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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Furcation Defects

 
 
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Disease relevance of Furcation Defects

  • The purpose of this present study was to confirm resolution of ankylosis during periodontal regeneration by recombinant human BMP-2 (rhBMP-2) applied to class III furcation defects [1].
 

High impact information on Furcation Defects

 

Chemical compound and disease context of Furcation Defects

 

Biological context of Furcation Defects

 

Anatomical context of Furcation Defects

 

Gene context of Furcation Defects

  • The purpose of this study was to evaluate the effectiveness of PRP, BPBM and GTR used in combination as regenerative treatment for grade II molar furcation defects in humans [4].
  • Regeneration of Class III furcation defects with basic fibroblast growth factor (b-FGF) associated with GTR. A descriptive and histometric study in dogs [15].
  • Repair of periodontal furcation defects in beagle dogs following reconstructive surgery including root surface demineralization with tetracycline hydrochloride and topical fibronectin application [16].
  • RESULTS: Surgical treatment revealed significant PPD reduction (- 3.45 +/- 1.56 mm; P < 0.001), PAL-V gain (2.84 +/- 1.36 mm; P < 0.001), and PBL-V gain (1.68 +/- 1.20 mm; P < 0.001) in infrabony defects, as well as PPD reduction (- 1.68 +/- 1.73 mm; P = 0.001) and PAL-H gain [1.43 +/- 1.70 mm (P = 0.001)] in furcation defects after 5 years [17].
  • Modified coronally positioned flap for obtaining new attachment in Class 2 and 3 furcation defects. Part I: Rationale and surgical technique [18].
 

Analytical, diagnostic and therapeutic context of Furcation Defects

References

  1. Formation and resolution of ankylosis under application of recombinant human bone morphogenetic protein-2 (rhBMP-2) to class III furcation defects in cats. Takahashi, D., Odajima, T., Morita, M., Kawanami, M., Kato, H. J. Periodont. Res. (2005) [Pubmed]
  2. Periodontal tissue regeneration in beagle dogs after laser therapy. Crespi, R., Covani, U., Margarone, J.E., Andreana, S. Lasers in surgery and medicine. (1997) [Pubmed]
  3. Recombinant human basic fibroblast growth factor (bFGF) stimulates periodontal regeneration in class II furcation defects created in beagle dogs. Murakami, S., Takayama, S., Kitamura, M., Shimabukuro, Y., Yanagi, K., Ikezawa, K., Saho, T., Nozaki, T., Okada, H. J. Periodont. Res. (2003) [Pubmed]
  4. Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans. Lekovic, V., Camargo, P.M., Weinlaender, M., Vasilic, N., Aleksic, Z., Kenney, E.B. Journal of clinical periodontology. (2003) [Pubmed]
  5. Wound healing of degree III furcation involvements following guided tissue regeneration and/or Emdogain. A histologic study. Donos, N., Sculean, A., Glavind, L., Reich, E., Karring, T. Journal of clinical periodontology. (2003) [Pubmed]
  6. Comparison of three methods using calcium sulfate as a graft/barrier material for the treatment of Class II mandibular molar furcation defects. Maragos, P., Bissada, N.F., Wang, R., Cole, B.P. The International journal of periodontics & restorative dentistry. (2002) [Pubmed]
  7. Recurrence of mandibular molar furcation defects following citric acid root treatment and coronally advanced flap procedures. Haney, J.M., Leknes, K.N., Wikesjö, U.M. The International journal of periodontics & restorative dentistry. (1997) [Pubmed]
  8. The use of biodegradable polylactic acid barrier materials in the treatment of grade II periodontal furcation defects in humans--Part II: A multicenter investigative surgical study. Vernino, A.R., Wang, H.L., Rapley, J., Nechamkin, S.J., Ringeisen, T.A., Derhalli, M., Brekke, J. The International journal of periodontics & restorative dentistry. (1999) [Pubmed]
  9. Treatment of class II furcation defects using porous hydroxylapatite in conjunction with a polytetrafluoroethylene membrane. Lekovic, V., Kenney, E.B., Carranza, F.A., Danilovic, V. J. Periodontol. (1990) [Pubmed]
  10. Clinical evaluation of the effect of tetracycline root preparation on guided tissue regeneration in the treatment of Class II furcation defects. Parashis, A.O., Mitsis, F.J. J. Periodontol. (1993) [Pubmed]
  11. GTR treatment of degree III furcation defects following application of enamel matrix proteins. An experimental study in dogs. Araújo, M.G., Lindhe, J. Journal of clinical periodontology. (1998) [Pubmed]
  12. Guided periodontal tissue regeneration in Class II furcation defects following treatment with a synthetic bioabsorbable barrier. Hürzeler, M.B., Quiñones, C.R., Caffesse, R.G., Schüpbach, P., Morrison, E.C. J. Periodontol. (1997) [Pubmed]
  13. Regenerative therapy of furcation defect. Dryankova, M.M., Popova, C.L. Folia medica. (2001) [Pubmed]
  14. Evaluation of periodontal healing in class II furcation defects following guided tissue regeneration with two different types of polylactic acid membranes. Cetiner, D., Unsal, B., Parlar, A., Gültekin, E., Kurtiş, B. Chin. Med. J. (2004) [Pubmed]
  15. Regeneration of Class III furcation defects with basic fibroblast growth factor (b-FGF) associated with GTR. A descriptive and histometric study in dogs. Rossa, C., Marcantonio, E., Cirelli, J.A., Marcantonio, R.A., Spolidorio, L.C., Fogo, J.C. J. Periodontol. (2000) [Pubmed]
  16. Repair of periodontal furcation defects in beagle dogs following reconstructive surgery including root surface demineralization with tetracycline hydrochloride and topical fibronectin application. Wikesjö, U.M., Claffey, N., Christersson, L.A., Franzetti, L.C., Genco, R.J., Terranova, V.P., Egelberg, J. Journal of clinical periodontology. (1988) [Pubmed]
  17. Evidence for healing of periodontal defects 5 years after conventional and regenerative therapy: digital subtraction and bone level measurements. Eickholz, P., Hausmann, E. Journal of clinical periodontology. (2002) [Pubmed]
  18. Modified coronally positioned flap for obtaining new attachment in Class 2 and 3 furcation defects. Part I: Rationale and surgical technique. Froum, S.J., Tarnow, D. The International journal of periodontics & restorative dentistry. (1995) [Pubmed]
  19. Treatment of mandibular class III periodontal furcation defects. Coronally positioned flaps with and without expanded polytetrafluoroethylene membranes. Garrett, S., Gantes, B., Zimmerman, G., Egelberg, J. J. Periodontol. (1994) [Pubmed]
  20. Comparison of a bioabsorbable GTR barrier to a non-absorbable barrier in treating human class II furcation defects. A multi-center parallel design randomized single-blind trial. Garrett, S., Polson, A.M., Stoller, N.H., Drisko, C.L., Caton, J.G., Harrold, C.Q., Bogle, G., Greenwell, H., Lowenguth, R.A., Duke, S.P., DeRouen, T.A. J. Periodontol. (1997) [Pubmed]
 
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