies of IgG and IgM classes in tests with red cells of nonhuman primates. Socha, W.W., Blancher, A., Ruffié, J. Rev. Fr. Transfus. Hemobiol. (1993) [Pubmed]
  11. The morphology of the diencephalon in the Prosimii. II. The Lemuroidea and Lorisoidea. Part I. Thalamus and metathalamus. Simmons, R.M. Journal für Hirnforschung. (1980) [Pubmed]
  12. Phylogeny of complement components in non-human primates. Schur, P.H., Connelly, A., Jones, T.C. J. Immunol. (1975) [Pubmed]
  13. Functional osteology of the primate carpus with special reference to strepsirhini. Hamrick, M.W. Am. J. Phys. Anthropol. (1997) [Pubmed]
  14. Reproduction in free-ranging male Propithecus verreauxi: the hormonal correlates of mating and aggression. Brockman, D.K., Whitten, P.L., Richard, A.F., Schneider, A. Am. J. Phys. Anthropol. (1998) [Pubmed]
  15. The effects of age on glutathione synthesis enzymes in lenses of Old World simians and prosimians. Rathbun, W.B., Holleschau, A.M. Curr. Eye Res. (1992) [Pubmed]
  16. Serum concentrations of calcium and vitamin D metabolites in prosimians. Gray, T.K., Lester, G.E., Moore, G., Crews, D., Simons, E.L., Stuart, M. J. Med. Primatol. (1982) [Pubmed]
  17. The involucrin genes of pig and dog: comparison of their segments of repeats with those of prosimians and higher primates. Tseng, H., Green, H. Mol. Biol. Evol. (1990) [Pubmed]
  18. Evolution of RPS4Y. Bergen, A.W., Pratt, M., Mehlman, P.T., Goldman, D. Mol. Biol. Evol. (1998) [Pubmed]
  19. Episodic evolution of growth hormone in primates and emergence of the species specificity of human growth hormone receptor. Liu, J.C., Makova, K.D., Adkins, R.M., Gibson, S., Li, W.H. Mol. Biol. Evol. (2001) [Pubmed]
  20. Molecular evolutionary dynamics of cytochrome b in strepsirrhine primates: the phylogenetic significance of third-position transversions. Yoder, A.D., Vilgalys, R., Ruvolo, M. Mol. Biol. Evol. (1996) [Pubmed]
  21. The effects of age on glutathione peroxidase and glutathione reductase activities in lenses of Old World simians and prosimians. Holleschau, A.M., Rathbun, W.B. Curr. Eye Res. (1994) [Pubmed]
  22. Increase in tannin consumption by sifaka ( Propithecus verreauxi verreauxi) females during the birth season: a case for self-medication in prosimians? Carrai, V., Borgognini-Tarli, S.M., Huffman, M.A., Bardi, M. Primates (2003) [Pubmed]
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