Disease relevance of Strepsirhini

• Testes size and body weight in the Milne-Edwards' sifaka (Propithecus edwardsi) of Ranomafana National Park, Madagascar, relative to other strepsirhine primates [1].

High impact information on Strepsirhini

• ZNF91 family members were detected in all species of great apes, gibbons, Old World monkeys, and New World monkeys examined but were not found in prosimians or rodents [2].
• The involucrin gene of the tarsioids alone contains repeats at both sites, for it derived repeats at site P from a common ancestor of tarsioids and prosimians and a repeat at site M from a later common ancestor of tarsioids and anthropoids [3].
• It synthesizes an abundance of Gal(alpha 1-3)Gal(beta 1-4)GlcNAc-R (alpha-galactosyl) epitopes within the Golgi apparatus of cells of nonprimate mammals, prosimians, and New World monkeys (platyrrhines) [4].
• A C-->G substitution in this region converted the mouse sequence CCA GCA to GCA GCA in prosimians, which presumably predisposed this locus to GCA expansion in anthropoids and provides a model for other triplet expansions [5].
• Taken together, the data indicate that each of the assemblages of DRB genes in prosimians, platyrrhines, and catarrhines is derived from a separate ancestral gene [6].

Biological context of Strepsirhini

• We detected HERV-K genomes in Macaca mulatta and Macaca silenus, which represent Old World monkeys, but not in prosimians (Galago demidovii) and New World monkeys, represented by Saguinus fuscicollis, Saguinus oedipus, and Callithrix iacchus [7].
• Sex differences in scent marking in Propithecus edwardsi of Ranomafana National Park, Madagascar [8].
• Thus, the catarrhines seem to share a common pattern of developmental switching in the beta-globin gene cluster, which is distinct from the timing of expression in either prosimians or the New World monkeys [9].

Anatomical context of Strepsirhini

• Forty-nine human anti-D (Rho) monoclonal antibodies of the IgG and IgM classes were tested with red blood cells of various nonhuman primates, from anthropoid apes to Prosimians, and significant differences in reactivity were observed among antibodies of two classes depending on taxonomic position of primate animals [10].
• The morphology of the diencephalon in the Prosimii. II. The Lemuroidea and Lorisoidea. Part I. Thalamus and metathalamus [11].

Associations of Strepsirhini with chemical compounds

• New World monkeys are antigenically deficient in all components (measured) except C5, C6, and properdin factor B. Prosimians are antigenically deficient in all components [12].
• Moreover, tooth-combed prosimians differ from most haplorhines, early Tertiary adapiforms, and arboreal nonprimate eutherians in having a relatively short pisiform body, which gives the flexor carpi ulnaris less power to flex the wrist from extended (= dorsiflexed) positions [13].
• In this study we used fecal steroid analysis to examine androgen-behavior interactions associated with reproduction in free-ranging male Propithecus verreauxi [14].
• The effects of age on glutathione synthesis enzymes in lenses of Old World simians and prosimians [15].
• The concentrations of total calcium, 25-hydroxyvitamin D [25-(OH)D] and 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] were measured in serum obtained from prosimians, the brown lemurs [16].

Gene context of Strepsirhini

• The involucrin genes of pig and dog: comparison of their segments of repeats with those of prosimians and higher primates [17].
• These data support a transposition event of ancestral primate RPS4X to the Y chromosome prior to the divergence of Prosimii [18].
• To address the above issues, we sequenced GH and GHR genes in prosimians and simians [19].
• A study (Adkins and Honeycutt 1994) of the cytochrome c oxidase subunit II (COII) gene placed one Malagasy primate (Daubentonia) at the base of the strepsirrhine clade, thereby suggesting a diphyletic Lemuriformes [20].
• The effects of age on glutathione peroxidase and glutathione reductase activities in lenses of Old World simians and prosimians [21].

Analytical, diagnostic and therapeutic context of Strepsirhini

• Increase in tannin consumption by sifaka ( Propithecus verreauxi verreauxi) females during the birth season: a case for self-medication in prosimians [22]?

References